recent publications

• academic article

  • Arunrungichian, K., Boonyarat, C., Fokin, V. V., Taylor, P., Vajragupta, O. Cognitive improvements in a mouse model with substituted 1,2,3-triazole agonists for nicotinic acetylcholine receptors ACS Chemical Neuroscience  2015 6:1331-1340  DOI:10.1021/acschemneuro.5b00059  PMID:25978789
  • Arunrungvichian, K., Fokin, V. V., Vajragupta, O., Taylor, P. Selectivity optimization of substituted 1,2,3-triazoles as α7 nicotinic acetylcholine receptor agonists ACS Chemical Neuroscience  2015 6:1317-1330  DOI:10.1021/acschemneuro.5b00058  PMID:25932897
  • Sanphanya, K., Wattanapitayakul, S. K., Phowichit, S., Fokin, V. V., Vajragupta, O. Novel VEGFR-2 kinase inhibitors identified by the back-to-front approach Bioorganic & Medicinal Chemistry Letters  2013 23:2962-2967  DOI:10.1016/j.bmcl.2013.03.042  PMID:23562241  PMCID:PMC3942623
  • Jiaranaikulwanitch, J., Govitrapong, P., Fokin, V. V., Vajragupta, O. From BACE1 inhibitor to multifunctionality of tryptoline and tryptamine triazole derivatives for Alzheimer's disease Molecules  2012 17:8312-8333  DOI:10.3390/molecules17078312  PMID:22781443  PMCID:PMC3618987
  • Sanphanya, K., Wattanapitayakul, S. K., Prangsaengtong, O., Jo, M., Koizumi, K., Shibahara, N., Priprem, A., Fokin, V. V., Vajragupta, O. Synthesis and evaluation of 1-(substituted)-3-prop-2-ynylureas as antiangiogenic agents Bioorganic & Medicinal Chemistry Letters  2012 22:3001-3005  DOI:10.1016/j.bmcl.2012.02.029  PMID:22414612
  • Rojsanga, P., Boonyarat, C., Utsintong, M., Nemecz, A., Yamauchi, J. G., Talley, T. T., Olson, A. F., Matsumoto, K., Vajragupta, O. The effect of crebanine on memory and cognition impairment via the alpha-7 nicotinic acetylcholine receptor Life Sciences  2012 91:107-114  DOI:10.1016/j.lfs.2012.06.017  PMID:22749860
  • Utsintong, M., Rojsanga, P., Ho, K. Y., Talley, T. T., Olson, A. J., Matsumoto, K., Vajragupta, O. Virtual screening against acetylcholine binding protein Journal of Biomolecular Screening  2012 17:204-215  DOI:10.1177/1087057111421667  PMID:21956172  PMCID:PMC4762448
  • Jiaranaikulwanitch, J., Boonyarat, C., Fokin, V. V., Vajragupta, O. Triazolyl tryptoline derivatives as beta-secretase inhibitors Bioorganic & Medicinal Chemistry Letters  2010 20:6572-6576  DOI:10.1016/j.bmcl.2010.09.043  PMID:20943389  PMCID:PMC3055559
  • Utsintong, M., Kaewnoi, A., Leelamanit, W., Olson, A. J., Vajragupta, O. Rediocides A and G as potential antitoxins against cobra venom Chemistry & Biodiversity  2009 6:1404-1414  DOI:10.1002/cbdv.200800204  PMID:19774596
  • Utsintong, M., Talley, T. T., Taylor, P. W., Olson, A. J., Vajragupta, O. Virtual screening against alpha-cobratoxin Journal of Biomolecular Screening  2009 14:1109-1118  DOI:10.1177/1087057109344617  PMID:19734437  PMCID:PMC3191909
  • Vajragupta, O., Boonyarat, C., Murakami, Y., Tohda, M., Musatmoto, K., Olson, A. J., Watanabe, H. A novel neuroprotective agent with antioxidant and nitric oxide synthase inhibitory action Free Radical Research  2006 40:685-695  DOI:10.1080/10715760500423763  PMID:16983995
  • Vajragupta, O., Boonchoong, P., Morris, G. M., Olson, A. J. Active site binding modes of curcumin in HIV-1 protease and integrase Bioorganic & Medicinal Chemistry Letters  2005 15:3364-3368  DOI:10.1016/j.bmcl.2005.05.032  PMID:15950462