articles
- A Toxic RNA Templates the Synthesis of Its Own Fluorogenic Inhibitor by Using a Bio-orthogonal Tetrazine Ligation in Cells and Tissues. 15:1820-1825. 2020
- Hydrocarbon-Stitched Peptide Agonists of Glucagon-Like Peptide-1 Receptor. 15:1340-1348. 2020
- 3-Oxo-β-sultam as a Sulfonylating Chemotype for Inhibition of Serine Hydrolases and Activity-Based Protein Profiling. 15:878-883. 2020
- Blockade of the Lysophosphatidylserine Lipase ABHD12 Potentiates Ferroptosis in Cancer Cells. 15:871-877. 2020
- Cell-Based Ligand Discovery for the ENL YEATS Domain. 15:895-903. 2020
- Precise Targeted Cleavage of a r(CUG) Repeat Expansion in Cells by Using a Small-Molecule-Deglycobleomycin Conjugate. 15:849-855. 2020
- hFUT1-Based Live-Cell Assay To Profile α1-2-Fucoside-Enhanced Influenza Virus A Infection. 15:819-823. 2020
- The impact of sustained immunization regimens on the antibody response to oligomannose glycans. 15:789-798. 2020
- Integrative X-ray structure and molecular modeling for the rationalization of procaspase-8 inhibitor potency and selectivity. 15:575-586. 2020
- Structure-specific cleavage of an RNA repeat expansion with a dimeric small molecule is advantageous over sequence-specific recognition by an oligonucleotide. 15:485-493. 2020
- An Irreversible Inhibitor to Probe the Role of Streptococcus pyogenes Cysteine Protease SpeB in Evasion of Host Complement Defenses. 15:2060-2069. 2020
- Gini Coefficients as a Single Value Metric to Define Chemical Probe Selectivity. 15:2031-2040. 2020
- Mapping RNAPII CTD phosphorylation reveals that the identity and modification of seventh heptad residues direct Tyr1 phosphorylation. 14:2264-2275. 2019
- A single reactive noncanonical amino acid is able to dramatically stabilize protein structure. 14:1150-1153. 2019
- Discovery of kirromycins with anti-Wolbachia activity from Streptomyces sp. CB00686. 14:1174-1182. 2019
- PF-06651600, a dual JAK3/TEC family kinase inhibitor. 14:1235-1242. 2019
- A nonaggregating heptamethine cyanine for building brighter labeled biomolecules. 14:934-940. 2019
- Unique polypharmacology nuclear receptor modulator blocks inflammatory signaling pathways. 14:1051-1062. 2019
- Deconvoluting stress-responsive proteostasis signaling pathways for pharmacologic activation using targeted RNA sequencing. 14:784-795. 2019
- Exploiting CD22 to selectively tolerize autoantibody producing B-cells in rheumatoid arthritis. 14:644-654. 2019
- Global portrait of protein targets of metabolites of the neurotoxic compound BIA 10-2474. 14:192-197. 2019
- Responsible peer review. 13:3217-3218. 2018
- Precise small molecule degradation of a noncoding RNA identifies cellular binding sites and modulates an oncogenic phenotype. 13:3065-3071. 2018
- A chemical biology approach to model pontocerebellar hypoplasia type 1B (PCH1B). 13:3000-3010. 2018
- A commensal dipeptidyl aminopeptidase with specificity for N-terminal glycine degrades human-produced antimicrobial peptides in vitro. 13:2513-2521. 2018
- Biochemical and structural characterization of TtnD, a prenylated FMN-dependent decarboxylase from the tautomycetin biosynthetic pathway. 13:2728-2738. 2018
- Probing the flexibility of an iterative modular polyketide synthase with non-native substrates in vitro. 13:2261-2268. 2018
- Antitumor humoral and T cell responses by mucin-1 conjugates of bacteriophage Qβ in wild-type mice. 13:1668-1676. 2018
- Chemical probe to identify the cellular targets of the reactive lipid metabolite 2-trans-hexadecenal. 13:1130-1136. 2018
- Mechanism of action of the cytotoxic asmarine alkaloids. 13:1299-1306. 2018
- Playing with the molecules of life. 13:854-870. 2018
- Structural and functional studies of a pyran synthase domain from a trans-acyltransferase assembly line. 13:975-983. 2018
- Site-specific incorporation of a thioester containing amino acid into proteins. 13:578-581. 2018
- Rheostatic control of Cas9-mediated DNA double strand break (DSB) generation and genome editing. 13:438-442. 2018
- ToP-DNJ, a selective inhibitor of endoplasmic reticulum α-glucosidase II Exhibiting Antiflaviviral Activity. 13:60-65. 2018
- Large scale mutational and kinetic analysis of a self-hydrolyzing deoxyribozyme. 12:2940-2945. 2017
- Profiling of protein O-GIcNAcylation in murine CD8(+) effector- and memory-like T cells. 12:3031-3038. 2017
- Discovery of a distinct chemical and mechanistic class of allosteric HIV-1 integrase inhibitors with antiretroviral activity. 12:2858-2865. 2017
- Targeted disruption of Myc-Max oncoprotein complex by a small molecule. 12:2715-2719. 2017
- Mapping Protein Targets of Bioactive Small Molecules Using Lipid-Based Chemical Proteomics. 12:2671-2681. 2017
- Linking high-throughput screens to identify MoAs and novel inhibitors of Mycobacterium tuberculosis dihydrofolate reductase. 12:2448-2456. 2017
- Ventromorphins: a new class of small molecule activators of the canonical BMP signaling pathway. 12:2436-2447. 2017
- Quantitative chemical proteomic profiling of the in vivo targets of reactive drug metabolites. 12:2040-2050. 2017
- P450-mediated non-natural cyclopropanation of dehydroalanine-containing thiopeptides. 12:1726-1731. 2017
- Substrate profiling and high resolution co-complex crystal structure of a secreted C11 protease conserved across commensal bacteria. 12:1556-1565. 2017
- Halogen-π interactions in the cytochrome P450 active site: Structural insights into human CYP2B6 substrate selectivity. 12:1204-1210. 2017
- Chemoproteomic screening of covalent ligands reveals UBA5 as a novel pancreatic cancer target. 12:899-904. 2017
- Modification of the orthosteric PPARγ covalent antagonist scaffold yields an improved dual-site allosteric inhibitor. 12:969-978. 2017
- Exploring the structural compliancy versus specificity of the estrogen receptor uUsing isomeric three-dimensional ligands. 12:494-503. 2017
- Global N-glycan site occupancy of HIV-1 gp120 by metabolic engineering and high-resolution intact mass spectrometry. 12:357-361. 2017
- Development of 5N-bicalutamide, a high-affinity reversible covalent antiandrogen. 12:2934-2939. 2017
- Tools for studying glycans: Recent advances in chemoenzymatic glycan labeling. 12:611-621. 2017
- An Advance in Prescription Opioid Vaccines: Overdose Mortality Reduction and Extraordinary Alteration of Drug Half-Life. 12:36-40. 2017
- An effective bacterial fucosidase for glycoprotein remodeling. 12:63-72. 2017
- High-throughput identification of DNA-encoded IgG ligands that distinguish active and latent Mycobacterium tuberculosis infections. 12:234-243. 2017
- Mapping the phosphorylation pattern of Drosophila melanogaster RNA polymerase II carboxyl-terminal domain using ultraviolet photodissociation mass spectrometry. 12:153-162. 2017
- Observing biosynthetic activity utilizing next generation sequencing and the DNA linked enzyme coupled assay. 12:191-199. 2017
- Discovery of a JAK3-selective inhibitor: functional differentiation of JAK3-selective inhibition over pan-JAK or JAK1-selective inhibition. 11:3442-3451. 2016
- Phenyl glycolipids with different glycosyl groups exhibit marked differences in murine and human iNKT cell activation. 11:3431-3441. 2016
- Challenges in targeting a basic helix-loop-helix transcription factor with hydrocarbon-stapled peptides. 11:3146-3153. 2016
- Rational design of dual agonist-antibody fusions as long-acting therapeutic hormones. 11:2991-2995. 2016
- Small molecule inhibitor of NRF2 selectively intervenes therapeutic resistance in KEAP1-deficient NSCLC tumors. 11:3214-3225. 2016
- Selectivity in small molecule splicing modulation. 11:2716-2723. 2016
- Discovery of a selective covalent inhibitor of lysophospholipase-like 1 (LYPLAL1) as a tool to evaluate the role of this serine hydrolase in metabolism. 11:2529-2540. 2016
- Small molecule recognition and tools to study modulation of r(CGG)(exp) in fragile X-associated tremor ataxia syndrome. 11:2456-2465. 2016
- Albumin-oxanorbornadiene conjugates formed ex vivo for the extended circulation of hydrophilic cargo. 11:2320-2327. 2016
- Development of chemical probes for investigation of salt-inducible kinase function in vivo. 11:2105-2111. 2016
- Identification of a binding site for unsaturated fatty acids in the orphan nuclear receptor Nurr1. 11:1795-1799. 2016
- Inhibition of zinc-dependent histone deacetylases with a chemically triggered electrophile. 11:1844-1851. 2016
- Stabilizing the C(H)2 domain of an antibody by engineering in an enhanced aromatic sequon. 11:1852-1861. 2016
- Global isotope metabolomics reveals adaptive strategies for nitrogen assimilation. 11:1677-1685. 2016
- Inforna 2.0: a platform for the sequence-based design of small molecules targeting structured RNAs. 11:1720-1728. 2016
- Site-specific radiofluorination of biomolecules with 8-[(18)F]-fluorooctanoic acid catalyzed by lipoic acid ligase. 11:1587-1594. 2016
- FRET characterization of complex conformational changes in a large 165 ribosomal RNA fragment site-specifically labeled using unnatural base pairs. 11:1347-1353. 2016
- The Competitive Interplay between Allosteric HIV-1 Integrase Inhibitor BI/D and LEDGF/p75 during the Early Stage of HIV-1 Replication Adversely Affects Inhibitor Potency. 11:1313-1321. 2016
- Cutting edge chemical biology: Report from the 2016 International Symposium on Chemical Biology, January 13-15, Geneva, Switzerland. 11:816-820. 2016
- Synthetic RORγt agonists enhance protective immunity. 11:1012-1018. 2016
- Design of potent and proteolytically stable oxyntomodulin analogs. 11:324-328. 2016
- Small molecule targeting of a microRNA associated with hepatocellular carcinoma. 11:375-380. 2016
- First-in-class inhibitors of sulfur metabolism with bactericidal activity against non-replicating M. tuberculosis. 11:172-184. 2016
- SR2067 reveals a unique kinetic and structural signature for PPARγ partial agonism. 11:273-283. 2016
- Selective targeting of extracellular insulin-degrading enzyme by quasi-irreversible thiol-modifying inhibitors. 10:2716-2724. 2015
- Studying a drug-like, RNA-focused small molecule library identifies compounds that inhibit RNA toxicity in myotonic dystrophy. 10:2706-2715. 2015
- Chemical proteomic platform to identify citrullinated proteins. 10:2520-2528. 2015
- Mechanism-based post-translational modification and inactivation in terpene synthases. 10:2501-2511. 2015
- A small molecule inhibits deregulated NRF2 transcriptional activity in cancer. 10:2193-2198. 2015
- Chemical tools to decipher regulation of phosphatases by proline isomerization on eukaryotic RNA polymerase II. 10:2405-2414. 2015
- Small molecule inhibition of miR-544 biogenesis disrupts adaptive responses to hypoxia by modulating ATM-mTOR signaling. 10:2267-2276. 2015
- A chemical approach for the detection of protein sulfinylation. 10:1825-1830. 2015
- Ribosomal synthesis of macrocyclic peptides in vitro and in vivo mediated by genetically encoded aminothiol unnatural amino acids. 10:1805-1816. 2015
- Withaferin A analogs that target the AAA plus chaperone p97. 10:1916-1924. 2015
- Activity-based protein profiling of oncogene-driven changes in metabolism reveals broad dysregulation of PAFAH1B2 and 1B3 in cancer. 10:1624-1630. 2015
- Genetic incorporation of ε-N-2-hydroxyisobutyryl-lysine into recombinant histones. 10:1599-1603. 2015
- A nonapoptotic role for BAX and BAK in eicosanoid metabolism. 10:1398-1403. 2015
- Constructing de novo H2O2 signaling via induced protein proximity. 10:1404-1410. 2015
- Protein arginine deiminase 2 binds calcium in an ordered fashion: implications for inhibitor design. 10:1043-1053. 2015
- Selective inhibitor of platelet-activating factor acetylhydrolases 1b2 and 1b3 that impairs cancer cell survival. 10:925-932. 2015
- Discovery of native autoantigens via antigen surrogate technology: Application to type 1 diabetes. 10:401-412. 2015
- Target-based screen against a periplasmic serine protease that regulates intrabacterial pH homeostasis in Mycobacterium tuberculosis. 10:364-371. 2015
- Clickable analogue of cerulenin as chemical probe to explore protein palmitoylation. 10:115-121. 2015
- Chemoproteomics demonstrates target engagement and exquisite selectivity of the clinical phosphodiesterase 10A inhibitor MP-10 in its native environment. 9:2823-2832. 2014
- Development and structural analysis of a nanomolar cyclic peptide antagonist for the EphA4 receptor. 9:2787-2795. 2014
- Exploring a 2-naphthoic acid template for the structure-based design of P2Y14 receptor antagonist molecular probes. 9:2833-2842. 2014
- Discovery of a highly selective caspase-3 substrate for imaging live cells. 9:2199-2203. 2014
- Selective inhibition of initiator versus executioner caspases using small peptides containing unnatural amino acids. 9:2194-2198. 2014
- Heat-shock response transcriptional program enables high-yield and high-quality recombinant protein production in Escherichia coli. 9:1945-1949. 2014
- Structure, biochemistry, and inhibition of essential 4'-phosphopantetheinyl transferases from two species of Mycobacteria. 9:1939-1944. 2014
- Carlos F. Barbas III (1964-2014): Visionary at the interface of chemistry and biology. 9:1645-1646. 2014
- Divergent modulation of Src-family kinase regulatory interactions with ATP-competitive inhibitors. 9:1894-1905. 2014
- Protein delivery using Cys2-His2 zinc-finger domains. 9:1662-1667. 2014
- Characterizing the altered cellular proteome induced by the stress-independent activation of heat shock factor 1. 9:1273-1283. 2014
- Genetic incorporation of histidine derivatives using an engineered pyrrolysyl-tRNA synthetase. 9:1092-1096. 2014
- A FluoPol-ABPP PAD2 high-throughput screen identifies the first calcium site inhibitor targeting the PADs. 9:913-921. 2014
- Role of tRNA orthogonality in an expanded genetic code. 9:874-879. 2014
- Targeting the r(CGG) repeats that cause FXTAS with modularly assembled small molecules and oligonucleotides. 9:904-912. 2014
- Using unnatural amino acid mutagenesis to probe the regulation of PRMT1. 9:649-655. 2014
- A liquid array platform for the multiplexed analysis of synthetic molecule-protein interactions. 9:339-346. 2014
- Discovery of light-responsive ligands through screening of a light-responsive genetically encoded library. 9:443-450. 2014
- Inhibiting AMPylation: a novel screen to identify the first small molecule inhibitors of protein AMPylation. 9:433-442. 2014
- Structure of the myotonic dystrophy type 2 RNA and designed small molecules that reduce toxicity. 9:538-550. 2014
- Small molecules for cell reprogramming and heart repair: progress and perspective. 9:34-44. 2014
- Engineering the polyproline II propensity of a class II major histocompatibility complex ligand peptide. 8:2383-2387. 2013
- Exploring binding and effector functions of natural human antibodies using synthetic immunomodulators. 8:2404-2411. 2013
- An antibody CDR3-erythropoietin fusion protein. 8:2117-2121. 2013
- Features of modularly assembled compounds that impart bioactivity against an RNA target. 8:2312-2321. 2013
- Novel modifications on C-terminal domain of RNA polymerase II can fine-tune the phosphatase activity of Ssu72. 8:2042-2052. 2013
- Targeting the arginine phosphatase YwlE with a catalytic redox-based inhibitor. 8:2024-2032. 2013
- A small molecule bidentate-binding dual inhibitor probe of the LRRK2 and JNK kinases. 8:1747-1754. 2013
- A small molecule bidentate-binding dual inhibitor probe of the LRRK2 and JNK kinases. 8:1747-1754. 2013
- An expanded genetic code in mammalian cells with a functional quadruplet codon. 8:1640-1645. 2013
- Discovery of a selective irreversible BMX inhibitor for prostate cancer. 8:1423-1428. 2013
- On-chip synthesis and screening of a sialoside library yields a high affinity ligand for Siglec-7. 8:1417-1422. 2013
- Proteome-wide reactivity profiling identifies diverse carbamate chemotypes tuned for serine hydrolase inhibition. 8:1590-1599. 2013
- Selective Detection of Caspase-3 versus Caspase-7 Using Activity-Based Probes with Key Unnatural Amino Acids. 8:1558-1566. 2013
- Small molecule mediated proliferation of primary retinal pigment epithelial cells. 8:1407-1411. 2013
- Boosting immunity to small tumor-associated carbohydrates with bacteriophage Qβ capsids. 8:1253-1262. 2013
- Design, synthesis, and kinetic characterization of protein N-terminal acetyltransferase inhibitors. 8:1121-1127. 2013
- Facilitating cytokine-mediated cancer cell death by proteobacterial N-acylhomoserine lactones. 1117-1120. 2013
- Persulfide reactivity in the detection of protein S-sulfhydration. 8:1110-1116. 2013
- Small molecule regulation of protein conformation by binding in the flap of HIV protease. 1223-1231. 2013
- Synthesis and SAR of lehualide B: A marine-derived natural product with potent anti-multiple myeloma activity. 8:1241-1252. 2013
- Eupalinilide E inhibits erythropoiesis and promotes the expansion of hematopoietic progenitor cells. 8:866-870. 2013
- Potent and selective inhibition of A-to-I RNA editing with 2'-O-methyl/locked nucleic acid-containing antisense oligoribonucleotides. 8:832-839. 2013
- A liver-selective LXR inverse agonist that suppresses hepatic steatosis. 8:559-567. 2013
- Mechanism and in vitro pharmacology of TAK1 inhibition by (5Z)-7-Oxozeaenol. 8:643-650. 2013
- Regulating the ARNT/TACC3 axis: multiple approaches to manipulating protein/protein interactions with small molecules. 8:626-635. 2013
- Chemoproteomic profiling identifies changes in DNA-PK as markers of early dengue virus infection. 7:2019-2026. 2012
- Novel selective allosteric and bitopic ligands for the S1P(3) receptor. 7:1975-1983. 2012
- Rational design of bioactive, modularly assembled aminoglycosides targeting the RNA that causes myotonic dystrophy type 1. 7:1984-1993. 2012
- Manipulating JNK signaling with (-)-zuonin A. 7:1873-1883. 2012
- Probing a 2-aminobenzimidazole library for binding to RNA internal loops via two-dimensional combinatorial screening. 7:1902-1909. 2012
- Uncoupling intramolecular processing and substrate hydrolysis in the N-terminal nucleophile hydrolase hASRGL1 by circular permutation. 7:1840-1847. 2012
- A small molecule that targets r(CGG)(exp) and improves defects in fragile X-associated tremor ataxia syndrome. 7:1711-1718. 2012
- Selective penicillin-binding protein imaging probes reveal substructure in bacterial cell division. 7:1746-1753. 2012
- Identification of a selective ROR gamma ligand that suppresses T(H)17 cells and stimulates T regulatory cells. 7:1515-1519. 2012
- Release factor one is nonessential in Escherichia coli. 7:1337-1344. 2012
- Structural and kinetic analysis of prolyl-isomerization/phosphorylation cross-talk in the CTD code. 7:1462-1470. 2012
- Agonists for 13 trace amine-associated receptors provide insight into the molecular basis of odor selectivity. 7:1184-1189. 2012
- Novel inhibitors for PRMT1 discovered by high-throughput screening using activity-based fluorescence polarization. 7:1198-1204. 2012
- Mutasynthesis of a potent anticancer sibiromycin analogue. 7:973-977. 2012
- Selective ATP-competitive inhibitors of TOR suppress rapamycin-insensitive function of TORC2 in Saccharomyces cerevisiae. 7:982-987. 2012
- Selective identification of hedgehog pathway antagonists by direct analysis of smoothened ciliary translocation. 7:1040-1048. 2012
- Tyrosine cross-linking reveals interfacial dynamics in adeno-associated viral capsids during infection. 7:1059-1066. 2012
- Glycan fingerprints: Calculating diversity in glycan libraries. 7:829-834. 2012
- Rationally designed small molecules targeting the RNA that causes myotonic dystrophy type 1 are potently bioactive. 7:856-862. 2012
- Redesign of glycopeptide antibiotics: back to the future. 7:797-804. 2012
- Small-molecule inhibitors of bacterial AddAB and RecBCD helicase-nuclease DNA repair enzymes. 7:879-891. 2012
- Identification of SR2211: a potent synthetic ROR gamma-selective modulator. 7:672-677. 2012
- 2'-Azido RNA, a versatile tool for chemical biology: synthesis, X-ray structure, siRNA applications, click labeling. 7:581-589. 2012
- Chemical correction of pre-mRNA splicing defects associated with sequestration of muscleblind-like 1 protein by expanded r(CAG)-containing transcripts. 7:496-505. 2012
- Engineering transaldolase in Pichia stipitis to improve bioethanol production. 7:481-486. 2012
- First-in-class small molecule inhibitors of the single-strand DNA cytosine deaminase APOBEC3G. 7:506-517. 2012
- Three ring posttranslational circuses: insertion of oxazoles, thiazoles, and pyridines into protein-derived frameworks. 7:429-442. 2012
- Iron-sulfur cluster engineering provides insight into the evolution of substrate specificity among sulfonucleotide reductases. 7:305-314. 2012
- Recent advances in developing small molecules targeting RNA. 7:73-86. 2012
- Synthesis and screening of a haloacetamidine containing library to identify PAD4 selective inhibitors. 7:160-165. 2012
- Cellobiose dehydrogenase and a copper-dependent polysaccharide monooxygenase potentiate cellulose degradation by neurospora crassa. 6:1399-1406. 2011
- A chemical genomic analysis of decoquinate, a plasmodium falciparum cytochrome b inhibitor. 6:1214-1222. 2011
- A chemically induced vaccine strategy for prostate cancer. 6:1223-1231. 2011
- N-PEGylation of a reverse turn is stabilizing in multiple sequence contexts, unlike N-GlcNAcylation. 6:1188-1192. 2011
- Activity-based protein profiling of protein arginine methyltransferase 1. 6:1127-1135. 2011
- Similarities and differences between two modes of antagonism of the thyroid hormone receptor. 6:1096-1106. 2011
- Kinase consensus sequences: A breeding ground for crosstalk. 6:881-892. 2011
- Selective inhibition of mitochondrial jnk signaling achieved using peptide mimicry of the sab kinase interacting motif-1 (kim1). 6:808-818. 2011
- Identification of a novel non-retinoid pan inverse agonist of the retinoic acid receptors. 6:618-627. 2011
- Metabolic labeling of fucosylated glycans in developing zebrafish. 6:547-552. 2011
- Binding and pK(a) modulation of a polycyclic substrate analogue in a type II polyketide acyl carrier protein. 6:413-418. 2011
- Development and use of clickable activity based protein profiling agents for protein arginine deiminase 4. 6:466-476. 2011
- Selective inactivation of a human neuronal silencing phosphatase by a small molecule inhibitor. 6:511-519. 2011
- Identification of SR3335 (ML-176): a synthetic RORα selective inverse agonist. 6:218-222. 2011
- Identification of SR8278, a synthetic antagonist of the nuclear heme receptor REV-ERB. 6:131-134. 2011
- Symptomatic relief of botulinum neurotoxin/a intoxication with aminopyridines: A new twist on an old molecule. 5:1183-1191. 2010
- Trapping of hepatitis b virus capsid assembly intermediates by phenylpropenamide assembly accelerators. 5:1125-1136. 2010
- Identification of SR1078, a synthetic agonist for the orphan nuclear receptors RORα and RORγ. 5:1029-1034. 2010
- A general approach for receptor and antibody-targeted detection of native proteins utilizing split-luciferase reassembly. 5:943-952. 2010
- A novel and specific NADPH oxidase-1 (Nox1) small-molecule inhibitor blocks the formation of functional invadopodia in human colon cancer cells. 5:981-993. 2010
- Identification of a small molecule inhibitor of importin beta mediated nuclear import by confocal on-bead screening of tagged one-bead one-compound libraries. 5:967-979. 2010
- Development of GlcNAc-Inspired Iminocyclitiols as Potent and Selective N-Acetyl-beta-Hexosaminidase Inhibitors. 5:489-497. 2010
- Sceptrin, a marine natural compound, inhibits cell motility in a variety of cancer cell lines. 5:195-202. 2010
- Exploring disease through metabolomics. 5:91-103. 2010
- Orchestrating redox signaling networks through regulatory cysteine switches. 5:47-62. 2010
- An orthogonal active site identification system (OASIS) for proteomic profiling of natural product. 4:948-957. 2009
- Structure-activity analysis of semisynthetic nucleosomes: mechanistic insights into the stimulation of Dot1L by ubiquitylated histone H2B. 4:958-968. 2009
- Nosiheptide biosynthesis featuring a unique indole side ring formation on the characteristic thiopeptide framework. 4:855-864. 2009
- Novel flufenamic acid analogues as inhibitors of androgen receptor mediated transcription. 4:834-843. 2009
- Mining the thiol proteome for sulfenic acid modifications reveals new targets for oxidation in cells. 4:783-799. 2009
- Regulation of Alkyl-dihydrothiazole-carboxylates (ATCs) by Iron and the Pyochelin Gene Cluster in Pseudomonas aeruginosa. 4:617-623. 2009
- Antagonism of c-IAP and XIAP proteins is required for efficient induction of cell death by small-molecule IAP antagonists. 4:557-566. 2009
- Comparative assessment of large-scale proteomic studies of apoptotic proteolysis. 4:401-408. 2009
- My h-index turns 40: my midlife crisis of impact. 4:311-313. 2009
- Rational and modular design of potent ligands targeting the rna that causes myotonic dystrophy 2. 4:345-355. 2009
- Evaluating the potential for halogen bonding in the oxyanion hole of ketosteroid isomerase using unnatural amino acid mutagenesis. 4:269-273. 2009
- Small molecule microarrays of RNA-focused peptoids help identify inhibitors of a pathogenic group I intron. 4:299-307. 2009
- Alpha anomers of iGb3 and Gb3 stimulate cytokine production by natural killer T cells. 4:199-208. 2009
- Probing the function of heme distortion in the h-nox family. 3:703-710. 2008
- Chain dynamics of nascent polypeptides emerging from the ribosome. 3:555-566. 2008
- Ligand-binding pocket shape differences between sphingosine 1-phosphate (S1P) receptors S1P1 and S1P3 determine efficiency of chemical probe identification by ultrahigh-throughput screening. 3:486-498. 2008
- Pathway engineered enzymatic de novo purine nucleotide synthesis. 3:499-511. 2008
- Discovery of selective aminothiazole aurora kinase inhibitors. 3:180-192. 2008
- Click imaging of biochemical processes in living systems. 2:775-778. 2007
- A small molecule microarray platform to select RNA internal loop-ligand interactions. 2:745-754. 2007
- Exploring the structural diversity of mammalian carbohydrates ("glycospace") by statistical databank analysis. 2:685-691. 2007
- Closing the gap between interdisciplinary research and disciplinary teaching. 2:518-520. 2007
- A genetically encoded metabolically stable analogue of phosphotyrosine in Escherichia coli. 2:474-478. 2007
- Structural basis for high-affinity peptide inhibition of human Pin1. 2:320-328. 2007
- A higher degree of difficulty. 2:197-199. 2007
- Identification and characterization of small-molecule inducers of epidermal keratinocyte differentiation. 2:171-175. 2007
- The old is new again: asparagine oxidation in calcium-dependent antibiotic biosynthesis. 2:152-154. 2007
- Balancing teaching and research in obtaining a faculty position at a predominantly undergraduate institution. 2:521-524. 2007
- Biosynthetic characterization and chemoenzymatic assembly of the cryptophycins. Potent anticancer agents from Nostoc cyanobionts. 1:766-779. 2006
- Chemical chaperones and permissive temperatures atter the cellular locatization of Gaucher disease associated glucocerebrosidase variants. 1:235-251. 2006
- Design and characterization of an active site selective caspase-3 transnitrosating agent. 1:659-665. 2006
- Histone citrullination by protein arginine deiminase: Is arginine methylation a green light or a roadblock?. 1:433-441. 2006
- Mechanism-based protein cross-linking probes to investigate carrier protein-mediated biosynthesis. 1:687-691. 2006
- The use of small molecules to investigate molecular mechanisms and therapeutic targets for treatment of botulinum neurotoxin A intoxication. 1:359-369. 2006
- Turning G proteins on and off using peptide ligands. 1:570-574. 2006
- Utilizing rna aptamers to probe a physiologically important heme-regulated cellular network. 1:515-524. 2006