articles
- Progress toward the development of the small molecule equivalent of small interfering RNA. 56:63-71. 2020
- Recent advances in the chemoenzymatic synthesis of bioactive natural products. 55:111-118. 2020
- Aptamer-based and aptazyme-based riboswitches in mammalian cells. 52:72-78. 2019
- Editorial overview: Mammalian synthetic biology: from devices to multicellular systems. 52:A1-a2. 2019
- Enzymatic C-H functionalizations for natural product synthesis. 49:25-32. 2019
- Sphingolipids and membrane targets for therapeutics. 50:19-28. 2019
- Understanding molecular mechanisms of disease through spatial proteomics. 48:19-25. 2019
- Editorial overview: Expanding the genetic alphabet and code. 46:A1-A2. 2018
- Editorial overview: Synthetic biomolecules. 46:A3-A4. 2018
- Expansion of the genetic code via expansion of the genetic alphabet. 46:196-202. 2018
- Covalent inhibitors: an opportunity for rational target selectivity. 39:54-63. 2017
- Visualizing glycans on single cells and tissues-Visualizing glycans on single cells and tissues. 39:39-45. 2017
- A current pharmacologic agent versus the promise of next generation therapeutics to ameliorate protein misfolding and/or aggregation diseases. 32:10-21. 2016
- Editorial overview: Omics: The maturation of chemical biology. 30:V-VI. 2016
- Harnessing cyanine photooxidation: from slowing photobleaching to near-IR uncaging. 33:117-125. 2016
- Harvesting the biosynthetic machineries that cultivate a variety of indispensable plant natural products. 31:66-73. 2016
- Non-natural carbenoid and nitrenoid insertion reactions catalyzed by heme proteins. 35:124-132. 2016
- The expanding world of DNA and RNA. 34:80-87. 2016
- Folding and function in α/β-peptides: targets and therapeutic applications. 28:75-82. 2015
- PNA-encoded chemical libraries. 26:8-15. 2015
- Editorial overview: Omics: Methods to monitor and manipulate biological systems: recent advances in 'omics'. 24:v-vii. 2015
- Homogeneously modified immunoglobulin domains for therapeutic application. 28:66-74. 2015
- Selection of multiple agonist antibodies from intracellular combinatorial libraries reveals that cellular receptors are functionally pleiotropic. 26:1-7. 2015
- Small molecule chemical probes of microRNA function. 24:97-103. 2015
- Biofuels for the 21st century. 17:436-438. 2013
- Echinomycin biosynthesis. 17:537-545. 2013
- Engineering fatty acid biosynthesis in microalgae for sustainable biodiesel. 17:496-505. 2013
- Pairwise interactions in collagen and the design of heterotrimeric helices. 17:960-967. 2013
- Peptidomics methods for the identification of peptidase-substrate interactions. 17:83-89. 2013
- Synthesis of sialic acid-containing saccharides. 17:1030-1038. 2013
- In vivo chemistry. 17:717-718. 2013
- Protein conjugation with genetically encoded unnatural amino acids. 17:412-419. 2013
- Targeting unfolded protein response signaling pathways to ameliorate protein misfolding diseases. 17:346-352. 2013
- Successes and failures in modular genetic engineering. 16:329-336. 2012
- Bacterial diterpene synthases: New opportunities for mechanistic enzymology and engineered biosynthesis. 16:132-141. 2012
- Mechanisms of S-nitrosothiol formation and selectivity in nitric oxide signaling. 16:498-506. 2012
- Optimizing non-natural protein function with directed evolution. 15:201-210. 2011
- Proteomic analysis of polyketide and nonribosomal peptide biosynthesis. 15:48-56. 2011
- Role of natural product diversity in chemical biology. 15:350-354. 2011
- Small molecule modulators of antioxidant response pathway. 15:162-173. 2011
- Chemical 'omics' approaches for understanding protein cysteine oxidation in biology. 15:88-102. 2011
- Inside the 40s ribosome assembly machinery. 15:657-663. 2011
- Chemically modified viruses: principles and applications. 14:810-817. 2010
- Development of antibody surrogates for the treatment of cancers and autoimmune disease. 14:721-727. 2010
- Microfluidic landscapes for evolution. 14:568-573. 2010
- Privileged scaffolds for library design and drug discovery. 14:347-361. 2010
- Synthetic receptors with antibody-like binding affinities. 14:713-720. 2010
- Dissecting protein function and signaling using protein microarrays. 13:398-405. 2009
- Recent advances in carbohydrate-based vaccines. 13:354-359. 2009
- The promise and challenge of '-omic' approaches. 13:501-502. 2009
- Expanding the functional diversity of proteins through cysteine oxidation. 12:746-754. 2008
- Expanding the scope of chemoselective peptide ligations in chemical biology. 12:760-766. 2008
- Glycan arrays: Biological and medical applications. 12:86-92. 2008
- Mass spectrometry for proteomics. 12:483-490. 2008
- A chemical approach to stem cell biology. 11:252-258. 2007
- Aptasensors for biosecurity applications. 11:316-328. 2007
- Cures for neglected diseases: alternative strategies for finding drugs. 11:410-411. 2007
- Site-specific protein modification: advances and applications. 11:12-19. 2007
- The interdependence between screening methods and screening libraries. 11:244-251. 2007
- Strategies for the preparation of homogenous glycoproteins. 10:638-644. 2006
- Adding amino acids to the genetic repertoire. 9:548-554. 2005
- Genomic studies of transcription factor-DNA interactions. 9:38-45. 2005
- Global strategies to integrate the proteome and metabolome. 9:62-68. 2005
- Ligand discrimination in soluble guanylate cyclase and the h-nox family of heme sensor proteins. 9:441-446. 2005
- Covalent capture: a natural complement to self-assembly. 8:604-609. 2004
- Proteomics and genomics. Editorial overview. 8:1-2. 2004
- Cell surface biology mediated by low affinity multivalent protein-glycan interactions. 8:617-625. 2004
- Editorial overview: Challenge complex biological function with smart chemistry. 8:567-569. 2004
- Minimal self-replicating systems. 8:634-639. 2004
- The development and application of methods for activity-based protein profiling. 8:54-59. 2004
- Proyl peptidases: a serine protease subfamily with high potential for drug discovery. 7:496-504. 2003
- Advances in pain therapeutics. 7:452-456. 2003
- Beyond A, C, G and T: augmenting nature's alphabet. 7:727-733. 2003
- Fatty acid amide hydrolase: An emerging therapeutic target in the endocannabinoid system. 7:469-475. 2003
- Polyketide biosynthesis beyond the type i, ii and iii polyketide synthase paradigms. 7:285-295. 2003
- Sphingosine 1-phosphate pathway therapeutics: A lipid ligand-receptor paradigm. 7:461-468. 2003
- Formats for combinatorial synthesis: Solid-phase, liquid-phase and surface. 6:339-346. 2002
- Insights into properties and energetics of iron-sulfur proteins from simple clusters to nitrogenase. 6:259-273. 2002
- Recent advances in the synthesis, design and selection of cysteine protease inhibitors. 6:459-465. 2002
- The genesis of high-throughput structure-based drug discovery using protein crystallography. 6:704-710. 2002
- Chemical strategies for the global analysis of protein function. 4:663-668. 2000
- Design of novel sequence-specific DNA-binding proteins. 4:34-39. 2000
- Interaction, assembly and processing: life on an interface. 4:13-15. 2000
- Mechanisms. Mechanisms of catalysis: macroscopic and microscopic progress. Editorial overview. 4:531-532. 2000
- Rna as a target for small molecules. 4:678-686. 2000
- The aging process: where are the drug opportunities?. 4:371-376. 2000
- Catalysis by nitric oxide synthase. 2:656-663. 1998
- Catalytic antibodies. 2:138-144. 1998
- Rational treatment of addiction. 2:541-547. 1998
- Autocatalytic networks: The transition from molecular self-replication to molecular ecosystems. 1:491-496. 1997
- Synthesis on soluble polymers: New reactions and the construction of small molecules. 1:107-113. 1997