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Synthesis and SAR of 2-phenoxypyridines as novel c-Jun N-terminal kinase inhibitors

Academic Article
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  • Research
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Overview

authors

  • Song, X. Y.
  • Chen, W. M.
  • Lin, L.
  • Ruiz, C. H.
  • Cameron, Michael
  • Duckett, Derek
  • Kamenecka, Theodore

publication date

  • December 2011

journal

  • Bioorganic & Medicinal Chemistry Letters  Journal

subject areas

  • Drug Design
  • Enzyme Activation
  • Inhibitory Concentration 50
  • JNK Mitogen-Activated Protein Kinases
  • Models, Molecular
  • Molecular Structure
  • Protein Kinase Inhibitors
  • Pyridines
  • Pyrimidines
  • Structure-Activity Relationship
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Research

keywords

  • JNK
  • Kinase inhibitor
  • Phenoxypyridine
  • c-Jun
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Identity

International Standard Serial Number (ISSN)

  • 0960-894X

Digital Object Identifier (DOI)

  • 10.1016/j.bmcl.2011.09.090

PubMed ID

  • 22004719
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Additional Document Info

start page

  • 7072

end page

  • 7075

volume

  • 21

issue

  • 23

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