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Cyp2c9*3 and *13 alleles significantly affect the pharmacokinetics of irbesartan in healthy korean subjects

Academic Article
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  • Research
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Overview

authors

  • Choi, C. I.
  • Kim, M. J.
  • Chung, E. K.
  • Lee, H. I.
  • Jang, Choon-Gon
  • Bae, J. W.
  • Lee, S. Y.

publication date

  • February 2012

journal

  • European Journal of Clinical Pharmacology  Journal

subject areas

  • Alleles
  • Angiotensin II Type 1 Receptor Blockers
  • Antihypertensive Agents
  • Area Under Curve
  • Aryl Hydrocarbon Hydroxylases
  • Asian Continental Ancestry Group
  • Biphenyl Compounds
  • Cytochrome P-450 CYP2C9
  • Genotype
  • Half-Life
  • Humans
  • Polymorphism, Genetic
  • Tetrazoles
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Research

keywords

  • CYP2C9
  • Genetic polymorphism
  • Irbesartan
  • Pharmacokinetics
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Identity

International Standard Serial Number (ISSN)

  • 0031-6970

Digital Object Identifier (DOI)

  • 10.1007/s00228-011-1098-0

PubMed ID

  • 21842338
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Additional Document Info

start page

  • 149

end page

  • 154

volume

  • 68

issue

  • 2

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