recent publications

• academic article

  • Franceschini, N., Fox, E., Zhang, Z., Edwards, T. L., Nalls, M. A., Sung, Y. J., Tayo, B. O., Sun, Y. V., Gottesman, O., Adeyemo, A., Johnson, A. D., Young, J. H., et al. Genome-wide association analysis of blood-pressure traits in African-ancestry individuals reveals common associated genes in African and non-African populations American Journal of Human Genetics  2013 93:545-554  DOI:10.1016/j.ajhg.2013.07.010  PMID:23972371  PMCID:PMC3769920
  • Lee, S. H., Ripke, S., Neale, B. M., Faraone, S. V., Purcell, S. M., Perlis, R. H., Mowry, B. J., Thapar, A., Goddard, M. E., Witte, J. S., Absher, D., Agartz, I., et al. Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs Nature Genetics  2013 45:984-994  DOI:10.1038/ng.2711  PMID:23933821  PMCID:PMC3800159
  • Ganesh, S. K., Tragante, V., Guo, W., Guo, Y. R., Lanktree, M. B., Smith, E. N., Johnson, T., Castillo, B. A., Barnard, J., Baumert, J., Chang, Y. P. C., Elbers, C. C., et al. Loci influencing blood pressure identified using a cardiovascular gene-centric array Human Molecular Genetics  2013 22:1663-1678  DOI:10.1093/hmg/dds555  PMID:23303523  PMCID:PMC3657476
  • Ellinor, P. T., Lunetta, K. L., Glazer, N. L., Pfeufer, A., Alonso, A., Chung, M. K., Sinner, M. F., de Bakker, P. I. W., Mueller, M., Lubitz, S. A., Fox, E., Darbar, D., et al. Common variants in kcnn3 are associated with lone atrial fibrillation Nature Genetics  2010 42:240-244  DOI:10.1038/ng.537  PMID:20173747  PMCID:PMC2871387
  • Frazer, K. A., Ballinger, D. G., Cox, D. R., Hinds, D. A., Stuve, L. L., Gibbs, R. A., Belmont, J. W., Boudreau, A., Hardenbol, P., Leal, S. M., Pasternak, S., Wheeler, D. A., et al. A second generation human haplotype map of over 3.1 million SNPs Nature  2007 449:851-861  DOI:10.1038/nature06258  PMID:17943122  PMCID:PMC2689609
  • Sabeti, P. C., Varilly, P., Fry, B., Lohmueller, J., Hostetter, E., Cotsapas, C., Xie, X. H., Byrne, E. H., McCarroll, S. A., Gaudet, R., Schaffner, S. F., Lander, E. S. Genome-wide detection and characterization of positive selection in human populations Nature  2007 449:913-918  DOI:10.1038/nature06250  PMID:17943131  PMCID:PMC2687721
  • Wen, G., Wessel, J., Zhou, W., Ehret, G. B., Rao, F., Stridsberg, M., Mahata, S. K., Gent, P. M., Das, M., Cooper, R. S., Chakravarti, A., Zhou, H., et al. An ancestral variant of secretogranin ii confers regulation by phox2 transcription factors and association with hypertension Human Molecular Genetics  2007 16:1752-1764  DOI:10.1093/hmg/ddm123  PMID:17584765  PMCID:PMC2695823
  • Gu, C. C., Hunt, S. C., Kardia, S., Turner, S. T., Chakravarti, A., Schork, N., Olshen, R., Curb, D., Jaquish, C., Boerwinkle, E., Rao, D. C. An investigation of genome-wide associations of hypertension with microsatellite markers in the family blood pressure program (fbpp) Human Genetics  2007 121:577-590  DOI:10.1007/s00439-007-0349-8  PMID:17372766
  • Bibikova, M., Chudin, E., Wu, B., Zhou, L. X., Garcia, E. W., Liu, Y., Shin, S., Plaia, T. W., Auerbach, J. M., Arking, D. E., Gonzalez, R., Crook, J., et al. Human embryonic stem cells have a unique epigenetic signature Genome Research  2006 16:1075-1083  DOI:10.1101/gr.5319906  PMID:16899657  PMCID:PMC1557765
  • Chang, Y. P. C., Kim, J. D. O., Schwander, K., Rao, D. C., Miller, M. B., Weder, A. B., Cooper, R. S., Schork, N. J., Province, M. A., Morrison, A. C., Kardia, S. L., Quertermous, T., et al. The impact of data quality on the identification of complex disease genes: Experience from the family blood pressure program European Journal of Human Genetics  2006 14:469-477  DOI:10.1038/sj.ejhg.5201582  PMID:16493446
  • Altshuler, D., Brooks, L. D., Chakravarti, A., Collins, F. S., Daly, M. J., Donnelly, P., Gibbs, R. A., Belmont, J. W., Boudreau, A., Leal, S. M., Hardenbol, P., Pasternak, S., et al. A haplotype map of the human genome Nature  2005 437:1299-1320  DOI:10.1038/nature04226  PMID:16255080  PMCID:PMC1880871
  • Powell, D., Shen, Y., Tsui, L. C., Kruglyak, S., Royal, C. D. M., Nakamura, Y., Tanaka, Y., Jasperse, M., Belmont, J. W., Terry, S. F., Phillips, M. S., Lander, E. S., et al. The International HapMap project Nature  2003 426:789-796  DOI:10.1038/nature02168  PMID:14685227
  • Thiel, B. A., Chakravarti, A., Cooper, R. S., Luke, A., Lewis, S., Lynn, A., Tiwari, H., Schork, N. J., Weder, A. B. A genome-wide linkage analysis investigating the determinants of blood pressure in whites and african americans American Journal of Hypertension  2003 16:151-153  DOI:10.1016/s0895-7061(02)03246-6  PMID:12559684
  • Nath, S. K., Chakravarti, A., Chen, C. H., Cooper, R., Weder, A., Schork, N. J. Segregation analysis of blood pressure and body mass index in a rural us community Human Biology  2002 74:11-23  DOI:10.1353/hub.2002.0010  PMID:11931572
  • Boerwinkle, E., Brown, C. A., Carrejo, M., Ferrell, R., Hanis, C., Hutchinson, R., Kardia, S., Sing, C., Turner, S., Weder, A., Chakravarti, A., Cooper, R., et al. Multi-center genetic study of hypertension - the family blood pressure program (fbpp) Hypertension  2002 39:3-9  PMID:11799070
  • Schork, N. J., Nath, S. K., Fallin, D., Chakravarti, A. Linkage disequilibrium analysis of biallelic DNA markers, human quantitative trait loci, and threshold-defined case and control subjects American Journal of Human Genetics  2000 67:1208-1218  DOI:10.1086/321201  PMID:11032785  PMCID:PMC1288563
  • Schork, N. J., Chakravarti, A., Thiel, B., Fornage, M., Jacob, H. J., Cai, R., Rotimi, C. N., Cooper, R. S., Weder, A. B. Lack of association between a biallelic polymorphism in the adducin gene and blood pressure in whites and african americans American Journal of Hypertension  2000 13:693-698  DOI:10.1016/s0895-7061(00)00237-5  PMID:10912755
  • Jonsson, E. G., Nimgaonkar, V. L., Zhang, X. R., Shaw, S. H., Burgert, E., Crocq, M. A., Chakravarti, A., Sedvall, G. C. Trend for an association between schizophrenia and d3s1310, a marker in proximity to the dopamine d3 receptor gene American Journal of Medical Genetics  1999 88:352-357  DOI:10.1002/(sici)1096-8628(19990820)88:4<352::aid-ajmg12>3.3.co;2-s  PMID:10402502
  • Shaw, S. H., Carrasquillo, M. M., Kashuk, C., Puffenberger, E. G., Chakravarti, A. Allele frequency distributions in pooled DNA samples: Applications to mapping complex disease genes Genome Research  1998 8:111-123  PMID:9477339
  • Puffenberger, E. G., Hosoda, K., Washington, S. S., Nakao, K., Dewit, D., Yanagisawa, M., Chakravarti, A. A missense mutation of the endothelin-b receptor gene in multigenic hirschsprungs-disease Cell  1994 79:1257-1266  DOI:10.1016/0092-8674(94)90016-7  PMID:8001158
  • Puffenberger, E. G., Kauffman, E. R., Bolk, S., Matise, T. C., Washington, S. S., Angrist, M., Weissenbach, J., Garver, K. L., Mascari, M., Ladda, R., Slaugenhaupt, S. A., Chakravarti, A. Identity-by-descent and association mapping of a recessive gene for hirschsprung disease on human-chromosome 13q22 Human Molecular Genetics  1994 3:1217-1225  PMID:7987295
  • Washington, S. S., Bowcock, A. M., Gerken, S., Matsunami, N., Lesh, D., Osbornelawrence, S. L., Cowell, J., Ledbetter, D. H., White, R. L., Chakravarti, A. A somatic-cell hybrid map of human-chromosome-13 Genomics  1993 18:486-495  PMID:8307557
  • Winokur, S. T., Schutte, B., Weiffenbach, B., Washington, S. S., McElligott, D., Chakravarti, A., Wasmuth, J. H., Altherr, M. R. A radiation hybrid map of 15-loci on the distal long arm of chromosome-4, the region containing the gene responsible for facioscapulohumeral muscular-dystrophy (fshd) American Journal of Human Genetics  1993 53:874-880  PMID:8213815  PMCID:PMC1682402
  • Angrist, M., Kauffman, E., Slaugenhaupt, S. A., Matise, T. C., Puffenberger, E. G., Washington, S. S., Lipson, A., Cass, D. T., Reyna, T., Weeks, D. E., Sieber, W., Chakravarti, A. A gene for hirschsprung disease (megacolon) in the pericentromeric region of human chromosome-10 Nature Genetics  1993 4:351-356  DOI:10.1038/ng0893-351  PMID:8401581
  • Nimgaonkar, V. L., Ganguli, R., Washington, S. S., Chakravarti, A. Schizophrenia and porphobilinogen deaminase gene polymorphisms - an association study Schizophrenia Research  1992 8:51-58  DOI:10.1016/0920-9964(92)90060-i  PMID:1358185
  • Spielvogel, H., Hennies, H. C., Claussen, U., Washington, S. S., Chakravarti, A., Reis, A. Band-specific localization of the microsatellite at d13s71 by microdissection and enzymatic amplification American Journal of Human Genetics  1992 50:1031-1037  PMID:1570832