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Tyrosine hydroxylase, the rate-limiting enzyme in catecholamine biosynthesis - discovery of common human genetic variants governing transcription, autonomic activity, and blood pressure in vivo

Academic Article
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Overview

authors

  • Rao, F.
  • Zhang, L.
  • Wessel, J.
  • Zhang, K.
  • Wen, G.
  • Kennedy, B. P.
  • Rana, B. K.
  • Das, M.
  • Rodriguez-Flores, J. L.
  • Smith, D. W.
  • Cadman, P. E.
  • Salem, R. M.
  • Mahata, S. K.
  • Schork, Nicholas
  • Taupenot, L.
  • Ziegler, M. G.
  • O'Connor, D. T.

publication date

  • 2007

journal

  • Circulation  Journal

subject areas

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Algorithms
  • Autonomic Nervous System
  • Blood Pressure
  • Cardiovascular Diseases
  • Catecholamines
  • Genetic Predisposition to Disease
  • Genetic Variation
  • Humans
  • Kinetics
  • Middle Aged
  • Polymorphism, Single Nucleotide
  • Transcription, Genetic
  • Twins, Dizygotic
  • Twins, Monozygotic
  • Tyrosine 3-Monooxygenase
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Research

keywords

  • catecholamines
  • genetics
  • nervous system, autonomic
  • nervous system, sympathetic
  • norepinephrine
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Identity

International Standard Serial Number (ISSN)

  • 0009-7322

Digital Object Identifier (DOI)

  • 10.1161/circulationaha.106.682302

PubMed ID

  • 17698732
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Additional Document Info

start page

  • 993

end page

  • 1006

volume

  • 116

issue

  • 9

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