recent publications

• academic article

  • Gemmill, K. B., Diaz, S. A., Blanco-Canosa, J. B., Deschamps, J. R., Pons, T., Liu, H. W., Deniz, A., Melinger, J., Oh, E., Susumu, K., Stewart, M. H., Hastman Jr., D. A., et al. Examining the polyproline nanoscopic ruler in the context of quantum dots Chemistry of Materials  2015 27:6222-6237  DOI:10.1021/acs.chemmater.5b03181
  • Walters, R., Medintz, I. L., Delehanty, J. B., Stewart, M. H., Susumu, K., Huston, A. L., Dawson, P. E., Dawson, G. The role of negative charge in the delivery of quantum dots to neurons ASN Neuro  2015 7:pii  DOI:10.1177/1759091415592389  PMID:26243591  PMCID:PMC4550297
  • Scott, A. M., Algar, W. R., Stewart, M. H., Trammell, S. A., Blanco-Canosa, J. B., Dawson, P. E., Deschamps, J. R., Goswami, R., Oh, E., Huston, A. L., Medintz, I. L. Probing the quenching of quantum dot photoluminescence by peptide-labeled ruthenium(II) complexes Journal of Physical Chemistry C  2014 118:9239-9250  DOI:10.1021/jp501039w  PMID:24817922  PMCID:PMC4010286
  • Blanco-Canosa, J. B., Wu, M., Susumu, K., Petryayeva, E., Jennings, T. L., Dawson, P. E., Algar, W. R., Medintz, I. L. Recent progress in the bioconjugation of quantum dots Coordination Chemistry Reviews  2014 263:101-137  DOI:10.1016/j.ccr.2013.08.030
  • Stewart, M. H., Huston, A. L., Scott, A. M., Oh, E., Algar, W. R., Deschamps, J. R., Susumu, K., Jain, V., Prasuhn, D. E., Blanco-Canosa, J., Dawson, P. E., Medintz, I. L. Competition between Förster resonance energy transfer and electron transfer in stoichiometrically assembled semiconductor quantum dot-fullerene conjugates ACS Nano  2013 7:9489-9505  DOI:10.1021/nn403872x  PMID:24128175
  • Bradburne, C. E., Delehanty, J. B., Gemmill, K. B., Mei, B. C., Mattoussi, H., Susumu, K., Blanco-Canosa, J. B., Dawson, P. E., Medintz, I. L. Cytotoxicity of quantum dots used for in vitro cellular labeling: role of QD surface ligand, delivery modality, cell type, and direct comparison to organic fluorophores Bioconjugate Chemistry  2013 24:1570-1583  DOI:10.1021/bc4001917  PMID:23879393
  • Gemmill, K. B., Muttenthaler, M., Delehanty, J. B., Stewart, M. H., Susumu, K., Dawson, P. E., Medintz, I. L. Evaluation of diverse peptidyl motifs for cellular delivery of semiconductor quantum dots Analytical and Bioanalytical Chemistry  2013 405:6145-6154  DOI:10.1007/s00216-013-6982-2  PMID:23732866
  • Boeneman, K., Delehanty, J. B., Blanco-Canosa, J. B., Susumu, K., Stewart, M. H., Oh, E., Huston, A. L., Dawson, G., Ingale, S., Walters, R., Domowicz, M., Deschamps, J. R., et al. Selecting improved peptidyl motifs for cytosolic delivery of disparate protein and nanoparticle materials ACS Nano  2013 7:3778-3796  DOI:10.1021/nn400702r  PMID:23710591  PMCID:PMC3880025
  • Delehanty, J. B., Blanco-Canosa, J. B., Bradburne, C. E., Susumu, K., Stewart, M. H., Prasuhn, D. E., Dawson, P. E., Medintz, I. L. Site-specific cellular delivery of quantum dots with chemoselectively-assembled modular peptides Chemical Communications  2013 49:7878-7880  DOI:10.1039/c3cc42781a  PMID:23759873
  • Algar, W. R., Malonoski, A., Deschamps, J. R., Banco-Canosa, J. B., Susumu, K., Stewart, M. H., Johnson, B. J., Dawson, P. E., Medintz, I. L. Proteolytic activity at quantum dot-conjugates: kinetic analysis reveals enhanced enzyme activity and localized interfacial "hopping" Nano Letters  2012 12:3793-3802  DOI:10.1021/nl301727k  PMID:22731798
  • Stewart, M. H., Huston, A. L., Scott, A. M., Efros, A. L., Melinger, J. S., Gemmill, K. B., Trammell, S. A., Blanco-Canosa, J. B., Dawson, P. E., Medintz, I. L. Complex Förster energy transfer interactions between semiconductor quantum dots and a redox-active osmium assembly ACS Nano  2012 6:5330-5347  DOI:10.1021/nn301177h  PMID:22671940
  • Buckhout-White, S., Ancona, M., Oh, E., Deschamps, J. R., Stewart, M. H., Blanco-Canosa, J. B., Dawson, P. E., Goldman, E. R., Medintz, I. L. Multimodal characterization of a linear DNA-based nanostructure ACS Nano  2012 6:1026-1043  DOI:10.1021/nn204680r  PMID:22257317
  • Algar, W. R., Wegner, D., Huston, A. L., Blanco-Canosa, J. B., Stewart, M. H., Armstrong, A., Dawson, P. E., Hildebrandt, N., Medintz, I. L. Quantum dots as simultaneous acceptors and donors in time-gated Förster resonance energy transfer relays: characterization and biosensing Journal of the American Chemical Society  2012 134:1876-1891  DOI:10.1021/ja210162f  PMID:22220737
  • Morgner, F., Stufler, S., Geissler, D., Medintz, I. L., Algar, W. R., Susumu, K., Stewart, M. H., Blanco-Canosa, J. B., Dawson, P. E., Hildebrandt, N. Terbium to quantum dot FRET bioconjugates for clinical diagnostics: influence of human plasma on optical and assembly properties Sensors  2011 11:9667-9684  DOI:10.3390/s111009667  PMID:22163719  PMCID:PMC3231297
  • Oh, E., Delehanty, J. B., Sapsford, K. E., Susumu, K., Goswami, R., Blanco-Canosa, J. B., Dawson, P. E., Granek, J., Shoff, M., Zhang, Q., Goering, P. L., Huston, A., et al. Cellular uptake and fate of PEGylated gold nanoparticles is dependent on both cell-penetration peptides and particle size ACS Nano  2011 5:6434-6448  DOI:10.1021/nn201624c  PMID:21774456
  • Delehanty, J. B., Bradburne, C. E., Susumu, K., Boeneman, K., Mei, B. C., Farrell, D., Blanco-Canosa, J. B., Dawson, P. E., Mattoussi, H., Medintz, I. L. Spatiotemporal multicolor labeling of individual cells using peptide-functionalized quantum dots and mixed delivery techniques Journal of the American Chemical Society  2011 133:10482-10489  DOI:10.1021/ja200555z  PMID:21627173
  • Susumu, K., Oh, E., Delehanty, J. B., Blanco-Canosa, J. B., Johnson, B. J., Jain, V., Hervey, W. J., Algar, W. R., Boeneman, K., Dawson, P. E., Medintz, I. L. Multifunctional compact zwitterionic ligands for preparing robust biocompatible semiconductor quantum dots and gold nanoparticles Journal of the American Chemical Society  2011 133:9480-9496  DOI:10.1021/ja201919s  PMID:21612225
  • Algar, W. R., Prasuhn, D. E., Stewart, M. H., Jennings, T. L., Blanco-Canosa, J. B., Dawson, P. E., Medintz, I. L. The controlled display of biomolecules on nanoparticles: a challenge suited to bioorthogonal chemistry Bioconjugate Chemistry  2011 22:825-858  DOI:10.1021/bc200065z  PMID:21585205
  • Sapsford, K. E., Granek, J., Deschamps, J. R., Boeneman, K., Blanco-Canosa, J. B., Dawson, P. E., Susumu, K., Stewart, M. H., Medintz, I. L. Monitoring botulinum neurotoxin a activity with peptide-functionalized quantum dot resonance energy transfer sensors ACS Nano  2011 5:2687-2699  DOI:10.1021/nn102997b  PMID:21361387
  • Boeneman, K., Prasuhn, D. E., Blanco-Canosa, J. B., Dawson, P. E., Melinger, J. S., Ancona, M., Stewart, M. H., Susumu, K., Huston, A., Medintz, I. L. Self-assembled quantum dot-sensitized multivalent DNA photonic wires Journal of the American Chemical Society  2010 132:18177-18190  DOI:10.1021/ja106465x  PMID:21141858
  • Boeneman, K., Deschamps, J. R., Buckhout-White, S., Prasuhn, D. E., Blanco-Canosa, J. B., Dawson, P. E., Stewart, M. H., Susumu, K., Goldman, E. R., Ancona, M., Medintz, I. L. Quantum dot DNA bioconjugates: attachment chemistry strongly influences the resulting composite architecture ACS Nano  2010 4:7253-7266  DOI:10.1021/nn1021346  PMID:21082822  PMCID:PMC4383186
  • Medintz, I. L., Stewart, M. H., Trammell, S. A., Susumu, K., Delehanty, J. B., Mei, B. C., Melinger, J. S., Blanco-Canosa, J. B., Dawson, P. E., Mattoussi, H. Quantum-dot/dopamine bioconjugates function as redox coupled assemblies for in vitro and intracellular pH sensing Nature Materials  2010 9:676-684  DOI:10.1038/nmat2811  PMID:20651808
  • Blanco-Canosa, J. B., Medintz, I. L., Farrell, D., Mattoussi, H., Dawson, P. E. Rapid covalent ligation of fluorescent peptides to water solubilized quantum dots Journal of the American Chemical Society  2010 132:10027-10033  DOI:10.1021/ja910988d  PMID:20597509  PMCID:PMC3182822
  • Stewart, M. H., Susumu, K., Mei, B. C., Medintz, I. L., Delehanty, J. B., Blanco-Canosa, J. B., Dawson, P. E., Mattoussi, H. Multidentate poly(ethylene glycol) ligands provide colloidal stability to semiconductor and metallic nanocrystals in extreme conditions Journal of the American Chemical Society  2010 132:9804-9813  DOI:10.1021/ja102898d  PMID:20578776
  • Oh, E., Susumu, K., Blanco-Canosa, J. B., Medintz, I. L., Dawson, P. E., Mattoussi, H. Preparation of stable maleimide-functionalized Au nanoparticles and their use in counting surface ligands Small  2010 6:1273-1278  DOI:10.1002/smll.201000279  PMID:20486227
  • Prasuhn, D. E., Deschamps, J. R., Susumu, K., Stewart, M. H., Boeneman, K., Blanco-Canosa, J. B., Dawson, P. E., Medintz, I. L. Polyvalent display and packing of peptides and proteins on semiconductor quantum dots: predicted versus experimental results Small  2010 6:555-564  DOI:10.1002/smll.200901845  PMID:20077423
  • Sapsford, K. E., Blanco-Canosa, J. B., Dawson, P. E., Medintz, I. L. Detection of HIV-1 specific monoclonal antibodies using enhancement of dye-labeled antigenic peptides Bioconjugate Chemistry  2010 21:393-398  DOI:10.1021/bc9003712  PMID:20058910
  • Prasuhn, D. E., Blanco-Canosa, J. B., Vora, G. J., Delehanty, J. B., Susumu, K., Mei, B. C., Dawson, P. E., Medintz, I. L. Combining chemoselective ligation with polyhistidine-driven self-assembly for the modular display of biomolecules on quantum dots ACS Nano  2010 4:267-278  DOI:10.1021/nn901393v  PMID:20099912  PMCID:PMC4756922
  • Delehanty, J. B., Bradburne, C. E., Boeneman, K., Susumu, K., Farrell, D., Mei, B. C., Blanco-Canosa, J. B., Dawson, G., Dawson, P. E., Mattoussi, H., Medintz, I. L. Delivering quantum dot-peptide bioconjugates to the cellular cytosol: escaping from the endolysosomal system Integrative Biology  2010 2:265-277  DOI:10.1039/c0ib00002g  PMID:20535418
  • Prasuhn, D. E., Feltz, A., Blanco-Canosa, J. B., Susumu, K., Stewart, M. H., Mei, B. C., Yakovlev, A. V., Loukov, C., Mallet, J. M., Oheim, M., Dawson, P. E., Medintz, I. L. Quantum dot peptide biosensors for monitoring caspase 3 proteolysis and calcium ions ACS Nano  2010 4:5487-5497  DOI:10.1021/nn1016132  PMID:20822159
  • Medintz, I. L., Farrell, D., Susumu, K., Trammell, S. A., Deschamps, J. R., Brunel, F. M., Dawson, P. E., Mattoussi, H. Multiplex charge-transfer interactions between quantum dots and peptide-bridged ruthenium complexes Analytical Chemistry  2009 81:4831-4839  DOI:10.1021/ac900412j  PMID:19445483
  • Medintz, I. L., Pons, T., Trammell, S. A., Grimes, A. F., English, D. S., Blanco-Canosa, J. B., Dawson, P. E., Mattoussi, H. Interactions between redox complexes and semiconductor quantum dots coupled via a peptide bridge Journal of the American Chemical Society  2008 130:16745-16756  DOI:10.1021/ja805456x  PMID:19049466  PMCID:PMC2779033
  • Medintz, I. L., Pons, T., Delehanty, J. B., Susumu, K., Brunel, F. M., Dawson, P. E., Mattoussi, H. Intracellular delivery of quantum dot-protein cargos mediated by cell penetrating peptides Bioconjugate Chemistry  2008 19:1785-1795  DOI:10.1021/bc800089r  PMID:18681468
  • Sapsford, K. E., Pons, T., Medintz, I. L., Higashiya, S., Brunel, F. M., Dawson, P. E., Mattoussi, H. Kinetics of metal-affinity driven self-assembly between proteins or peptides and CdSe-ZnS quantum dots Journal of Physical Chemistry C  2007 111:11528-11538  DOI:10.1021/jp073550t
  • Clapp, A. R., Pons, T., Medintz, I. L., Delehanty, J. B., Melinger, J. S., Tiefenbrunn, T., Dawson, P. E., Fisher, B. R., O'Rourke, B., Mattoussi, H. Two-photon excitation of quantum-dot-based fluorescence resonance energy transfer and its applications Advanced Materials  2007 19:1921-1926  DOI:10.1002/adma.200602036
  • Delehanty, J. B., Medintz, I. L., Pons, T., Brunel, F. M., Dawson, P. E., Mattoussi, H. Self-assembled quantum dot-peptide bioconjugates for selective intracellular delivery Bioconjugate Chemistry  2006 17:920-927  DOI:10.1021/bc060044i  PMID:16848398  PMCID:PMC2519024
  • Medintz, I. L., Clapp, A. R., Brunel, F. M., Tiefenbrunn, T., Uyeda, H. T., Chang, E. L., Deschamps, J. R., Dawson, P. E., Mattoussi, H. Proteolytic activity monitored by fluorescence resonance energy transfer through quantum-dot-peptide conjugates Nature Materials  2006 5:581-589  DOI:10.1038/nmat1676  PMID:16799548
  • Medintz, I. L., Sapsford, K. E., Konnert, J. H., Chatterji, A., Lin, T. W., Johnson, J. E., Mattoussi, H. Decoration of discretely immobilized cowpea mosaic virus with luminescent quantum dots Langmuir  2005 21:5501-5510  DOI:10.1021/la0468287  PMID:15924481
  • Scherer, J. R., Paegel, B. M., Wedemayer, G. J., Emrich, C. A., Lo, J., Medintz, I. L., Mathies, R. A. High-pressure gel loader for capillary array electrophoresis microchannel plates Biotechniques  2001 31:1150-1154  PMID:11730021
  • Medintz, I. L., Paegel, B. M., Blazej, R. G., Emrich, C. A., Berti, L., Scherer, J. R., Mathies, R. A. High-performance genetic analysis using microfabricated capillary array electrophoresis microplates Electrophoresis  2001 22:3845-3856  DOI:10.1002/1522-2683(200110)22:18<3845::aid-elps3845>3.0.co;2-0  PMID:11700713
  • Medintz, I. L., Paegel, B. M., Mathies, R. A. Microfabricated capillary array electrophoresis DNA analysis systems Journal of Chromatography A  2001 924:265-270  DOI:10.1016/s0021-9673(01)00852-4  PMID:11521873