recent publications

• academic article

  • Roth, D. M., Hutt, D. M., Tong, J., Bouchecareilh, M., Wang, N., Seeley, T., Dekkers, J. F., Beekman, J. M., Garza, D., Drew, L., Masliah, E., Morimoto, R. I., et al. Modulation of the maladaptive stress response to manage diseases of protein folding PLoS Biology  2014 12  DOI:10.1371/journal.pbio.1001998  PMID:25406061  PMCID:PMC4236052
  • Roth, D. M., Balch, W. E. Q-bodies monitor the quinary state of the protein fold Nature Cell Biology  2013 15:1137-1139  DOI:10.1038/ncb2857  PMID:24084862
  • Hutt, D. M., Roth, D. M., Chalfant, M. A., Youker, R. T., Matteson, J., Brodsky, J. L., Balch, W. E. FK506 binding protein 8 peptidylprolyl isomerase activity manages a late stage of cystic fibrosis transmembrane conductance regulator (CFTR) folding and stability Journal of Biological Chemistry  2012 287:21914-21925  DOI:10.1074/jbc.M112.339788  PMID:22474283  PMCID:PMC3381152
  • Roth, D. M., Balch, W. E. Modeling general proteostasis: Proteome balance in health and disease Current Opinion in Cell Biology  2011 23:126-134  DOI:10.1016/j.ceb.2010.11.001  PMID:21131189  PMCID:PMC3077458
  • Balch, W. E., Roth, D. M., Hutt, D. M. Emergent properties of proteostasis in managing cystic fibrosis Cold Spring Harbor Perspectives in Biology  2011 3:a004499  DOI:10.1101/cshperspect.a004499  PMID:21421917  PMCID:PMC3039536
  • Smith, J. B., Roth, D. M., Lefer, A. M., Petasis, N. A., Nicolaou, K. C. Modulation of leukotriene synthesis and actions by synthetic derivatives of arachidonic-acid Prostaglandins  1985 29:765-771  DOI:10.1016/0090-6980(85)90136-4  PMID:4011927
  • Roth, D. M., Lefer, A. M., Smith, J. B., Nicolaou, K. C. Anti-thromboxane-a2 actions of pinane thromboxane-a2 derivatives Prostaglandins Leukotrienes and Medicine  1982 9:503-509  DOI:10.1016/0262-1746(82)90031-2  PMID:6960376