recent publications

• academic article

  • Melet, A., Marques-Soares, C., Schoch, G. A., Macherey, A. C., Jaouen, M., Dansette, P. M., Sari, M. A., Johnson, E. F., Mansuy, D. Analysis of human cytochrome P4502C8 substrate specificity using a substrate pharmacophore and site-directed mutants Biochemistry  2004 43:15379-15392  DOI:10.1021/bi0489309  PMID:15581350
  • Wester, M. R., Johnson, E. F., Marques-Soares, C., Dansette, P. M., Mansuy, D., Stout, C. D. Structure of a substrate complex of mammalian cytochrome P450 2C5 at 2.3 A resolution: evidence for multiple substrate binding modes Biochemistry  2003 42:6370-6379  DOI:10.1021/bi0273922  PMID:12767218
  • Wester, M. R., Johnson, E. F., Marques-Soares, C., Dijols, S., Dansette, P. M., Mansuy, D., Stout, C. D. Structure of mammalian cytochrome P450 2C5 complexed with diclofenac at 2.1 A resolution: evidence for an induced fit model of substrate binding Biochemistry  2003 42:9335-9345  DOI:10.1021/bi0345561  PMID:12899620
  • Marques-Soares, C., Dijols, S., Macherey, A. C., Wester, M. R., Johnson, E. F., Dansette, P. M., Mansuy, D. Sulfaphenazole derivatives as tools for comparing cytochrome P450 2C5 and human cytochromes P450 2Cs: identification of a new high affinity substrate common to those enzymes Biochemistry  2003 42:6363-6369  DOI:10.1021/bi027391+  PMID:12767217