recent publications

• academic article

  • Inagaki, H., Tsuruoka, H., Hornsby, M., Lesley, S. A., Spraggon, G., Ellman, J. A. Characterization and optimization of selective, nonpeptidic inhibitors of cathepsin S with an unprecedented binding mode Journal of Medicinal Chemistry  2007 50:2693-2699  DOI:10.1021/jm070111+  PMID:17469812
  • Rech, J. C., Yato, M., Duckett, D., Ember, B., LoGrasso, P. V., Bergman, R. G., Ellman, J. A. Synthesis of potent bicyclic bisarylimidazole c-jun N-terminal kinase inhibitors by catalytic C-H bond activation Journal of the American Chemical Society  2007 129:490-491  DOI:10.1021/ja0676004  PMID:17227002  PMCID:PMC2556147
  • Boitano, A., Emal, C. D., Leonetti, F., Blatt, N. B., Dineen, T. A., Ellman, J. A., Roush, W. R., Opipari, A. W., Glick, G. D. Structure activity studies of a novel cytotoxic benzodiazepine Bioorganic & Medicinal Chemistry Letters  2003 13:3327-3330  DOI:10.1016/s0960-894x(03)00683-8  PMID:12951119
  • Choi, C. Y. H., Schneider, E. L., Kim, J. M., Gluzman, I. Y., Goldberg, D. E., Ellman, J. A., Marletta, M. A. Interference with heme binding to histidine-rich protein-2 as an antimalarial strategy Chemistry & Biology  2002 9:881-889  DOI:10.1016/s1074-5521(02)00183-7  PMID:12204687
  • Cook, S. N., Jack, W. E., Xiong, X. F., Danley, L. E., Ellman, J. A., Schultz, P. G., Noren, C. J. Photochemically initiated protein splicing Angewandte Chemie-International Edition  1995 34:1629-1630  DOI:10.1002/anie.199516291
  • Ellman, J. A., Volkman, B. F., Mendel, D., Schultz, P. G., Wemmer, D. E. Site-specific isotopic labeling of proteins for NMR studies Journal of the American Chemical Society  1992 114:7959-7961  DOI:10.1021/ja00046a080
  • Mendel, D., Ellman, J. A., Chang, Z. Y., Veenstra, D. L., Kollman, P. A., Schultz, P. G. Probing protein stability with unnatural amino acids Science  1992 256:1798-1802  DOI:10.1126/science.1615324  PMID:1615324
  • Ellman, J. A., Mendel, D., Schultz, P. G. Site-specific incorporation of novel backbone structures into proteins Science  1992 255:197-200  DOI:10.1126/science.1553546  PMID:1553546
  • Robertson, S. A., Ellman, J. A., Schultz, P. G. A general and efficient route for chemical aminoacylation of transfer RNAs Journal of the American Chemical Society  1991 113:2722-2729  DOI:10.1021/ja00007a055
  • Mendel, D., Ellman, J. A., Schultz, P. G. Construction of a light-activated protein by unnatural amino acid mutagenesis Journal of the American Chemical Society  1991 113:2758-2760  DOI:10.1021/ja00007a063