Scripps VIVO scripps research logo

  • Index
  • Log in
  • Home
  • People
  • Organizations
  • Research
  • Events
Search form
As of April 1st VIVO Scientific Profiles will no longer updated for faculty, and the link to VIVO will be removed from the library website. Faculty profile pages will continue to be updated via Interfolio. VIVO will continue being used behind the scenes to update graduate student profiles. Please contact helplib@scripps.edu if you have questions.
How to download citations from VIVO | Alternative profile options

Safety of helicopter transport and out-of-hospital intravenous fibrinolytic therapy in patients with evolving myocardial-infarction

Academic Article
uri icon
  • Overview
  • Identity
  • Additional Document Info
  • View All
scroll to property group menus

Overview

authors

  • Topol, Eric
  • Fung, A. Y.
  • Kline, E.
  • Kaplan, L.
  • Landis, D.
  • Strozeski, M.
  • Burney, R. E.
  • Pitt, B.
  • Oneill, W. W.

publication date

  • 1986

journal

  • Catheterization and Cardiovascular Diagnosis  Journal

abstract

  • Of 150 consecutive patients with acute myocardial infarction transported by helicopter for acute intervention, 55 had intravenous thrombolytic therapy (tissue plasminogen activator in 12, streptokinase in 43) initiated prior to transfer. Patients were transported 55 +/- 10 ground miles in 17 +/- 6 minutes and no patient died or experienced bleeding or hemodynamic instability during transfer. Patients receiving thrombolytic therapy had a higher incidence of arrhythmias during transit compared to the untreated group, ventricular tachycardia in six and third-degree atrioventricular block in one compared to ventricular tachycardia in one patient, respectively (p = 0.005). However, these arrhythmias were transient and did not require cardioversion, temporary pacing, or further antiarrhythmic medical treatment. Chest pain was relieved or decreased more frequently in the patients receiving thrombolytic therapy vs. those untreated; 21 of 55 vs. 21 of 95 respectively (p = 0.04). Immediate coronary angiography confirmed a higher incidence and more complete infarct vessel patency (34/55 vs. 30/95) in the patients receiving tissue plasminogen activator or streptokinase (p less than 0.001). Thus, helicopter transfer of patients with evolving myocardial infarction is safe, and early initiation of thrombolytic therapy is associated with increased infarct vessel patency and benign reperfusion arrhythmias.

subject areas

  • Aircraft
  • Arrhythmias, Cardiac
  • Female
  • Humans
  • Infusions, Parenteral
  • Male
  • Middle Aged
  • Myocardial Infarction
  • Safety
  • Streptokinase
  • Tachycardia
  • Tissue Plasminogen Activator
  • Transportation of Patients
scroll to property group menus

Identity

International Standard Serial Number (ISSN)

  • 0098-6569

PubMed ID

  • 3089627
scroll to property group menus

Additional Document Info

start page

  • 151

end page

  • 155

volume

  • 12

issue

  • 3

©2022 The Scripps Research Institute | Terms of Use | Powered by VIVO

  • About
  • Contact Us
  • Support