recent publications

• academic article

  • Chen, Z., Cheng, K., Walton, Z., Wang, Y. C., Ebi, H., Shimamura, T., Liu, Y., Tupper, T., Ouyang, J., Li, J., Gao, P., Woo, M. S., et al. A murine lung cancer co-clinical trial identifies genetic modifiers of therapeutic response Nature  2012 483:613-617  DOI:10.1038/nature10937  PMID:22425996  PMCID:PMC3385933
  • de Graaf, C., Kooistra, A. J., Vischer, H. F., Katritch, V., Kuijer, M., Shiroishi, M., Iwata, S., Shimamura, T., Stevens, R. C., de Esch, I. J. P., Leurs, R. Crystal structure-based virtual screening for fragment-like ligands of the human histamine H(1) receptor Journal of Medicinal Chemistry  2011 54:8195-8206  DOI:10.1021/jm2011589  PMID:22007643  PMCID:PMC3228891
  • Shimamura, T., Shiroishi, M., Weyand, S., Tsujimoto, H., Winter, G., Katritch, V., Abagyan, R., Cherezov, V., Liu, W., Han, G. W., Kobayashi, T., Stevens, R. C., et al. Structure of the human histamine h(1) receptor complex with doxepin Nature  2011 475:65-70  DOI:10.1038/nature10236  PMID:21697825  PMCID:PMC3131495