recent publications

• academic article

  • Shoemaker, W. J., Balentine, L. T., Siggins, G. R., Hoffer, B. J., Henriksen, S. J., Bloom, F. E. Characteristics of release of adenosine 3'-5' - monophosphate from micropipets by microiontophoresis Journal of Cyclic Nucleotide Research  1975 1:97-106  PMID:4474
  • Siggins, G. R., Hoffer, B. J., Ungerstedt, U. Electrophysiological evidence for involvement of cyclic adenosine monophosphate in dopamine responses of caudate neurons Life Sciences  1974 15:779-792  DOI:10.1016/0024-3205(74)90516-5  PMID:4378085
  • Bloom, F. E., Siggins, G. R., Hoffer, B. J. Interpreting failures to confirm depression of cerebellar purkinje-cells by cyclic-amp Science  1974 185:627-629  DOI:10.1126/science.185.4151.627  PMID:4366788
  • Hoffer, B. J., Siggins, G. R., Oliver, A. P., Bloom, F. E. Activation of pathway from locus coeruleus to rat cerebellar purkinje neurons - pharmacological evidence of noradrenergic central inhibition Journal of Pharmacology and Experimental Therapeutics  1973 184:553-569  PMID:4347049
  • Nelson, C. N., Hoffer, B. J., Chu, N. S., Bloom, F. E. Cytochemical and pharmacological studies on polysensory neurons in primate frontal cortex Brain Research  1973 62:115-133  DOI:10.1016/0006-8993(73)90623-9  PMID:4148775
  • Siggins, G. R., Battenberg, E. F., Hoffer, B. J., Bloom, F. E., Steiner, A. L. Noradrenergic stimulation of cyclic adenosine monophosphate in rat purkinje neurons: An immunocytochemical study Science  1973 179:585-588  DOI:10.1126/science.179.4073.585  PMID:4346826
  • Bloom, F. E., Hoffer, B. J., Battenberg, E. R., Siggins, G. R., Steiner, A. L., Parker, C. W., Wedner, H. J. Adenosine 3',5'-monophosphate is localized in cerebellar neurons: Immunofluorescence evidence Science  1972 177:436-438  DOI:10.1126/science.177.4047.436  PMID:4339615
  • Hoffer, B. J., Siggins, G. R., Oliver, A. P., Bloom, F. E. Cyclic AMP-mediated adrenergic synapses to cerebellar Purkinje cells Advances in Cyclic Nucleotide Research  1972 1:411-423  PMID:4353180
  • Bloom, F. E., Barker, J. L., Hoffer, B. J., Siggins, G. R., Nicoll, R. A. Effects of serotonin on central neurons: Microiontophoretic administration Federation Proceedings  1972 31:97-106  PMID:4333253
  • Bloom, F. E., Hoffer, B. J., Siggins, G. R. Norepinephrine mediated cerebellar synapses: A model system for neuropsychopharmacology Biological Psychiatry  1972 4:157-177  PMID:4337435
  • Siggins, G. R., Hoffer, B. J., Oliver, A. P., Bloom, F. E. Activation of a central noradrenergic projection to cerebellum Nature  1971 233:481-483  DOI:10.1038/233481a0  PMID:4939543
  • Godfraind, J. M., Pumain, R., Siggins, G. R., Hoffer, B. J., Bloom, F. E. Cyclic adenosine monophosphate and norepinephrine: Effect on purkinje cells in rat cerebellar cortex Science  1971 174:1257-1259  PMID:4332286
  • Siggins, G. R., Oliver, A. P., Hoffer, B. J., Bloom, F. E. Cyclic adenosine monophosphate and norepinephrine: Effects on transmembrane properties of cerebellar purkinje cells Science  1971 171:192-194  DOI:10.1126/science.171.3967.192  PMID:4322158
  • Hoffer, B. J., Siggins, G. R., Oliver, A. P., Bloom, F. E. Cyclic amp mediation of norepinephrine inhibition in rat cerebellar cortex: A unique class of synaptic responses Annals of the New York Academy of Sciences  1971 185:531-549  PMID:4330518
  • Woodward, D. J., Hoffer, B. J., Siggins, G. R., Oliver, A. P. Inhibition of purkinje cells in the frog cerebellum. Ii. Evidence for gaba as the inhibitory transmitter Brain Research  1971 33:91-100  DOI:10.1016/0006-8993(71)90308-8  PMID:4330216
  • Hoffer, B. J., Neff, N. H., Siggins, G. R. Microiontophoretic release of norepinephrine from micropipettes Neuropharmacology  1971 10:175-180  DOI:10.1016/0028-3908(71)90038-4  PMID:5093958
  • Hoffer, B. J., Siggins, G. R., Woodward, D. J., Bloom, F. E. Spontaneous discharge of purkinje neurons after destruction of catecholamine-containing afferents by 6-hydroxydopamine Brain Research  1971 30:425-430  DOI:10.1016/0006-8993(71)90095-3  PMID:4329214
  • Bloom, F. E., Hoffer, B. J., Siggins, G. R. Studies on norepinephrine-containing afferents to purkinje cells of art cerebellum. I. Localization of the fibers and their synapses Brain Research  1971 25:501-521  DOI:10.1016/0006-8993(71)90457-4  PMID:5544323
  • Siggins, G. R., Hoffer, B. J., Bloom, F. E. Studies on norepinephrine-containing afferents to purkinje cells of rat cerebellum. 3. Evidence for mediation of norepinephrine effects by cyclic 3',5'-adenosine monophosphate Brain Research  1971 25:535-553  DOI:10.1016/0006-8993(71)90459-8  PMID:4322679
  • Hoffer, B. J., Siggins, G. R., Bloom, F. E. Studies on norepinephrine-containing afferents to purkinje cells of rat cerebellum. Ii. Sensitivity of purkinje cells to norepinephrine and related substances administered by microiontophoresis Brain Research  1971 25:523-534  DOI:10.1016/0006-8993(71)90458-6  PMID:4395919
  • Woodward, D. J., Hoffer, B. J., Siggins, G. R., Bloom, F. E. The ontogenetic development of synaptic junctions, synaptic activation and responsiveness to neurotransmitter substances in rat cerebellar purkinje cells Brain Research  1971 34:73-97  DOI:10.1016/0006-8993(71)90352-0  PMID:4330971
  • Siggins, G. R., Hoffer, B. J., Bloom, F. E. Cyclic adenosine monophosphate: Possible mediator for norepinephrine effects on cerebellar purkinje cells Science  1969 165:1018-1020  DOI:10.1126/science.165.3897.1018  PMID:4308638
  • Hoffer, B. J., Siggins, G. R., Bloom, F. E. Prostaglandins e1 and e2 antagonize norepinephrine effects on cerebellar purkinje cells: Microelectrophoretic study Science  1969 166:1418-1420  DOI:10.1126/science.166.3911.1418  PMID:5350346