recent publications
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academic article
- Berger, J. S., Elliott, L., Gallup, D., Roe, M., Granger, C. B., Armstrong, P. W., Simes, R. J., White, H. D., Van de Werf, F., Topol, E. J., Hochman, J. S., Newby, L. K., et al. Sex differences in mortality following acute coronary syndromes JAMA-Journal of the American Medical Association 2009 302:874-882 DOI:10.1001/jama.2009.1227 PMID:19706861 PMCID:PMC2778841
- Aronow, H. D., Califf, R. M., Harrington, R. A., Vallee, M., Graffagnino, C., Shuaib, A., Fitzgerald, D. J., Easton, J. D., Van de Werf, F., Diener, H. C., Ferguson, J., Koudstaal, P. J., et al. Relation between aspirin dose, all-cause mortality, and bleeding in patients with recent cerebrovascular or coronary ischemic events (from the bravo trial) American Journal of Cardiology 2008 102:1285-1290 DOI:10.1016/j.amjcard.2008.07.019 PMID:18993142
- Aronow, H. D., Lincoff, A. M., Quinn, M. J., McRae, A. T., Gurm, H. S., Houghtaling, P. L., Granger, C. B., Harrington, R. A., de Werf, F. V., Topol, E. J., Lauer, M. S., Gusto, Ilb Relation between previous lipid-lowering therapy and infaret size (creatine kinase-mb level) in patients presenting with acute myocardial infarction American Journal of Cardiology 2008 102:1119-1124 DOI:10.1016/j.amjcard.2008.06.032 PMID:18940276
- Mahaffey, K. W., Roe, M. T., Kilaru, R., Alexander, J. H., Van de Werf, F., Califf, R. M., Simoons, M. L., Topol, E. J., Harrington, R. A. Creatine kinase-mb elevation after coronary artery bypass grafting surgery in patients with non-st-segment elevation acute coronary syndromes predict worse outcomes: Results from four large clinical trials European Heart Journal 2007 28:425-432 DOI:10.1093/eurheartj/ehl483 PMID:17267458
- Galla, J. M., Mahaffey, K. W., Sapp, S. K., Alexander, J. H., Roe, M. T., Ohman, E. M., Granger, C. B., Armstrong, P. W., Harrington, R. A., White, H. D., Simoons, M. L., Newby, L. K., et al. Elevated creatine kinase-mb with normal creatine kinase predicts worse outcomes in patients with acute coronary syndromes: Results from 4 large clinical trials American Heart Journal 2006 151:16-24 DOI:10.1016/j.ahj.2005.01.045 PMID:16368286
- Exaire, J. E., Butman, S. M., Ebrahimi, R., Kleiman, N. S., Harrington, R. A., Schweiger, M. J., Bittl, J. A., Wolski, K., Topol, E. J., Lincoff, A. M., Invest, Replace- Provisional glycoprotein iib/iiia blockade in a randomized investigation of bivalirudin versus heparin plus planned glycoprotein iib/iiia inhibition during percutaneous coronary intervention: Predictors and outcome in the randomized evaluation in percutaneous coronary intervention linking angiomax to reduced clinical events (replace)-2 trial American Heart Journal 2006 152:157-162 DOI:10.1016/j.ahj.2005.09.004 PMID:16824849
- Bushnell, C. D., Griffin, J., Newby, L. K., Goldstein, L. B., Mahaffey, K. W., Graffagnino, C. A., Harrington, R. A., White, H. D., Simes, R. J., Califf, R. M., Topol, E. J., Easton, J. D. Statin use and sex-specific stroke outcomes in patients with vascular disease Stroke 2006 37:1427-1431 DOI:10.1161/01.STR.0000221315.60282.ca PMID:16645137
- Saw, J., Bhatt, D. L., Moliterno, D. J., Brener, S. J., Steinhubl, S. R., Lincoff, A. M., Tcheng, J. E., Harrington, R. A., Simoons, M., Hu, T., Sheikh, M. A., Kereiakes, D. J., et al. The influence of peripheral arterial disease on outcomes - a pooled analysis of mortality in eight large randomized percutaneous coronary intervention trials Journal of the American College of Cardiology 2006 48:1567-1572 DOI:10.1016/j.jacc.2006.03.067 PMID:17045889
- Mahaffey, K. W., Roe, M. T., Kilaru, R., French, J. K., Alexander, J. H., Berdan, L. G., Van De Werf, F., Simoons, M. L., Weaver, W. D., White, H. D., Lincoff, A. M., Kleiman, N. S., et al. Characterization of myocardial infarction as an end point in two large trials of acute coronary syndromes American Journal of Cardiology 2005 95:1404-1408 DOI:10.1016/j.amjcard.2005.02.005 PMID:15950560
- Rebeiz, A. G., Johanson, P., Green, C. L., Crater, S. W., Roe, M. T., Langer, A., Giugliano, R. P., Lincoff, A. M., Newby, L. K., Harrington, R. A., Topol, E. J., Califf, R. M., et al. Comparison of st-segment resolution with combined fibrinolytic and glycoprotein iib/iiia inhibitor therapy versus fibrinolytic alone (data from four clinical trials) American Journal of Cardiology 2005 95:611-614 DOI:10.1016/j.amjcard.2004.10.038 PMID:15721101
- Labinaz, M., Mathias, J., Pieper, K., Granger, C. B., Lincoff, A. M., Moliterno, D. J., Van de Werf, F., Simes, J., White, H. D., Simoons, M. L., Califf, R. M., Topol, E. J., et al. Outcomes of patients with acute coronary syndromes and prior percutaneous coronary intervention: A pooled analysis of three randomized clinical trials European Heart Journal 2005 26:128-136 DOI:10.1093/eurheartj/ehi061 PMID:15618068
- Gurm, H. S., Sarembock, I. J., Kereiakes, D. J., Young, J. J., Harrington, R. A., Kleiman, N., Feit, F., Wolski, K., Bittl, J. A., Wilcox, R., Topol, E. J., Lincoff, A. M., et al. Use of bivalirudin during percutaneous coronary intervention in patients with diabetes mellitus - an analysis from the randomized evaluation in percutaneous coronary intervention linking angiomax to reduced clinical events (replace)-2 trial Journal of the American College of Cardiology 2005 45:1932-1938 DOI:10.1016/j.jacc.2005.02.074 PMID:15963389
- Quinn, M. J., Aronow, H. D., Calif, R. M., Bhatt, D. L., Sapp, S., Kleiman, N. S., Harrington, R. A., Kong, D. F., Kandzari, D. E., Topol, E. J. Aspirin dose and six-month outcome after an acute coronary syndrome Journal of the American College of Cardiology 2004 43:972-978 DOI:10.1016/j.jacc.2003.09.059 PMID:15028352
- Lincoff, A. M., Bittl, J. A., Kleiman, N. S., Sarembock, I. J., Jackman, J. D., Mehta, S., Tannenbaum, M. A., Niederman, A. L., Bachinsky, W. B., Tift-Mann, J., Parker, H. G., Kereiakes, D. J., et al. Comparison of bivalirudin versus heparin during percutaneous coronary intervention (the randomized evaluation of pci linking angiomax to reduced clinical events replace -1 trial) American Journal of Cardiology 2004 93:1092-1096 DOI:10.1016/j.amjcard.2004.01.033 PMID:15110198
- Roe, M. T., Mahaffey, K. W., Kilaru, R., Alexander, J. H., Akkerhuis, K. M., Simoons, M. L., Harrington, R. A., Tardiff, B. E., Granger, C. B., Ohman, E. M., Moliterno, D. J., Lincoff, A. M., et al. Creatine kinase-mb elevation after percutaneous coronary intervention predicts adverse outcomes in patients with acute coronary syndromes European Heart Journal 2004 25:313-321 DOI:10.1016/j.ehj.2003.12.009 PMID:14984920
- Rao, S. V., Jollis, J. G., Harrington, R. A., Granger, C. B., Newby, L. K., Armstrong, P. W., Moliterno, D. J., Lindblad, L., Pieper, K., Topol, E. J., Stamler, J. S., Califf, R. M. Relationship of blood transfusion and clinical outcomes in patients with acute coronary syndromes JAMA-Journal of the American Medical Association 2004 292:1555-1562 DOI:10.1001/jama.292.13.1555 PMID:15467057
- Yen, M. H., Bhatt, D. L., Chew, D. P., Harrington, R. A., Newby, L. K., Ardissino, D., Van de Werf, F., White, J. A., Moliterno, D. J., Topol, E. J. Association between admission white blood cell count and one-year mortality in patients with acute coronary syndromes American Journal of Medicine 2003 115:318-321 DOI:10.1016/s0002-9343(03)00358-9 PMID:12967697
- Lincoff, A. M., Bittl, J. A., Harrington, R. A., Feit, F., Kleiman, N. S., Jackman, J. D., Sarembock, I. J., Cohen, D. J., Spriggs, D., Ebrahimi, R., Keren, G., Carr, J., et al. Bivalirudin and provisional glycoprotein iib/iiia blockade compared with heparin and planned glycoprotein iib/iiia blockade during percutaneous coronary intervention - replace-2 randomized trial JAMA-Journal of the American Medical Association 2003 289:853-863 DOI:10.1001/jama.289.7.853 PMID:12588269
- Bhatt, D. L., Chew, D. P., Lincoff, A. M., Simoons, M. L., Harrington, R. A., Ommen, S. R., Jia, G., Topol, E. J., Investigators, Pursuit Effect of revascularization on mortality associated with an elevated white blood cell count in acute coronary syndromes American Journal of Cardiology 2003 92:136-140 DOI:10.1016/s0002-9149(03)00527-7 PMID:12860213
- Tolleson, T. R., Newby, L. K., Harrington, R. A., Bhapkar, M. V., Verheught, F. W. A., Berger, P. B., Moliterno, D. J., White, H. D., Ohman, E. M., Van de Werf, F., Topol, E. J., Califf, R. M., et al. Frequency of stent thrombosis after acute coronary syndromes (from the symphony and 2nd symphony trials) American Journal of Cardiology 2003 92:330-333 DOI:10.1016/s0002-9149(03)00641-6 PMID:12888148
- Hasdai, D., Topol, E. J., Kilaru, R., Battler, A., Harrington, R. A., Vahanian, A., Ohman, E. M., Granger, C. B., Van de Werf, F., Simoons, M. L., O'Connor, C. M., Holmes, D. R. Frequency, patient characteristics, and, outcomes of mild-to-moderate heart failure complicating st-segment elevation acute myocardial infarction: Lessons from 4 international fibrinolytic therapy trials American Heart Journal 2003 145:73-79 DOI:10.1067/mhj.2003.53 PMID:12514657
- Kong, D. F., Hasselblad, V., Harrington, R. A., White, H. D., Tcheng, J. E., Kandzari, D. E., Topol, E. J., Califf, R. M. Meta-analysis of survival with platelet glycoprotein IIb/IIIa antagonists for percutaneous coronary interventions American Journal of Cardiology 2003 92:651-655 DOI:10.1016/s002-9149(03)00816-6 PMID:12972100
- Newby, L. K., Bhapkar, M. V., White, H. D., Topol, E. J., Dougherty, F. C., Harrington, R. A., Smith, M. C., Asarch, L. F., Califf, R. M., Investigators, Symphony, Investigators, 2nd Symphony Predictors of 90-day outcome in patients stabilized after acute coronary syndromes European Heart Journal 2003 24:172-181 DOI:10.1016/s0195-668x(03)00325-1 PMID:12573274
- Khot, U. N., Jia, G., Moliterno, D. J., Lincoff, A. M., Khot, M. B., Harrington, R. A., Topol, E. J. Prognostic importance of physical examination for heart failure in non-st-elevation acute coronary syndromes - the enduring value of killip classification JAMA-Journal of the American Medical Association 2003 290:2174-2181 DOI:10.1001/jama.290.16.2174 PMID:14570953
- Topol, E. J., Easton, D., Harrington, R. A., Amarenco, P., Califf, R. M., Graffagnino, C., Davis, S., Diener, H. C., Ferguson, J., Fitzgerald, D., Granett, J., Shuaib, A., et al. Randomized, double-blind, placebo-controlled, international trial of the oral iib/iiia antagonist lotrafiban in coronary and cerebrovascular disease Circulation 2003 108:399-406 DOI:10.1161/01.cir.0000084501.48570.f6 PMID:12874182
- Kaul, P., Newby, L. K., Fu, Y. L., Hasselblad, V., Mahaffey, K. W., Christenson, R. H., Harrington, R. A., Ohman, E. M., Topol, E. J., Califf, R. M., Van de Werf, F., Armstrong, P. W., et al. Troponin t and quantitative st-segment depression offer complementary prognostic information in the risk stratification of acute coronary syndrome patients Journal of the American College of Cardiology 2003 41:371-380 DOI:10.1016/s0735-1097(02)02824-3 PMID:12575962
- Newby, L. K., Harrington, R. A., Bhapkar, M. V., Van de Werf, F., Hochman, J. S., Granger, C. B., Simes, R. J., Davis, C. G., Topol, E. J., Califf, R. M., Moliterno, D. J., Investigators, PARAGON A An automated strategy for bedside aptt determination and unfractionated heparin infusion adjustment in acute coronary syndromes: Insights from paragon a Journal of Thrombosis and Thrombolysis 2002 14:33-42 DOI:10.1023/a:1022062204490 PMID:12652148
- Breeman, A., Mercado, N., Lenzen, M., van den Brand, M. M. J., Harrington, R. A., Califf, R. M., Topol, E. J., Simoons, M. L., Boersma, E., Investigators, Pursuit Characteristics, treatment and outcome of patients with non-st-elevation acute coronary syndromes and multivessel coronary artery disease: Observations from pursuit (platelet glycoprotein iib/iiia in unstable angina: Receptor suppression using integrelin therapy) Cardiology 2002 98:195-201 DOI:10.1159/000067321 PMID:12566649
- Ronner, E., Boersma, E., Laarman, G. J., Somsen, G. A., Harrington, R. A., Deckers, J. W., Topol, E. J., Califf, R. M., Simoons, M. L. Early angioplasty in acute coronary syndromes without persistent st-segment elevation improves outcome but increases the need for six-month repeat revascularization - an analysis of the pursuit trial Journal of the American College of Cardiology 2002 39:1924-1929 DOI:10.1016/s0735-1097(02)01897-1 PMID:12084589
- Mahaffey, K. W., Roe, M. T., Dyke, C. K., Newby, L. K., Kleiman, N. S., Connolly, P., Berdan, L. G., Sparapani, R., Lee, K. L., Armstrong, P. W., Topol, E. J., Califf, R. M., et al. Misreporting of myocardial infarction end points: Results of adjudication by a central clinical events committee in the paragon-b trial American Heart Journal 2002 143:242-248 DOI:10.1067/mhj.2002.120145 PMID:11835026
- Labinaz, M., Kilaru, R., Pieper, K., Marso, S. P., Kitt, M. M., Simoons, M. L., Califf, R. M., Topol, E. J., Armstrong, P. W., Harrington, R. A., Investigators, Pursuit Outcomes of patients with acute coronary syndromes and prior coronary artery bypass grafting - results from the platelet glycoprotein iib/iiia in unstable angina: Receptor suppression using integrilin therapy (pursuit) trial Circulation 2002 105:322-327 DOI:10.1161/hc0302.102578 PMID:11804987
- Rooner, E., Boersma, E., Akkerhuis, K. M., Harrington, R. A., Lincoff, A. M., Deckers, J. W., Karsch, K., Kleiman, N. S., Vahanian, A., Topol, E. J., Califf, R. M., Simoons, M. L. Patients with acute coronary syndromes without persistent st elevation undergoing percutaneous coronary intervention benefit most from early intervention with protection by a glycoprotein iib/iiia receptor blocker European Heart Journal 2002 23:239-246 DOI:10.1053/euhj.2001.2736 PMID:11792139
- Boersma, E., Harrington, R. A., Moliterno, D. J., White, H., Theroux, P., Van de Werf, F., de Torbal, A., Armstrong, P. W., Wallentin, L. C., Wilcox, R. G., Simes, J., Califf, R. M., et al. Platelet glycoprotein iib/iiia inhibitors in acute coronary syndromes: A meta-analysis of all major randomised clinical trials Lancet 2002 359:189-198 DOI:10.1016/s0140-6736(02)07442-1 PMID:11812552
- Mukherjee, D., Mahaffey, K. W., Moliterno, D. J., Harrington, R. A., Yadav, J. S., Pieper, K. S., Gallup, D., Dyke, C., Roe, M. T., Berdan, L., Lauer, M. S., Manttari, M., et al. Promise of combined low-molecular-weight heparin and platelet glycoprotein iib/iiia inhibition: Results from platelet iib/iiia antagonist for the reduction of acute coronary syndrome events in a global organization network b (paragon b) American Heart Journal 2002 144:995-1002 DOI:10.1067/mhj.2002.126118 PMID:12486423
- Al-Khatib, S. M., Granger, C. B., Huang, Y., Lee, K. L., Califf, R. M., Simoons, M. L., Armstrong, P. W., Van de Werf, F., White, H. D., Simes, R. J., Moliterno, D. J., Topol, E. J., et al. Sustained ventricular arrhythmias among patients with acute coronary syndromes with no st-segment elevation - incidence, predictors, and outcomes Circulation 2002 106:309-312 DOI:10.1161/01.cir.0000022692.49934.e3 PMID:12119245
- Al-Khatib, S. M., Pieper, K. S., Lee, K. L., Mahaffey, K. W., Hochman, J. S., Pepine, C. J., Kopecky, S. L., Akkerhuis, M., Stepinska, J., Simoons, M. L., Topol, E. J., Califf, R. M., et al. Atrial fibrillation and mortality among patients with acute coronary syndromes without st-segment elevation: Results from the pursuit trial American Journal of Cardiology 2001 88:76-79 DOI:10.1016/s0002-9149(01)01593-4
- Lauer, M. A., Houghtaling, P. L., Peterson, J. G., Granger, C. B., Bhatt, D. L., Sapp, S. K., Simoons, M. L., Harrington, R. A., Topol, E. J., Lincoff, A. M. Attenuation of rebound ischemia after discontinuation of heparin therapy by glycoprotein iib/iiia inhibition with eptifibatide in patients with acute coronary syndromes - observations from the platelet iib/iiia in unstable angina: Receptor suppression using integrilin therapy (pursuit) trial Circulation 2001 104:2772-2777 DOI:10.1161/hc4801.100358 PMID:11733393
- Newby, L. K., Ohman, E. M., Christenson, R. H., Moliterno, D. J., Harrington, R. A., White, H. D., Armstrong, P. W., Van de Werf, F., Pfisterer, M., Hasselblad, V., Califf, R. M., Topol, E. J., et al. Benefit of glycoprotein iib/iiia inhibition in patients with acute coronary syndromes and troponin t-positive status - the paragon-b troponin t substudy Circulation 2001 103:2891-2896 DOI:10.1161/‚Äã01.CIR.103.24.2891 PMID:11413076
- Mahaffey, K. W., Harrington, R. A., Akkerhuis, M., Kleiman, N. S., Berdan, L. G., Crenshaw, B. S., Tardiff, B. E., Granger, C. B., DeJong, I., Bhapkar, M., Widimsky, P., Corbalon, R., et al. Disagreements between central clinical events committee and site investigator assessments of myocardial infarction endpoints in an international clinical trial: Review of the pursuit study Current Controlled Trials in Cardiovascular Medicine 2001 2:187-194 DOI:10.1186/cvm-2-4-187 PMID:11806794 PMCID:PMC57750
- Aronow, H. D., Topol, E. J., Roe, M. T., Houghtaling, P. L., Wolski, K. E., Lincoff, A. M., Harrington, R. A., Califf, R. M., Ohman, E. M., Kleiman, N. S., Keltai, M., Wilcox, R. G., et al. Effect of lipid-lowering therapy on early mortality after acute coronary syndromes: An observational study Lancet 2001 357:1063-1068 DOI:10.1016/s0140-6736(00)04257-4 PMID:11297956
- Peterson, J. G., Topol, E. J., Roe, M. T., Sapp, S. K., Lincoff, A. M., Deckers, J. W., Blackstone, E. H., Harrington, R. A., Califf, R. M., Lauer, M. S., Investigators, Pursuit Prognostic importance of concomitant heparin with eptifibatide in acute coronary syndromes American Journal of Cardiology 2001 87:532-536 DOI:10.1016/s0002-9149(00)01426-0 PMID:11230834
- Kaul, P., Fu, Y. L., Chang, W. C., Harrington, R. A., Wagner, G. S., Goodman, S. G., Granger, C. B., Moliterno, D. J., Van de Werf, F., Califf, R. N., Topol, E. J., Armstrong, P. W., et al. Prognostic value of st segment depression in acute coronary syndromes: Insights from paragon-a applied to gusto-iib Journal of the American College of Cardiology 2001 38:64-71 DOI:10.1016/s0735-1097(01)01307-9 PMID:11451297
- Mahaffey, K. W., Harrington, R. A., Akkerhuis, M., Kleiman, N. S., Berdan, L. G., Crenshaw, B. S., Tardiff, B. E., Granger, C. B., DeJong, I., Bhapkar, M., Widimsky, P., Corbalon, R., et al. Systematic adjudication of myocardial infarction end-points in an international clinical trial Current Controlled Trials in Cardiovascular Medicine 2001 2:180-186 DOI:10.1186/cvm-2-4-180 PMID:11806793 PMCID:PMC57749
- Greenbaum, A. B., Harrington, R. A., Hudson, M. P., MacAulay, C. M., Wilcox, R. G., Simoons, M. L., Berdan, L. G., Guerci, A., Cokkinos, D. V., Kitt, M. M., Lincoff, A. M., Topol, E. J., et al. Therapeutic value of eptifibatide at community hospitals transferring patients to tertiary referral centers early after admission for acute coronary syndromes Journal of the American College of Cardiology 2001 37:492-498 DOI:10.1016/s0735-1097(00)01143-8 PMID:11216968
- Cohen, M. G., Pacchiana, C. M., Corbalan, R., Perez, J. E. I., Ponte, C. I., Oropeza, E. S., Diaz, R., Paolasso, E., Izasa, D., Rodas, M. A., Urrutia, C. E., Harrington, R. A., et al. Variation in patient management and outcomes for acute coronary syndromes in latin america and north america: Results from the platelet iib/iiia in unstable angina: Receptor suppression using integrilin therapy (pursuit) trial American Heart Journal 2001 141:391-401 DOI:10.1067/mhj.2001.113216 PMID:11231436
- Hasdai, D., Holmes, D. R., Criger, D. A., Topol, E. J., Califf, R. M., Harrington, R. A., Pursuit Trial ,Investigators Age and outcome after acute coronary syndromes without persistent st-segment elevation American Heart Journal 2000 139:858-866 DOI:10.1016/s0002-8703(00)90018-8 PMID:10783220
- Alexander, J. H., Sparapani, R. A., Mahaffey, K. W., Deckers, J. W., Newby, L. K., Ohman, E. M., Corbalan, R., Chierchia, S. L., Boland, J. B., Simoons, M. L., Califf, R. M., Topol, E. J., et al. Association between minor elevations of creatine kinase-mb level and mortality in patients with acute coronary syndromes without st-segment elevation JAMA-Journal of the American Medical Association 2000 283:347-353 DOI:10.1001/jama.283.3.347 PMID:10647797
- Hasdai, D., Holmes, D. R., Criger, D. A., Topol, E. J., Califf, R. M., Wilcox, R. G., Paolasso, E., Simoons, M., Deckers, J., Harrington, R. A., investigators, Pursuit trial Cigarette smoking status and outcome among patients with acute coronary syndromes without persistent st-segment elevation: Effect of inhibition of platelet glycoprotein iib/iiia with eptifibatide American Heart Journal 2000 139:454-460 DOI:10.1067/mhj.2000.103847 PMID:10689260
- Roe, M. T., Harrington, R. A., Prosper, D. M., Pieper, K. S., Bhatt, D. L., Lincoff, A. M., Simoons, M. L., Akkerhuis, M., Ohman, E. M., Kitt, M. M., Vahanian, A., Ruzyllo, W., et al. Clinical and therapeutic profile of patients presenting with acute coronary syndromes who do not have significant coronary artery disease Circulation 2000 102:1101-1106 PMID:10973837
- Topol, C. E., Califf, R. M., Simes, R. J., Van de Werf, F., Diaz, R., Paolasso, E., Aylward, P. E., Keech, A., Klein, W., Piegas, L., Tomov, I., Armstrong, P. W., et al. Comparison of sibrafiban with aspirin for prevention of cardiovascular events after acute coronary syndromes: A randomised trial Lancet 2000 355:337-345 PMID:10665552
- Mark, D. B., Harrington, R. A., Lincoff, A. M., Califf, R. M., Nelson, C. L., Tsiatis, A. A., Buell, H., Mahaffey, K. W., Davidson-Ray, L., Topol, E. J. Cost-effectiveness of platelet glycoprotein IIb/IIIa inhibition with eptifibatide in patients with non-ST-elevation acute coronary syndromes Circulation 2000 101:366-371 PMID:10653826
- Harrington, R. A., Armstrong, P. W., Graffagnino, C., Van de Werf, F., Kereiakes, D. J., Sigmon, K. N., Card, T., Joseph, D. M., Samuels, R., Granett, J., Chan, R., Califf, R. M., et al. Dose-finding, safety, and tolerability study of an oral platelet glycoprotein IIb/IIIa inhibitor, lotrafiban, in patients with coronary or cerebral atherosclerotic disease Circulation 2000 102:728-735 PMID:10942739
- Kleiman, N. S., Lincoff, A. M., Flaker, G. C., Pieper, K. S., Wilcox, R. G., Berdan, L. G., Lorenz, T. J., Cokkinos, D. V., Simoons, M. L., Boersma, E., Topol, E. J., Califf, R. M., et al. Early percutaneous coronary intervention, platelet inhibition with eptifibatide, and clinical outcomes in patients with acute coronary syndromes Circulation 2000 101:751-757 PMID:10683348
- Marso, S. P., Bhatt, D. L., Roe, M. T., Houghtaling, P. L., Labinaz, M., Kleiman, N. S., Dyke, C., Simmoons, M. L., Califf, R. M., Harrington, R. A., Topol, E. J., Investigators, Pursuit Enhanced efficacy of eptifibatide administration in patients with acute coronary syndrome requiring in-hospital coronary artery bypass grafting Circulation 2000 102:2952-2958 PMID:11113045
- Akkerhuis, K. M., Deckers, J. W., Boersma, E., Harrington, R. A., Stepinska, J., Mahaffey, K. W., Wilcox, R. G., Lincoff, A. M., Keltai, M., Topol, E. J., Califf, R. M., Simoons, M. L., et al. Geographic variability in outcomes within an international trial of glycoprotein iib/iiia inhibition in patients with acute coronary syndromes - results from pursuit European Heart Journal 2000 21:371-381 DOI:10.1053/euhj.1999.1743 PMID:10666351
- Lincoff, A. M., Harrington, R. A., Califf, R. M., Hochman, J. S., Guerci, A. D., Ohman, E. M., Pepine, C. J., Kopecky, S. L., Kleiman, N. S., Pacchiana, C. M., Berdan, L. G., Kitt, M. M., et al. Management of patients with acute coronary syndromes in the united states by platelet glycoprotein iib/iiia inhibition - insights from the platelet glycoprotein iib/iiia in unstable angina: Receptor suppression using integrilin therapy (pursuit) trial Circulation 2000 102:1093-1100 PMID:10973836
- Sane, D. C., Damaraju, L. V., Topol, E. J., Cabot, C. F., Mascelli, M. A., Harrington, R. A., Simoons, M. L., Califf, R. M. Occurrence and clinical significance of pseudothrombocytopenia during abciximab therapy Journal of the American College of Cardiology 2000 36:75-83 DOI:10.1016/s0735-1097(00)00688-4 PMID:10898416
- Hasdai, D., Harrington, R. A., Hochman, J. S., Califf, R. M., Battler, A., Box, J. W., Simoons, M. L., Deckers, J., Topol, E. J., Holmes, D. R. Platelet glycoprotein iib/iiia blockade and outcome of cardiogenic shock complicating acute coronary syndromes without persistent st-segment elevation Journal of the American College of Cardiology 2000 36:685-692 DOI:10.1016/s0735-1097(00)00814-7 PMID:10987585
- Boersma, E., Pieper, K. S., Steyerberg, E. W., Wilcox, R. G., Chang, W. C., Lee, K. L., Akkerhuis, K. M., Harrington, R. A., Deckers, J. W., Armstrong, P. W., Lincoff, A. M., Califf, R. M., et al. Predictors of outcome in patients with acute coronary syndromes without persistent ST-segment elevation results from an international trial of 9461 patients Circulation 2000 101:2557-2567 PMID:10840005
- Braunwald, E., Califf, R. M., Cannon, C. P., Fox, K. A. A., Fuster, V., Gibler, W. B., Harrington, R. A., King, S. B., Kleiman, N. S., Theroux, P., Topol, E. J., Van de Werf, F., et al. Redefining medical treatment in the management of unstable angina American Journal of Medicine 2000 108:41-53 DOI:10.1016/s0002-9343(99)00416-7 PMID:11059440
- Tardiff, B. E., Califf, R. M., Tcheng, J. E., Lincoff, A. M., Sigmon, K. N., Harrington, R. A., Mahaffey, K. W., Ohman, E. M., Teirstein, P. S., Blankenship, J. C., Kitt, M. M., Topol, E. J., et al. Clinical outcomes after detection of elevated cardiac enzymes in patients undergoing percutaneous intervention Journal of the American College of Cardiology 1999 33:88-96 DOI:10.1016/s0735-1097(98)00551-8 PMID:9935014
- McClure, M. W., Berkowitz, S. D., Sparapani, R., Tuttle, R., Kleiman, N. S., Berdan, L. G., Lincoff, A. M., Deckers, J., Diaz, R., Karsch, K. R., Gretler, D., Kitt, M., et al. Clinical significance of thrombocytopenia during a non-st-elevation acute coronary syndrome - the platelet glycoprotein iib iiia in unstable angina: Receptor suppression using integrilin therapy (pursuit) trial experience Circulation 1999 99:2892-2900 PMID:10359733
- Harrington, R. A., Califf, R. M., Holmes, D. R., Pieper, K. S., Lincoff, A. M., Berdan, L. G., Thompson, T. D., Topol, E. J., Investigators, Caveat- I. Is all unstable angina the same? Insights from the coronary angioplasty versus excisional atherectamy trial (caveat-i) American Heart Journal 1999 137:227-233 DOI:10.1053/hj.1999.v137.90600 PMID:9924155
- Alexander, J. H., Harrington, R. A., Tuttle, R. H., Berdan, L. G., Lincoff, A. M., Deckers, J. W., Simoons, M. L., Guerci, A., Hochman, J. S., Wilcox, R. G., Kitt, M. M., Eisenberg, P. R., et al. Prior aspirin use predicts worse outcomes in patients with non-st-elevation acute coronary syndromes American Journal of Cardiology 1999 83:1147-1151 DOI:10.1016/s0002-9149(99)00049-1 PMID:10215274
- Mahaffey, K. W., Harrington, R. A., Simoons, M. L., Granger, C. B., Graffagnino, C., Alberts, M. J., Laskowitz, D. T., Miller, J. M., Sloan, M. A., Berdan, L. G., MacAulay, C. M., Lincoff, A. M., et al. Stroke in patients with acute coronary syndromes - incidence and outcomes in the platelet glycoprotein iib/iiia in unstable angina: Receptor suppression using integrilin therapy (pursuit) trial Circulation 1999 99:2371-2377 PMID:10318656
- Kong, D. F., Califf, R. M., Miller, D. P., Moliterno, D. J., White, H. D., Harrington, R. A., Tcheng, J. E., Lincoff, A. M., Hasselblad, V., Topol, E. J. Clinical outcomes of therapeutic agents that block the platelet glycoprotein iib/iiia integrin in ischemic heart disease Circulation 1998 98:2829-2835 PMID:9860783
- Califf, R. M., Abdelmeguid, A. E., Kuntz, R. E., Popma, J. J., Davidson, C. J., Cohen, E. A., Kleiman, N. S., Mahaffey, K. W., Topol, E. J., Pepine, C. J., Lipicky, R. J., Granger, C. B., et al. Myonecrosis after revascularization procedures Journal of the American College of Cardiology 1998 31:241-251 DOI:10.1016/s0735-1097(97)00506-8 PMID:9462562
- Berkowitz, S. D., Sane, D. C., Sigmon, K. N., Shavender, J. H., Harrington, R. A., Tcheng, J. E., Topol, E. J., Califf, R. M., Eval c, E. Prev Isch Compl Epic Stud Grp Occurrence and clinical significance of thrombocytopenia in a population undergoing high-risk percutaneous coronary revascularization Journal of the American College of Cardiology 1998 32:311-319 DOI:10.1016/s0735-1097(98)00252-6 PMID:9708455
- Anderson, R. D., Ohman, E. M., Holmes, D. R., Harrington, R. A., Barsness, G. W., Wildermann, N. M., Phillips, H. R., Topol, E. J., Califf, R. M. Prognostic value of congestive heart failure history in patients undergoing percutaneous coronary interventions Journal of the American College of Cardiology 1998 32:936-941 DOI:10.1016/s0735-1097(98)00339-8 PMID:9768714
- Lincoff, A. M., Califf, R. M., Anderson, K. M., Weisman, H. F., Aguirre, F. V., Kleiman, N. S., Harrington, R. A., Topol, E. J. Evidence for prevention of death and myocardial infarction with platelet membrane glycoprotein iib/iiia receptor blockade by abciximab (c7e3 fab) among patients with unstable angina undergoing percutaneous coronary revascularization Journal of the American College of Cardiology 1997 30:149-156 PMID:9207636
- Tcheng, J. E., Lincoff, A. M., Sigmon, K. N., Lee, K. L., Kitt, M. M., Califf, R. M., Topol, E. J., Juran, N., Worley, S., Tuzi, J., Hollywood, L., Kleiman, N. S., et al. Randomised placebo-controlled trial of effect of eptifibatide on complications of percutaneous coronary intervention: IMPACT II Lancet 1997 349:1422-1428 PMID:9164315
- Rao, A. K., Sun, L., Chesebro, J. H., Fuster, V., Harrington, R. A., Schwartz, D., Gallo, P., Matos, D., Topol, E. J. Distinct effects of recombinant desulfatohirudin (revasc) and heparin on plasma levels of fibrinopeptide a and prothrombin fragment f1.2 in unstable angina - a multicenter trial Circulation 1996 94:2389-2395 PMID:8921778
- Schulman, S. P., GoldschmidtClermont, P. J., Topol, E. J., Califf, R. M., Navetta, F. I., Willerson, J. T., Chandra, N. C., Guerci, A. D., Ferguson, J. J., Harrington, R. A., Lincoff, A. M., Yakubov, S. J., et al. Effects of integrelin, a platelet glycoprotein iib/iiia receptor antagonist, in unstable angina - a randomized multicenter trial Circulation 1996 94:2083-2089 PMID:8901655
- Harrington, R. A., Lincoff, A. M., Califf, R. M., Holmes, D. R., Berdan, L. G., Ohanesian, M. A., Keeler, G. P., Garratt, K. N., Ohman, E. M., Mark, D. B., Jacobs, A. K., Topol, E. J. Characteristics and consequences of myocardial-infarction after percutaneous coronary intervention - insights from the coronary angioplasty versus excisional atherectomy trial (caveat) Journal of the American College of Cardiology 1995 25:1693-1699 DOI:10.1016/0735-1097(95)00091-h PMID:7759725
- Harrington, R. A., Kleiman, N. S., Kottkemarchant, K., Lincoff, A. M., Tcheng, J. E., Sigmon, K. N., Joseph, D., Rios, G., Trainor, K., Rose, D., Greenberg, C. S., Kitt, M. M., et al. Immediate and reversible platelet inhibition after intravenous administration of a peptide glycoprotein iib/iiia inhibitor during percutaneous coronary intervention American Journal of Cardiology 1995 76:1222-1227 DOI:10.1016/s0002-9149(99)80345-2 PMID:7503000
- Tcheng, J. E., Harrington, R. A., Kottkemarchant, K., Kleiman, N. S., Ellis, S. G., Kereiakes, D. J., Mick, M. J., Navetta, F. I., Smith, J. E., Worley, S. J., Miller, J. A., Joseph, D. M., et al. Multicenter, randomized, double-blind, placebo-controlled trial of the platelet integrin glycoprotein iib/iiia blocker integrelin in elective coronary intervention Circulation 1995 91:2151-2157 PMID:7697843
- Harrington, R. A., Sane, D. C., Califf, R. M., Sigmon, K. N., Abbottsmith, C. W., Candela, R. J., Lee, K. L., Topol, E. J. Clinical importance of thrombocytopenia occurring in the hospital phase after administration of thrombolytic therapy for acute myocardial-infarction Journal of the American College of Cardiology 1994 23:891-898 PMID:8106694
- Topol, E. J., Fuster, V., Harrington, R. A., Califf, R. M., Kleiman, N. S., Kereiakes, D. J., Cohen, M., Chapekis, A., Gold, H. K., Tannenbaum, M. A., Rao, A. K., Debowey, D., et al. Recombinant hirudin for unstable angina-pectoris - a multicenter, randomized angiographic trial Circulation 1994 89:1557-1566 PMID:8149521