recent publications

• academic article

  • Berger, J. S., Elliott, L., Gallup, D., Roe, M., Granger, C. B., Armstrong, P. W., Simes, R. J., White, H. D., Van de Werf, F., Topol, E. J., Hochman, J. S., Newby, L. K., et al. Sex differences in mortality following acute coronary syndromes JAMA-Journal of the American Medical Association  2009 302:874-882  DOI:10.1001/jama.2009.1227  PMID:19706861  PMCID:PMC2778841
  • Aronow, H. D., Califf, R. M., Harrington, R. A., Vallee, M., Graffagnino, C., Shuaib, A., Fitzgerald, D. J., Easton, J. D., Van de Werf, F., Diener, H. C., Ferguson, J., Koudstaal, P. J., et al. Relation between aspirin dose, all-cause mortality, and bleeding in patients with recent cerebrovascular or coronary ischemic events (from the bravo trial) American Journal of Cardiology  2008 102:1285-1290  DOI:10.1016/j.amjcard.2008.07.019  PMID:18993142
  • Aronow, H. D., Lincoff, A. M., Quinn, M. J., McRae, A. T., Gurm, H. S., Houghtaling, P. L., Granger, C. B., Harrington, R. A., de Werf, F. V., Topol, E. J., Lauer, M. S., Gusto, Ilb Relation between previous lipid-lowering therapy and infaret size (creatine kinase-mb level) in patients presenting with acute myocardial infarction American Journal of Cardiology  2008 102:1119-1124  DOI:10.1016/j.amjcard.2008.06.032  PMID:18940276
  • Mahaffey, K. W., Roe, M. T., Kilaru, R., Alexander, J. H., Van de Werf, F., Califf, R. M., Simoons, M. L., Topol, E. J., Harrington, R. A. Creatine kinase-mb elevation after coronary artery bypass grafting surgery in patients with non-st-segment elevation acute coronary syndromes predict worse outcomes: Results from four large clinical trials European Heart Journal  2007 28:425-432  DOI:10.1093/eurheartj/ehl483  PMID:17267458
  • Galla, J. M., Mahaffey, K. W., Sapp, S. K., Alexander, J. H., Roe, M. T., Ohman, E. M., Granger, C. B., Armstrong, P. W., Harrington, R. A., White, H. D., Simoons, M. L., Newby, L. K., et al. Elevated creatine kinase-mb with normal creatine kinase predicts worse outcomes in patients with acute coronary syndromes: Results from 4 large clinical trials American Heart Journal  2006 151:16-24  DOI:10.1016/j.ahj.2005.01.045  PMID:16368286
  • Exaire, J. E., Butman, S. M., Ebrahimi, R., Kleiman, N. S., Harrington, R. A., Schweiger, M. J., Bittl, J. A., Wolski, K., Topol, E. J., Lincoff, A. M., Invest, Replace- Provisional glycoprotein iib/iiia blockade in a randomized investigation of bivalirudin versus heparin plus planned glycoprotein iib/iiia inhibition during percutaneous coronary intervention: Predictors and outcome in the randomized evaluation in percutaneous coronary intervention linking angiomax to reduced clinical events (replace)-2 trial American Heart Journal  2006 152:157-162  DOI:10.1016/j.ahj.2005.09.004  PMID:16824849
  • Bushnell, C. D., Griffin, J., Newby, L. K., Goldstein, L. B., Mahaffey, K. W., Graffagnino, C. A., Harrington, R. A., White, H. D., Simes, R. J., Califf, R. M., Topol, E. J., Easton, J. D. Statin use and sex-specific stroke outcomes in patients with vascular disease Stroke  2006 37:1427-1431  DOI:10.1161/01.STR.0000221315.60282.ca  PMID:16645137
  • Saw, J., Bhatt, D. L., Moliterno, D. J., Brener, S. J., Steinhubl, S. R., Lincoff, A. M., Tcheng, J. E., Harrington, R. A., Simoons, M., Hu, T., Sheikh, M. A., Kereiakes, D. J., et al. The influence of peripheral arterial disease on outcomes - a pooled analysis of mortality in eight large randomized percutaneous coronary intervention trials Journal of the American College of Cardiology  2006 48:1567-1572  DOI:10.1016/j.jacc.2006.03.067  PMID:17045889
  • Mahaffey, K. W., Roe, M. T., Kilaru, R., French, J. K., Alexander, J. H., Berdan, L. G., Van De Werf, F., Simoons, M. L., Weaver, W. D., White, H. D., Lincoff, A. M., Kleiman, N. S., et al. Characterization of myocardial infarction as an end point in two large trials of acute coronary syndromes American Journal of Cardiology  2005 95:1404-1408  DOI:10.1016/j.amjcard.2005.02.005  PMID:15950560
  • Rebeiz, A. G., Johanson, P., Green, C. L., Crater, S. W., Roe, M. T., Langer, A., Giugliano, R. P., Lincoff, A. M., Newby, L. K., Harrington, R. A., Topol, E. J., Califf, R. M., et al. Comparison of st-segment resolution with combined fibrinolytic and glycoprotein iib/iiia inhibitor therapy versus fibrinolytic alone (data from four clinical trials) American Journal of Cardiology  2005 95:611-614  DOI:10.1016/j.amjcard.2004.10.038  PMID:15721101
  • Labinaz, M., Mathias, J., Pieper, K., Granger, C. B., Lincoff, A. M., Moliterno, D. J., Van de Werf, F., Simes, J., White, H. D., Simoons, M. L., Califf, R. M., Topol, E. J., et al. Outcomes of patients with acute coronary syndromes and prior percutaneous coronary intervention: A pooled analysis of three randomized clinical trials European Heart Journal  2005 26:128-136  DOI:10.1093/eurheartj/ehi061  PMID:15618068
  • Gurm, H. S., Sarembock, I. J., Kereiakes, D. J., Young, J. J., Harrington, R. A., Kleiman, N., Feit, F., Wolski, K., Bittl, J. A., Wilcox, R., Topol, E. J., Lincoff, A. M., et al. Use of bivalirudin during percutaneous coronary intervention in patients with diabetes mellitus - an analysis from the randomized evaluation in percutaneous coronary intervention linking angiomax to reduced clinical events (replace)-2 trial Journal of the American College of Cardiology  2005 45:1932-1938  DOI:10.1016/j.jacc.2005.02.074  PMID:15963389
  • Quinn, M. J., Aronow, H. D., Calif, R. M., Bhatt, D. L., Sapp, S., Kleiman, N. S., Harrington, R. A., Kong, D. F., Kandzari, D. E., Topol, E. J. Aspirin dose and six-month outcome after an acute coronary syndrome Journal of the American College of Cardiology  2004 43:972-978  DOI:10.1016/j.jacc.2003.09.059  PMID:15028352
  • Lincoff, A. M., Bittl, J. A., Kleiman, N. S., Sarembock, I. J., Jackman, J. D., Mehta, S., Tannenbaum, M. A., Niederman, A. L., Bachinsky, W. B., Tift-Mann, J., Parker, H. G., Kereiakes, D. J., et al. Comparison of bivalirudin versus heparin during percutaneous coronary intervention (the randomized evaluation of pci linking angiomax to reduced clinical events replace -1 trial) American Journal of Cardiology  2004 93:1092-1096  DOI:10.1016/j.amjcard.2004.01.033  PMID:15110198
  • Roe, M. T., Mahaffey, K. W., Kilaru, R., Alexander, J. H., Akkerhuis, K. M., Simoons, M. L., Harrington, R. A., Tardiff, B. E., Granger, C. B., Ohman, E. M., Moliterno, D. J., Lincoff, A. M., et al. Creatine kinase-mb elevation after percutaneous coronary intervention predicts adverse outcomes in patients with acute coronary syndromes European Heart Journal  2004 25:313-321  DOI:10.1016/j.ehj.2003.12.009  PMID:14984920
  • Rao, S. V., Jollis, J. G., Harrington, R. A., Granger, C. B., Newby, L. K., Armstrong, P. W., Moliterno, D. J., Lindblad, L., Pieper, K., Topol, E. J., Stamler, J. S., Califf, R. M. Relationship of blood transfusion and clinical outcomes in patients with acute coronary syndromes JAMA-Journal of the American Medical Association  2004 292:1555-1562  DOI:10.1001/jama.292.13.1555  PMID:15467057
  • Yen, M. H., Bhatt, D. L., Chew, D. P., Harrington, R. A., Newby, L. K., Ardissino, D., Van de Werf, F., White, J. A., Moliterno, D. J., Topol, E. J. Association between admission white blood cell count and one-year mortality in patients with acute coronary syndromes American Journal of Medicine  2003 115:318-321  DOI:10.1016/s0002-9343(03)00358-9  PMID:12967697
  • Lincoff, A. M., Bittl, J. A., Harrington, R. A., Feit, F., Kleiman, N. S., Jackman, J. D., Sarembock, I. J., Cohen, D. J., Spriggs, D., Ebrahimi, R., Keren, G., Carr, J., et al. Bivalirudin and provisional glycoprotein iib/iiia blockade compared with heparin and planned glycoprotein iib/iiia blockade during percutaneous coronary intervention - replace-2 randomized trial JAMA-Journal of the American Medical Association  2003 289:853-863  DOI:10.1001/jama.289.7.853  PMID:12588269
  • Bhatt, D. L., Chew, D. P., Lincoff, A. M., Simoons, M. L., Harrington, R. A., Ommen, S. R., Jia, G., Topol, E. J., Investigators, Pursuit Effect of revascularization on mortality associated with an elevated white blood cell count in acute coronary syndromes American Journal of Cardiology  2003 92:136-140  DOI:10.1016/s0002-9149(03)00527-7  PMID:12860213
  • Tolleson, T. R., Newby, L. K., Harrington, R. A., Bhapkar, M. V., Verheught, F. W. A., Berger, P. B., Moliterno, D. J., White, H. D., Ohman, E. M., Van de Werf, F., Topol, E. J., Califf, R. M., et al. Frequency of stent thrombosis after acute coronary syndromes (from the symphony and 2nd symphony trials) American Journal of Cardiology  2003 92:330-333  DOI:10.1016/s0002-9149(03)00641-6  PMID:12888148
  • Hasdai, D., Topol, E. J., Kilaru, R., Battler, A., Harrington, R. A., Vahanian, A., Ohman, E. M., Granger, C. B., Van de Werf, F., Simoons, M. L., O'Connor, C. M., Holmes, D. R. Frequency, patient characteristics, and, outcomes of mild-to-moderate heart failure complicating st-segment elevation acute myocardial infarction: Lessons from 4 international fibrinolytic therapy trials American Heart Journal  2003 145:73-79  DOI:10.1067/mhj.2003.53  PMID:12514657
  • Kong, D. F., Hasselblad, V., Harrington, R. A., White, H. D., Tcheng, J. E., Kandzari, D. E., Topol, E. J., Califf, R. M. Meta-analysis of survival with platelet glycoprotein IIb/IIIa antagonists for percutaneous coronary interventions American Journal of Cardiology  2003 92:651-655  DOI:10.1016/s002-9149(03)00816-6  PMID:12972100
  • Newby, L. K., Bhapkar, M. V., White, H. D., Topol, E. J., Dougherty, F. C., Harrington, R. A., Smith, M. C., Asarch, L. F., Califf, R. M., Investigators, Symphony, Investigators, 2nd Symphony Predictors of 90-day outcome in patients stabilized after acute coronary syndromes European Heart Journal  2003 24:172-181  DOI:10.1016/s0195-668x(03)00325-1  PMID:12573274
  • Khot, U. N., Jia, G., Moliterno, D. J., Lincoff, A. M., Khot, M. B., Harrington, R. A., Topol, E. J. Prognostic importance of physical examination for heart failure in non-st-elevation acute coronary syndromes - the enduring value of killip classification JAMA-Journal of the American Medical Association  2003 290:2174-2181  DOI:10.1001/jama.290.16.2174  PMID:14570953
  • Topol, E. J., Easton, D., Harrington, R. A., Amarenco, P., Califf, R. M., Graffagnino, C., Davis, S., Diener, H. C., Ferguson, J., Fitzgerald, D., Granett, J., Shuaib, A., et al. Randomized, double-blind, placebo-controlled, international trial of the oral iib/iiia antagonist lotrafiban in coronary and cerebrovascular disease Circulation  2003 108:399-406  DOI:10.1161/01.cir.0000084501.48570.f6  PMID:12874182
  • Kaul, P., Newby, L. K., Fu, Y. L., Hasselblad, V., Mahaffey, K. W., Christenson, R. H., Harrington, R. A., Ohman, E. M., Topol, E. J., Califf, R. M., Van de Werf, F., Armstrong, P. W., et al. Troponin t and quantitative st-segment depression offer complementary prognostic information in the risk stratification of acute coronary syndrome patients Journal of the American College of Cardiology  2003 41:371-380  DOI:10.1016/s0735-1097(02)02824-3  PMID:12575962
  • Newby, L. K., Harrington, R. A., Bhapkar, M. V., Van de Werf, F., Hochman, J. S., Granger, C. B., Simes, R. J., Davis, C. G., Topol, E. J., Califf, R. M., Moliterno, D. J., Investigators, PARAGON A An automated strategy for bedside aptt determination and unfractionated heparin infusion adjustment in acute coronary syndromes: Insights from paragon a Journal of Thrombosis and Thrombolysis  2002 14:33-42  DOI:10.1023/a:1022062204490  PMID:12652148
  • Breeman, A., Mercado, N., Lenzen, M., van den Brand, M. M. J., Harrington, R. A., Califf, R. M., Topol, E. J., Simoons, M. L., Boersma, E., Investigators, Pursuit Characteristics, treatment and outcome of patients with non-st-elevation acute coronary syndromes and multivessel coronary artery disease: Observations from pursuit (platelet glycoprotein iib/iiia in unstable angina: Receptor suppression using integrelin therapy) Cardiology  2002 98:195-201  DOI:10.1159/000067321  PMID:12566649
  • Ronner, E., Boersma, E., Laarman, G. J., Somsen, G. A., Harrington, R. A., Deckers, J. W., Topol, E. J., Califf, R. M., Simoons, M. L. Early angioplasty in acute coronary syndromes without persistent st-segment elevation improves outcome but increases the need for six-month repeat revascularization - an analysis of the pursuit trial Journal of the American College of Cardiology  2002 39:1924-1929  DOI:10.1016/s0735-1097(02)01897-1  PMID:12084589
  • Mahaffey, K. W., Roe, M. T., Dyke, C. K., Newby, L. K., Kleiman, N. S., Connolly, P., Berdan, L. G., Sparapani, R., Lee, K. L., Armstrong, P. W., Topol, E. J., Califf, R. M., et al. Misreporting of myocardial infarction end points: Results of adjudication by a central clinical events committee in the paragon-b trial American Heart Journal  2002 143:242-248  DOI:10.1067/mhj.2002.120145  PMID:11835026
  • Labinaz, M., Kilaru, R., Pieper, K., Marso, S. P., Kitt, M. M., Simoons, M. L., Califf, R. M., Topol, E. J., Armstrong, P. W., Harrington, R. A., Investigators, Pursuit Outcomes of patients with acute coronary syndromes and prior coronary artery bypass grafting - results from the platelet glycoprotein iib/iiia in unstable angina: Receptor suppression using integrilin therapy (pursuit) trial Circulation  2002 105:322-327  DOI:10.1161/hc0302.102578  PMID:11804987
  • Rooner, E., Boersma, E., Akkerhuis, K. M., Harrington, R. A., Lincoff, A. M., Deckers, J. W., Karsch, K., Kleiman, N. S., Vahanian, A., Topol, E. J., Califf, R. M., Simoons, M. L. Patients with acute coronary syndromes without persistent st elevation undergoing percutaneous coronary intervention benefit most from early intervention with protection by a glycoprotein iib/iiia receptor blocker European Heart Journal  2002 23:239-246  DOI:10.1053/euhj.2001.2736  PMID:11792139
  • Boersma, E., Harrington, R. A., Moliterno, D. J., White, H., Theroux, P., Van de Werf, F., de Torbal, A., Armstrong, P. W., Wallentin, L. C., Wilcox, R. G., Simes, J., Califf, R. M., et al. Platelet glycoprotein iib/iiia inhibitors in acute coronary syndromes: A meta-analysis of all major randomised clinical trials Lancet  2002 359:189-198  DOI:10.1016/s0140-6736(02)07442-1  PMID:11812552
  • Mukherjee, D., Mahaffey, K. W., Moliterno, D. J., Harrington, R. A., Yadav, J. S., Pieper, K. S., Gallup, D., Dyke, C., Roe, M. T., Berdan, L., Lauer, M. S., Manttari, M., et al. Promise of combined low-molecular-weight heparin and platelet glycoprotein iib/iiia inhibition: Results from platelet iib/iiia antagonist for the reduction of acute coronary syndrome events in a global organization network b (paragon b) American Heart Journal  2002 144:995-1002  DOI:10.1067/mhj.2002.126118  PMID:12486423
  • Al-Khatib, S. M., Granger, C. B., Huang, Y., Lee, K. L., Califf, R. M., Simoons, M. L., Armstrong, P. W., Van de Werf, F., White, H. D., Simes, R. J., Moliterno, D. J., Topol, E. J., et al. Sustained ventricular arrhythmias among patients with acute coronary syndromes with no st-segment elevation - incidence, predictors, and outcomes Circulation  2002 106:309-312  DOI:10.1161/01.cir.0000022692.49934.e3  PMID:12119245
  • Al-Khatib, S. M., Pieper, K. S., Lee, K. L., Mahaffey, K. W., Hochman, J. S., Pepine, C. J., Kopecky, S. L., Akkerhuis, M., Stepinska, J., Simoons, M. L., Topol, E. J., Califf, R. M., et al. Atrial fibrillation and mortality among patients with acute coronary syndromes without st-segment elevation: Results from the pursuit trial American Journal of Cardiology  2001 88:76-79  DOI:10.1016/s0002-9149(01)01593-4
  • Lauer, M. A., Houghtaling, P. L., Peterson, J. G., Granger, C. B., Bhatt, D. L., Sapp, S. K., Simoons, M. L., Harrington, R. A., Topol, E. J., Lincoff, A. M. Attenuation of rebound ischemia after discontinuation of heparin therapy by glycoprotein iib/iiia inhibition with eptifibatide in patients with acute coronary syndromes - observations from the platelet iib/iiia in unstable angina: Receptor suppression using integrilin therapy (pursuit) trial Circulation  2001 104:2772-2777  DOI:10.1161/hc4801.100358  PMID:11733393
  • Newby, L. K., Ohman, E. M., Christenson, R. H., Moliterno, D. J., Harrington, R. A., White, H. D., Armstrong, P. W., Van de Werf, F., Pfisterer, M., Hasselblad, V., Califf, R. M., Topol, E. J., et al. Benefit of glycoprotein iib/iiia inhibition in patients with acute coronary syndromes and troponin t-positive status - the paragon-b troponin t substudy Circulation  2001 103:2891-2896  DOI:10.1161/‚Äã01.CIR.103.24.2891  PMID:11413076
  • Mahaffey, K. W., Harrington, R. A., Akkerhuis, M., Kleiman, N. S., Berdan, L. G., Crenshaw, B. S., Tardiff, B. E., Granger, C. B., DeJong, I., Bhapkar, M., Widimsky, P., Corbalon, R., et al. Disagreements between central clinical events committee and site investigator assessments of myocardial infarction endpoints in an international clinical trial: Review of the pursuit study Current Controlled Trials in Cardiovascular Medicine  2001 2:187-194  DOI:10.1186/cvm-2-4-187  PMID:11806794  PMCID:PMC57750
  • Aronow, H. D., Topol, E. J., Roe, M. T., Houghtaling, P. L., Wolski, K. E., Lincoff, A. M., Harrington, R. A., Califf, R. M., Ohman, E. M., Kleiman, N. S., Keltai, M., Wilcox, R. G., et al. Effect of lipid-lowering therapy on early mortality after acute coronary syndromes: An observational study Lancet  2001 357:1063-1068  DOI:10.1016/s0140-6736(00)04257-4  PMID:11297956
  • Peterson, J. G., Topol, E. J., Roe, M. T., Sapp, S. K., Lincoff, A. M., Deckers, J. W., Blackstone, E. H., Harrington, R. A., Califf, R. M., Lauer, M. S., Investigators, Pursuit Prognostic importance of concomitant heparin with eptifibatide in acute coronary syndromes American Journal of Cardiology  2001 87:532-536  DOI:10.1016/s0002-9149(00)01426-0  PMID:11230834
  • Kaul, P., Fu, Y. L., Chang, W. C., Harrington, R. A., Wagner, G. S., Goodman, S. G., Granger, C. B., Moliterno, D. J., Van de Werf, F., Califf, R. N., Topol, E. J., Armstrong, P. W., et al. Prognostic value of st segment depression in acute coronary syndromes: Insights from paragon-a applied to gusto-iib Journal of the American College of Cardiology  2001 38:64-71  DOI:10.1016/s0735-1097(01)01307-9  PMID:11451297
  • Mahaffey, K. W., Harrington, R. A., Akkerhuis, M., Kleiman, N. S., Berdan, L. G., Crenshaw, B. S., Tardiff, B. E., Granger, C. B., DeJong, I., Bhapkar, M., Widimsky, P., Corbalon, R., et al. Systematic adjudication of myocardial infarction end-points in an international clinical trial Current Controlled Trials in Cardiovascular Medicine  2001 2:180-186  DOI:10.1186/cvm-2-4-180  PMID:11806793  PMCID:PMC57749
  • Greenbaum, A. B., Harrington, R. A., Hudson, M. P., MacAulay, C. M., Wilcox, R. G., Simoons, M. L., Berdan, L. G., Guerci, A., Cokkinos, D. V., Kitt, M. M., Lincoff, A. M., Topol, E. J., et al. Therapeutic value of eptifibatide at community hospitals transferring patients to tertiary referral centers early after admission for acute coronary syndromes Journal of the American College of Cardiology  2001 37:492-498  DOI:10.1016/s0735-1097(00)01143-8  PMID:11216968
  • Cohen, M. G., Pacchiana, C. M., Corbalan, R., Perez, J. E. I., Ponte, C. I., Oropeza, E. S., Diaz, R., Paolasso, E., Izasa, D., Rodas, M. A., Urrutia, C. E., Harrington, R. A., et al. Variation in patient management and outcomes for acute coronary syndromes in latin america and north america: Results from the platelet iib/iiia in unstable angina: Receptor suppression using integrilin therapy (pursuit) trial American Heart Journal  2001 141:391-401  DOI:10.1067/mhj.2001.113216  PMID:11231436
  • Hasdai, D., Holmes, D. R., Criger, D. A., Topol, E. J., Califf, R. M., Harrington, R. A., Pursuit Trial ,Investigators Age and outcome after acute coronary syndromes without persistent st-segment elevation American Heart Journal  2000 139:858-866  DOI:10.1016/s0002-8703(00)90018-8  PMID:10783220
  • Alexander, J. H., Sparapani, R. A., Mahaffey, K. W., Deckers, J. W., Newby, L. K., Ohman, E. M., Corbalan, R., Chierchia, S. L., Boland, J. B., Simoons, M. L., Califf, R. M., Topol, E. J., et al. Association between minor elevations of creatine kinase-mb level and mortality in patients with acute coronary syndromes without st-segment elevation JAMA-Journal of the American Medical Association  2000 283:347-353  DOI:10.1001/jama.283.3.347  PMID:10647797
  • Hasdai, D., Holmes, D. R., Criger, D. A., Topol, E. J., Califf, R. M., Wilcox, R. G., Paolasso, E., Simoons, M., Deckers, J., Harrington, R. A., investigators, Pursuit trial Cigarette smoking status and outcome among patients with acute coronary syndromes without persistent st-segment elevation: Effect of inhibition of platelet glycoprotein iib/iiia with eptifibatide American Heart Journal  2000 139:454-460  DOI:10.1067/mhj.2000.103847  PMID:10689260
  • Roe, M. T., Harrington, R. A., Prosper, D. M., Pieper, K. S., Bhatt, D. L., Lincoff, A. M., Simoons, M. L., Akkerhuis, M., Ohman, E. M., Kitt, M. M., Vahanian, A., Ruzyllo, W., et al. Clinical and therapeutic profile of patients presenting with acute coronary syndromes who do not have significant coronary artery disease Circulation  2000 102:1101-1106  PMID:10973837
  • Topol, C. E., Califf, R. M., Simes, R. J., Van de Werf, F., Diaz, R., Paolasso, E., Aylward, P. E., Keech, A., Klein, W., Piegas, L., Tomov, I., Armstrong, P. W., et al. Comparison of sibrafiban with aspirin for prevention of cardiovascular events after acute coronary syndromes: A randomised trial Lancet  2000 355:337-345  PMID:10665552
  • Mark, D. B., Harrington, R. A., Lincoff, A. M., Califf, R. M., Nelson, C. L., Tsiatis, A. A., Buell, H., Mahaffey, K. W., Davidson-Ray, L., Topol, E. J. Cost-effectiveness of platelet glycoprotein IIb/IIIa inhibition with eptifibatide in patients with non-ST-elevation acute coronary syndromes Circulation  2000 101:366-371  PMID:10653826
  • Harrington, R. A., Armstrong, P. W., Graffagnino, C., Van de Werf, F., Kereiakes, D. J., Sigmon, K. N., Card, T., Joseph, D. M., Samuels, R., Granett, J., Chan, R., Califf, R. M., et al. Dose-finding, safety, and tolerability study of an oral platelet glycoprotein IIb/IIIa inhibitor, lotrafiban, in patients with coronary or cerebral atherosclerotic disease Circulation  2000 102:728-735  PMID:10942739
  • Kleiman, N. S., Lincoff, A. M., Flaker, G. C., Pieper, K. S., Wilcox, R. G., Berdan, L. G., Lorenz, T. J., Cokkinos, D. V., Simoons, M. L., Boersma, E., Topol, E. J., Califf, R. M., et al. Early percutaneous coronary intervention, platelet inhibition with eptifibatide, and clinical outcomes in patients with acute coronary syndromes Circulation  2000 101:751-757  PMID:10683348
  • Marso, S. P., Bhatt, D. L., Roe, M. T., Houghtaling, P. L., Labinaz, M., Kleiman, N. S., Dyke, C., Simmoons, M. L., Califf, R. M., Harrington, R. A., Topol, E. J., Investigators, Pursuit Enhanced efficacy of eptifibatide administration in patients with acute coronary syndrome requiring in-hospital coronary artery bypass grafting Circulation  2000 102:2952-2958  PMID:11113045
  • Akkerhuis, K. M., Deckers, J. W., Boersma, E., Harrington, R. A., Stepinska, J., Mahaffey, K. W., Wilcox, R. G., Lincoff, A. M., Keltai, M., Topol, E. J., Califf, R. M., Simoons, M. L., et al. Geographic variability in outcomes within an international trial of glycoprotein iib/iiia inhibition in patients with acute coronary syndromes - results from pursuit European Heart Journal  2000 21:371-381  DOI:10.1053/euhj.1999.1743  PMID:10666351
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