recent publications
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academic article
- Shoemaker, W. J., Balentine, L. T., Siggins, G. R., Hoffer, B. J., Henriksen, S. J., Bloom, F. E. Characteristics of release of adenosine 3'-5' - monophosphate from micropipets by microiontophoresis Journal of Cyclic Nucleotide Research 1975 1:97-106 PMID:4474
- Siggins, G. R., Hoffer, B. J., Ungerstedt, U. Electrophysiological evidence for involvement of cyclic adenosine monophosphate in dopamine responses of caudate neurons Life Sciences 1974 15:779-792 DOI:10.1016/0024-3205(74)90516-5 PMID:4378085
- Bloom, F. E., Siggins, G. R., Hoffer, B. J. Interpreting failures to confirm depression of cerebellar purkinje-cells by cyclic-amp Science 1974 185:627-629 DOI:10.1126/science.185.4151.627 PMID:4366788
- Hoffer, B. J., Siggins, G. R., Oliver, A. P., Bloom, F. E. Activation of pathway from locus coeruleus to rat cerebellar purkinje neurons - pharmacological evidence of noradrenergic central inhibition Journal of Pharmacology and Experimental Therapeutics 1973 184:553-569 PMID:4347049
- Nelson, C. N., Hoffer, B. J., Chu, N. S., Bloom, F. E. Cytochemical and pharmacological studies on polysensory neurons in primate frontal cortex Brain Research 1973 62:115-133 DOI:10.1016/0006-8993(73)90623-9 PMID:4148775
- Siggins, G. R., Battenberg, E. F., Hoffer, B. J., Bloom, F. E., Steiner, A. L. Noradrenergic stimulation of cyclic adenosine monophosphate in rat purkinje neurons: An immunocytochemical study Science 1973 179:585-588 DOI:10.1126/science.179.4073.585 PMID:4346826
- Bloom, F. E., Hoffer, B. J., Battenberg, E. R., Siggins, G. R., Steiner, A. L., Parker, C. W., Wedner, H. J. Adenosine 3',5'-monophosphate is localized in cerebellar neurons: Immunofluorescence evidence Science 1972 177:436-438 DOI:10.1126/science.177.4047.436 PMID:4339615
- Hoffer, B. J., Siggins, G. R., Oliver, A. P., Bloom, F. E. Cyclic AMP-mediated adrenergic synapses to cerebellar Purkinje cells Advances in Cyclic Nucleotide Research 1972 1:411-423 PMID:4353180
- Bloom, F. E., Barker, J. L., Hoffer, B. J., Siggins, G. R., Nicoll, R. A. Effects of serotonin on central neurons: Microiontophoretic administration Federation Proceedings 1972 31:97-106 PMID:4333253
- Bloom, F. E., Hoffer, B. J., Siggins, G. R. Norepinephrine mediated cerebellar synapses: A model system for neuropsychopharmacology Biological Psychiatry 1972 4:157-177 PMID:4337435
- Siggins, G. R., Hoffer, B. J., Oliver, A. P., Bloom, F. E. Activation of a central noradrenergic projection to cerebellum Nature 1971 233:481-483 DOI:10.1038/233481a0 PMID:4939543
- Godfraind, J. M., Pumain, R., Siggins, G. R., Hoffer, B. J., Bloom, F. E. Cyclic adenosine monophosphate and norepinephrine: Effect on purkinje cells in rat cerebellar cortex Science 1971 174:1257-1259 PMID:4332286
- Siggins, G. R., Oliver, A. P., Hoffer, B. J., Bloom, F. E. Cyclic adenosine monophosphate and norepinephrine: Effects on transmembrane properties of cerebellar purkinje cells Science 1971 171:192-194 DOI:10.1126/science.171.3967.192 PMID:4322158
- Hoffer, B. J., Siggins, G. R., Oliver, A. P., Bloom, F. E. Cyclic amp mediation of norepinephrine inhibition in rat cerebellar cortex: A unique class of synaptic responses Annals of the New York Academy of Sciences 1971 185:531-549 PMID:4330518
- Woodward, D. J., Hoffer, B. J., Siggins, G. R., Oliver, A. P. Inhibition of purkinje cells in the frog cerebellum. Ii. Evidence for gaba as the inhibitory transmitter Brain Research 1971 33:91-100 DOI:10.1016/0006-8993(71)90308-8 PMID:4330216
- Hoffer, B. J., Neff, N. H., Siggins, G. R. Microiontophoretic release of norepinephrine from micropipettes Neuropharmacology 1971 10:175-180 DOI:10.1016/0028-3908(71)90038-4 PMID:5093958
- Hoffer, B. J., Siggins, G. R., Woodward, D. J., Bloom, F. E. Spontaneous discharge of purkinje neurons after destruction of catecholamine-containing afferents by 6-hydroxydopamine Brain Research 1971 30:425-430 DOI:10.1016/0006-8993(71)90095-3 PMID:4329214
- Bloom, F. E., Hoffer, B. J., Siggins, G. R. Studies on norepinephrine-containing afferents to purkinje cells of art cerebellum. I. Localization of the fibers and their synapses Brain Research 1971 25:501-521 DOI:10.1016/0006-8993(71)90457-4 PMID:5544323
- Siggins, G. R., Hoffer, B. J., Bloom, F. E. Studies on norepinephrine-containing afferents to purkinje cells of rat cerebellum. 3. Evidence for mediation of norepinephrine effects by cyclic 3',5'-adenosine monophosphate Brain Research 1971 25:535-553 DOI:10.1016/0006-8993(71)90459-8 PMID:4322679
- Hoffer, B. J., Siggins, G. R., Bloom, F. E. Studies on norepinephrine-containing afferents to purkinje cells of rat cerebellum. Ii. Sensitivity of purkinje cells to norepinephrine and related substances administered by microiontophoresis Brain Research 1971 25:523-534 DOI:10.1016/0006-8993(71)90458-6 PMID:4395919
- Woodward, D. J., Hoffer, B. J., Siggins, G. R., Bloom, F. E. The ontogenetic development of synaptic junctions, synaptic activation and responsiveness to neurotransmitter substances in rat cerebellar purkinje cells Brain Research 1971 34:73-97 DOI:10.1016/0006-8993(71)90352-0 PMID:4330971
- Siggins, G. R., Hoffer, B. J., Bloom, F. E. Cyclic adenosine monophosphate: Possible mediator for norepinephrine effects on cerebellar purkinje cells Science 1969 165:1018-1020 DOI:10.1126/science.165.3897.1018 PMID:4308638
- Hoffer, B. J., Siggins, G. R., Bloom, F. E. Prostaglandins e1 and e2 antagonize norepinephrine effects on cerebellar purkinje cells: Microelectrophoretic study Science 1969 166:1418-1420 DOI:10.1126/science.166.3911.1418 PMID:5350346