recent publications

• academic article

  • Kelly, J. W., Colon, W., Lai, Z., Lashuel, H. A., McCulloch, J., McCutchen, S. L., Miroy, G. J., Peterson, S. A. Transthyretin quaternary and tertiary structural changes facilitate misassembly into amyloid Advances in Protein Chemistry  1997 50:161-181  DOI:10.1016/s0065-3233(08)60321-6  PMID:9338081
  • Colon, W., Lai, Z., McCutchen, S. L., Miroy, G. J., Strang, C., Kelly, J. W. FAP mutations destabilize transthyretin facilitating conformational changes required for amyloid formation Ciba Foundation Symposium  1996 199:228-242  PMID:8915613
  • McCutchen, S. L., Lai, Z. H., Miroy, G. J., Kelly, J. W., Colon, W. Comparison of lethal and nonlethal transthyretin variants and their relationship to amyloid disease Biochemistry  1995 34:13527-13536  DOI:10.1021/bi00041a032  PMID:7577941
  • Graciani, N. R., Tsang, K. Y., McCutchen, S. L., Kelly, J. W. Amino acids that specify structure through hydrophobic clustering and histidine-aromatic interactions lead to biologically active peptidomimetics Bioorganic & Medicinal Chemistry  1994 2:999-1006  PMID:7712134
  • McCutchen, S. L., Kelly, J. W. Intermolecular disulfide linkages are not required for transthyretin amyloid fibril formation in vitro Biochemical and Biophysical Research Communications  1993 197:415-421  DOI:10.1006/bbrc.1993.2495  PMID:8267575
  • McCutchen, S. L., Colon, W., Kelly, J. W. Transthyretin mutation Leu-55-Pro significantly alters tetramer stability and increases amyloidogenicity Biochemistry  1993 32:12119-12127  DOI:10.1021/bi00096a024  PMID:8218290