recent publications

• academic article

  • Huang, S. X., Feng, Z. Y., Wang, L. Y., Galm, U., Wendt-Pienkowski, E., Yang, D., Tao, M. F., Coughlin, J. M., Duan, Y. W., Shen, B. A designer bleomycin with significantly improved DNA cleavage activity Journal of the American Chemical Society  2012 134:13501-13509  DOI:10.1021/ja3056535  PMID:22831455  PMCID:PMC3422780
  • Zhao, L. X., Huang, S. X., Tang, S. K., Jiang, C. L., Duan, Y. W., Beutler, J. A., Henrich, C. J., McMahon, J. B., Schmid, T., Blees, J. S., Colburn, N. H., Rajski, S. R., et al. Actinopolysporins a-c and tubercidin as a pdcd4 stabilizer from the halophilic actinomycete actinopolyspora erythraea yim 90600 Journal of Natural Products  2011 74:1990-1995  DOI:10.1021/np200603g  PMID:21870828  PMCID:PMC3179765
  • Yu, Z. G., Zhao, L. X., Jiang, C. L., Duan, Y. W., Wong, L., Carver, K. C., Schuler, L. A., Shen, B. Bafilomycins produced by an endophytic actinomycete streptomyces sp yim56209 Journal of Antibiotics  2011 64:159-162  DOI:10.1038/ja.2010.147  PMID:21102599
  • Huang, S. X., Yu, Z. G., Robert, F., Zhao, L. X., Jiang, Y., Duan, Y. W., Pelletier, J., Shen, B. Cycloheximide and congeners as inhibitors of eukaryotic protein synthesis from endophytic actinomycetes streptomyces sps. Yim56132 and yim56141 Journal of Antibiotics  2011 64:163-166  DOI:10.1038/ja.2010.150  PMID:21139626
  • Huang, S. X., Powell, E., Rajski, S. R., Zhao, L. X., Jiang, C. L., Duan, Y. W., Xu, W., Shen, B. Discovery and total synthesis of a new estrogen receptor heterodimerizing actinopolymorphol a from actinopolymorpha rutilus Organic Letters  2010 12:3525-3527  DOI:10.1021/ol1013526  PMID:20593804  PMCID:PMC2913291
  • Zhang, N. N., Zhu, X. C., Yang, D., Cai, J., Tao, M. F., Wang, L. Y., Duan, Y. W., Shen, B., Xu, Z. N. Improved production of the tallysomycin h-1 in streptoalloteichus hindustanus sb8005 strain by fermentation optimization Applied Microbiology and Biotechnology  2010 86:1345-1353  DOI:10.1007/s00253-009-2406-9  PMID:20049429
  • Huang, S. X., Zhao, L. X., Tang, S. K., Jiang, C. L., Duan, Y. W., Shen, B. Erythronolides h and i, new erythromycin congeners from a new halophilic actinomycete actinopolyspora sp yim90600 Organic Letters  2009 11:1353-1356  DOI:10.1021/ol900143j  PMID:19228040  PMCID:PMC4123550