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Higher order iminodiacetic acid libraries for probing protein-protein interactions

Academic Article
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Overview

related to degree

  • Goldberg, Joel, Ph.D. in Chemistry, Scripps Research 1994 - 2000

authors

  • Boger, Dale
  • Ducray, P.
  • Chai, W. Y.
  • Jiang, W. Q.
  • Goldberg, Joel

publication date

  • September 1998

journal

  • Bioorganic & Medicinal Chemistry Letters  Journal

abstract

  • Higher order iminodiacetic acid diamide trimer (560 compounds) and tetramer libraries (1260 compounds) are described and were assembled in a convergent multistep solution-phase synthesis for use in studying protein-protein interactions.

subject areas

  • Chelating Agents
  • Databases as Topic
  • Dimerization
  • Drug Design
  • Imino Acids
  • Indicators and Reagents
  • Ligands
  • Molecular Conformation
  • Molecular Structure
  • Proteins
  • Structure-Activity Relationship
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Identity

International Standard Serial Number (ISSN)

  • 0960-894X

Digital Object Identifier (DOI)

  • 10.1016/s0960-894x(98)00423-5

PubMed ID

  • 9873538
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Additional Document Info

start page

  • 2339

end page

  • 2344

volume

  • 8

issue

  • 17

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