recent publications

• academic article

  • Broide, R. S., Trembleau, A., Ellison, J. A., Cooper, J., Lo, D., Young, W. G., Morrison, J. H., Bloom, F. E. Standardized quantitative in situ hybridization using radioactive oligonucleotide probes for detecting relative levels of mrna transcripts verified by real-time pcr Brain Research  2004 1000:211-222  DOI:10.1016/j.brainres.2003.11.069  PMID:15053970
  • Thomas, E. A., George, R. C., Danielson, P. E., Nelson, P. A., Warren, A. J., Lo, D., Sutcliffe, J. G. Antipsychotic drug treatment alters expression of mrnas encoding lipid metabolism-related proteins Molecular Psychiatry  2003 8:983-993  DOI:10.1038/sj.mp.4001425  PMID:14647396
  • Oldstone, M. B. A., Race, R., Thomas, D., Lewicki, H., Homann, D., Smelt, S., Holz, A., Koni, P., Lo, D., Chesebro, B., Flavell, R. Lymphotoxin-alpha- and lymphotoxin-beta-deficient mice differ in susceptibility to scrapie: Evidence against dendritic cell involvement in neuroinvasion Journal of Virology  2002 76:4357-4363  DOI:10.1128/jvi.76.9.4357-4363.2002  PMID:11932402
  • Kreuwel, H. T. C., Biggs, J. A., Pilip, I. M., Pamer, E. G., Lo, D., Sherman, L. A. Defective CD8+ T cell peripheral tolerance in nonobese diabetic mice Journal of Immunology  2001 167:1112-1117  PMID:11441123
  • Marzo, A. L., Lake, R. A., Lo, D., Sherman, L., McWilliam, A., Nelson, D., Robinson, B. W. S., Scott, B. Tumor antigens are constitutively presented in the draining lymph nodes Journal of Immunology  1999 162:5838-5845  PMID:10229818
  • Carson, M. J., Reilly, C. R., Sutcliffe, J. G., Lo, D. Disproportionate recruitment of cd8(+) t cells into the central nervous system by professional antigen-presenting cells American Journal of Pathology  1999 154:481-494  DOI:10.1016/s0002-9440(10)65294-7  PMID:10027406
  • Sim, B. C., Aftahi, N., Reilly, C., Bogen, B., Schwartz, R. H., Gascoigne, N. R. J., Lo, D. Thymic skewing of the cd4/cd8 ratio maps with the t-cell receptor alpha-chain locus Current Biology  1998 8:701-704  DOI:10.1016/s0960-9822(98)70276-3  PMID:9637921
  • Sim, B. C., Lo, D., Gascoigne, N. R. J. Preferential expression of tcr v alpha regions in cd4/cd8 subsets: Class discrimination or co-receptor recognition? Immunology Today  1998 19:276-282  DOI:10.1016/s0167-5699(98)01257-2  PMID:9639993
  • Carson, M. J., Reilly, C. R., Sutcliffe, J. G., Lo, D. Mature microglia resemble immature antigen-presenting cells Glia  1998 22:72-85  DOI:10.1002/(sici)1098-1136(199801)22:1<72::aid-glia7>3.0.co;2-a  PMID:9436789
  • DeKoning, J., DiMolfetto, L., Reilly, C., Wei, Q., Havran, W. L., Lo, D. Thymic cortical epithelium is sufficient for the development of mature t cells in relb-deficient mice Journal of Immunology  1997 158:2558-2566  PMID:9058787
  • Morgan, D. J., Liblau, R., Scott, B., Fleck, S., McDevitt, H. O., Sarvetnick, N., Lo, D., Sherman, L. A. CD8(+) T cell-mediated spontaneous diabetes in neonatal mice Journal of Immunology  1996 157:978-983  PMID:8757600
  • Degermann, S., Surh, C. D., Glimcher, L. H., Sprent, J., Lo, D. B7 expression on thymic medullary epithelium correlates with epithelium-mediated deletion of v-beta-5(+) thymocytes Journal of Immunology  1994 152:3254-3263  PMID:7511640
  • Lewandowski, G. A., Lo, D., Bloom, F. E. Interference with major histocompatibility complex class-ii-restricted antigen presentation in the brain by herpes-simplex virus type-1 - a possible mechanism of evasion of the immune-response Proceedings of the National Academy of Sciences of the United States of America  1993 90:2005-2009  DOI:10.1073/pnas.90.5.2005  PMID:8095338
  • Lo, D., Freedman, J., Hesse, S., Palmiter, R. D., Brinster, R. L., Sherman, L. A. Peripheral tolerance to an islet cell-specific hemagglutinin transgene affects both CD4+ and CD8+ T cells European Journal of Immunology  1992 22:1013-1022  DOI:10.1002/eji.1830220421  PMID:1348026
  • Surh, C. D., Gao, E. K., Kosaka, H., Lo, D., Ahn, C., Murphy, D. B., Karlsson, L., Peterson, P., Sprent, J. Two subsets of epithelial cells in the thymic medulla Journal of Experimental Medicine  1992 176:495-505  DOI:10.1084/jem.176.2.495  PMID:1500857  PMCID:PMC2119314
  • Lo, D., Freedman, J., Hesse, S., Brinster, R. L., Sherman, L. Peripheral tolerance in transgenic mice: tolerance to class II MHC and non-MHC transgene antigens Immunological Reviews  1991 122:87-102  DOI:10.1111/j.1600-065X.1991.tb00598.x  PMID:1682240