recent publications
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academic article
- Dreier, B., Fuller, R. P., Segal, D. J., Lund, C. V., Blancafort, P., Huber, A., Koksch, B., Barbas, C. F. Development of zinc finger domains for recognition of the 5'-CNN-3' family DNA sequences and their use in the construction of artificial transcription factors Journal of Biological Chemistry 2005 280:35588-35597 DOI:10.1074/jbc.M506654200 PMID:16107335
- Segal, D. J., Beerli, R. R., Blancafort, P., Dreier, B., Effertz, K., Huber, A., Koksch, B., Lund, C. V., Magnenat, L., Valente, D., Barbas, C. F. Evaluation of a modular strategy for the construction of novel polydactyl zinc finger DNA-binding proteins Biochemistry 2003 42:2137-2148 DOI:10.1021/bi026806o PMID:12590603
- Dreier, B., Beerli, R. R., Segal, D. J., Flippin, J. D., Barbas, C. F. Development of zinc finger domains for recognition of the 5 '-ann-3 ' family of DNA sequences and their use in the construction of artificial transcription factors Journal of Biological Chemistry 2001 276:29466-29478 DOI:10.1074/jbc.M102604200 PMID:11340073
- Dreier, B., Segal, D. J., Barbas, C. F. Insights into the molecular recognition of the 5 '-gnn-3 ' family of DNA sequences by zinc finger domains Journal of Molecular Biology 2000 303:489-502 DOI:10.1006/jmbi.2000.4133 PMID:11054286
- Beerli, R. R., Schopfer, U., Dreier, B., Barbas, C. F. Chemically regulated zinc finger transcription factors Journal of Biological Chemistry 2000 275:32617-32627 DOI:10.1074/jbc.M005108200 PMID:10924515
- Beerli, R. R., Dreier, B., Barbas, C. F. Positive and negative regulation of endogenous genes by designed transcription factors Proceedings of the National Academy of Sciences of the United States of America 2000 97:1495-1500 DOI:10.1073/pnas.040552697 PMID:10660690 PMCID:PMC26462
- Segal, D. J., Dreier, B., Beerli, R. R., Barbas, C. F. Toward controlling gene expression at will: Selection and design of zinc finger domains recognizing each of the 5 '-gnn-3 ' DNA target sequences Proceedings of the National Academy of Sciences of the United States of America 1999 96:2758-2763 DOI:10.1073/pnas.96.6.2758 PMID:10077584
- Beerli, R. R., Segal, D. J., Dreier, B., Barbas, C. F. Toward controlling gene expression at will: Specific regulation of the erbb-2/her-2 promoter by using polydactyl zinc finger proteins constructed from modular building blocks Proceedings of the National Academy of Sciences of the United States of America 1998 95:14628-14633 DOI:10.1073/pnas.95.25.14628 PMID:9843940