recent publications

• academic article

  • Dreier, B., Fuller, R. P., Segal, D. J., Lund, C. V., Blancafort, P., Huber, A., Koksch, B., Barbas, C. F. Development of zinc finger domains for recognition of the 5'-CNN-3' family DNA sequences and their use in the construction of artificial transcription factors Journal of Biological Chemistry  2005 280:35588-35597  DOI:10.1074/jbc.M506654200  PMID:16107335
  • Segal, D. J., Beerli, R. R., Blancafort, P., Dreier, B., Effertz, K., Huber, A., Koksch, B., Lund, C. V., Magnenat, L., Valente, D., Barbas, C. F. Evaluation of a modular strategy for the construction of novel polydactyl zinc finger DNA-binding proteins Biochemistry  2003 42:2137-2148  DOI:10.1021/bi026806o  PMID:12590603
  • Dreier, B., Beerli, R. R., Segal, D. J., Flippin, J. D., Barbas, C. F. Development of zinc finger domains for recognition of the 5 '-ann-3 ' family of DNA sequences and their use in the construction of artificial transcription factors Journal of Biological Chemistry  2001 276:29466-29478  DOI:10.1074/jbc.M102604200  PMID:11340073
  • Dreier, B., Segal, D. J., Barbas, C. F. Insights into the molecular recognition of the 5 '-gnn-3 ' family of DNA sequences by zinc finger domains Journal of Molecular Biology  2000 303:489-502  DOI:10.1006/jmbi.2000.4133  PMID:11054286
  • Beerli, R. R., Schopfer, U., Dreier, B., Barbas, C. F. Chemically regulated zinc finger transcription factors Journal of Biological Chemistry  2000 275:32617-32627  DOI:10.1074/jbc.M005108200  PMID:10924515
  • Beerli, R. R., Dreier, B., Barbas, C. F. Positive and negative regulation of endogenous genes by designed transcription factors Proceedings of the National Academy of Sciences of the United States of America  2000 97:1495-1500  DOI:10.1073/pnas.040552697  PMID:10660690  PMCID:PMC26462
  • Segal, D. J., Dreier, B., Beerli, R. R., Barbas, C. F. Toward controlling gene expression at will: Selection and design of zinc finger domains recognizing each of the 5 '-gnn-3 ' DNA target sequences Proceedings of the National Academy of Sciences of the United States of America  1999 96:2758-2763  DOI:10.1073/pnas.96.6.2758  PMID:10077584
  • Beerli, R. R., Segal, D. J., Dreier, B., Barbas, C. F. Toward controlling gene expression at will: Specific regulation of the erbb-2/her-2 promoter by using polydactyl zinc finger proteins constructed from modular building blocks Proceedings of the National Academy of Sciences of the United States of America  1998 95:14628-14633  DOI:10.1073/pnas.95.25.14628  PMID:9843940