recent publications

• academic article

  • Yin, Y., Lin, L., Ruiz, C., Khan, S., Cameron, M. D., Grant, W., Pocas, J., Eid, N., Park, H., Schroter, T., Lograsso, P. V., Feng, Y. Synthesis and biological evaluation of urea derivatives as highly potent and selective rho kinase inhibitors Journal of Medicinal Chemistry  2013 56:3568-3581  DOI:10.1021/jm400062r  PMID:23570561
  • Chowdhury, S., Chen, Y. T., Fang, X. G., Grant, W., Pocas, J., Cameron, M. D., Ruiz, C., Lin, L., Park, H., Schroter, T., Bannister, T. D., LoGrasso, P. V., et al. Amino acid derived quinazolines as Rock/PKA inhibitors Bioorganic & Medicinal Chemistry Letters  2013 23:1592-1599  DOI:10.1016/j.bmcl.2013.01.109  PMID:23416002
  • Fang, X. G., Yin, Y., Chen, Y. T., Yao, L., Wang, B., Cameron, M. D., Lin, L., Khan, S., Ruiz, C., Schroter, T., Grant, W., Weiser, A., et al. Tetrahydroisoquinoline derivatives as highly selective and potent Rho kinase inhibitors Journal of Medicinal Chemistry  2010 53:5727-5737  DOI:10.1021/jm100579r  PMID:20684608
  • Yin, Y., Cameron, M. D., Lin, L., Khan, S., Schroter, T., Grant, W., Pocas, J., Chen, Y. T., Schurer, S., Pachori, A., LoGrasso, P., Feng, Y. B. Discovery of potent and selective urea-based ROCK inhibitors and their effects on intraocular pressure in rats ACS Medicinal Chemistry Letters  2010 1:175-179  DOI:10.1021/ml1000382  PMID:24900192  PMCID:PMC4007833
  • Sessions, E. H., Smolinski, M., Wang, B., Frackowiak, B., Chowdhury, S., Yin, Y., Chen, Y. T., Ruiz, C., Lin, L., Pocas, J., Schroter, T., Cameron, M. D., et al. The development of benzimidazoles as selective Rho kinase inhibitors Bioorganic & Medicinal Chemistry Letters  2010 20:1939-1943  DOI:10.1016/j.bmcl.2010.01.124  PMID:20167489
  • Yin, Y., Lin, L., Ruiz, C., Cameron, M. D., Pocas, J., Grant, W., Schroter, T., Chen, W. M., Duckett, D., Schurer, S., LoGrasso, P., Feng, Y. B. Benzothiazoles as Rho-associated kinase (ROCK-II) inhibitors Bioorganic & Medicinal Chemistry Letters  2009 19:6686-6690  DOI:10.1016/j.bmcl.2009.09.115  PMID:19837589
  • Sessions, E. H., Yin, Y., Bannister, T. D., Weiser, A., Griffin, E., Pocas, J., Cameron, M. D., Ruiz, C., Lin, L., Schurer, S. C., Schroter, T., LoGrasso, P., et al. Benzimidazole- and benzoxazole-based inhibitors of Rho kinase Bioorganic & Medicinal Chemistry Letters  2008 18:6390-6393  DOI:10.1016/j.bmcl.2008.10.095  PMID:18996009