recent publications
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academic article
- Sui, Z., Nowak, R. B., Sanada, C., Halene, S., Krause, D. S., Fowler, V. M. Regulation of actin polymerization by tropomodulin-3 controls megakaryocyte actin organization and platelet biogenesis Blood 2015 126:520-530 DOI:10.1182/blood-2014-09-601484 PMID:25964668 PMCID:PMC4513252
- Cheng, C., Nowak, R. B., Gao, J., Sun, X., Biswas, S. K., Lo, W. K., Mathias, R. T., Fowler, V. M. Lens ion homeostasis relies on the assembly and/or stability of large connexin 46 gap junction plaques on the broad sides of differentiating fiber cells American Journal of Physiology-Cell Physiology 2015 308:C835-C847 DOI:10.1152/ajpcell.00372.2014 PMID:25740157 PMCID:PMC4436989
- Gokhin, D. S., Nowak, R. B., Khoory, J. A., de la Piedra, A., Ghiran, I. C., Fowler, V. M. Dynamic actin filaments control the mechanical behavior of the human red blood cell membrane Molecular Biology of the Cell 2015 26:1699-1710 DOI:10.1091/mbc.E14-12-1583 PMID:25717184 PMCID:PMC4436781
- McKeown, C. R., Nowak, R. B., Gokhin, D. S., Fowler, V. M. Tropomyosin is required for cardiac morphogenesis, myofibril assembly, and formation of adherens junctions in the developing mouse embryo Developmental Dynamics 2014 243:800-817 DOI:10.1002/dvdy.24115 PMID:24500875 PMCID:PMC4031292
- Sui, Z., Nowak, R. B., Bacconi, A., Kim, N. E., Liu, H., Li, J., Wickrema, A., An, X. L., Fowler, V. M. Tropomodulin3-null mice are embryonic lethal with anemia due to impaired erythroid terminal differentiation in the fetal liver Blood 2014 123:758-767 DOI:10.1182/blood-2013-03-492710 PMID:24159174 PMCID:PMC3907761
- Gokhin, D. S., Nowak, R. B., Kim, N. E., Arnett, E. E., Chen, A. C., Sah, R. L., Clark, J. I., Fowler, V. M. Tmod1 and CP49 synergize to control the fiber cell geometry, transparency, and mechanical stiffness of the mouse lens PLoS One 2012 7:e48734 DOI:10.1371/journal.pone.0048734 PMID:23144950 PMCID:PMC3492431
- Nowak, R. B., Fowler, V. M. Tropomodulin 1 constrains fiber cell geometry during elongation and maturation in the lens cortex Journal of Histochemistry and Cytochemistry 2012 60:414-427 DOI:10.1369/0022155412440881 PMID:22473940 PMCID:PMC3393074
- Yamashiro, S., Gokhin, D. S., Kimura, S., Nowak, R. B., Fowler, V. M. Tropomodulins: pointed-end capping proteins that regulate actin filament architecture in diverse cell types Cytoskeleton 2012 69:337-370 DOI:10.1002/cm.21031 PMID:22488942 PMCID:PMC3444156
- Leonard, M., Zhang, L. P., Zhai, N., Cader, A., Chan, Y., Nowak, R. B., Fowler, V. M., Menko, A. S. Modulation of N-cadherin junctions and their role as epicenters of differentiation-specific actin regulation in the developing lens Developmental Biology 2011 349:363-377 DOI:10.1016/j.ydbio.2010.10.009 PMID:20969840 PMCID:PMC3018542
- Moyer, J. D., Nowak, R. B., Kim, N. E., Larkin, S. K., Peters, L. L., Hartwig, J., Kuypers, F. A., Fowler, V. M. Tropomodulin 1-null mice have a mild spherocytic elliptocytosis with appearance of tropomodulin 3 in red blood cells and disruption of the membrane skeleton Blood 2010 116:2590-2599 DOI:10.1182/blood-2010-02-268458 PMID:20585041 PMCID:PMC2953891
- Gokhin, D. S., Lewis, R. A., McKeown, C. R., Nowak, R. B., Kim, N. E., Littlefield, R. S., Lieber, R. L., Fowler, V. M. Tropomodulin isoforms regulate thin filament pointed-end capping and skeletal muscle physiology Journal of Cell Biology 2010 189:95-109 DOI:10.1083/jcb.201001125 PMID:20368620 PMCID:PMC2854367
- Nowak, R. B., Fischer, R. S., Zoltoski, R. K., Kuszak, J. R., Fowler, V. M. Tropomodulin1 is required for membrane skeleton organization and hexagonal geometry of fiber cells in the mouse lens Journal of Cell Biology 2009 186:915-928 DOI:10.1083/jcb.200905065 PMID:19752024 PMCID:PMC2753162
- McKeown, C. R., Nowak, R. B., Moyer, J., Sussman, M. A., Fowler, V. M. Tropomodulin1 is required in the heart but not the yolk sac for mouse embryonic development Circulation Research 2008 103:1241-1248 DOI:10.1161/circresaha.108.178749 PMID:18927466 PMCID:PMC2744601