recent publications

• academic article

  • Sui, Z., Nowak, R. B., Sanada, C., Halene, S., Krause, D. S., Fowler, V. M. Regulation of actin polymerization by tropomodulin-3 controls megakaryocyte actin organization and platelet biogenesis Blood  2015 126:520-530  DOI:10.1182/blood-2014-09-601484  PMID:25964668  PMCID:PMC4513252
  • Cheng, C., Nowak, R. B., Gao, J., Sun, X., Biswas, S. K., Lo, W. K., Mathias, R. T., Fowler, V. M. Lens ion homeostasis relies on the assembly and/or stability of large connexin 46 gap junction plaques on the broad sides of differentiating fiber cells American Journal of Physiology-Cell Physiology  2015 308:C835-C847  DOI:10.1152/ajpcell.00372.2014  PMID:25740157  PMCID:PMC4436989
  • Gokhin, D. S., Nowak, R. B., Khoory, J. A., de la Piedra, A., Ghiran, I. C., Fowler, V. M. Dynamic actin filaments control the mechanical behavior of the human red blood cell membrane Molecular Biology of the Cell  2015 26:1699-1710  DOI:10.1091/mbc.E14-12-1583  PMID:25717184  PMCID:PMC4436781
  • McKeown, C. R., Nowak, R. B., Gokhin, D. S., Fowler, V. M. Tropomyosin is required for cardiac morphogenesis, myofibril assembly, and formation of adherens junctions in the developing mouse embryo Developmental Dynamics  2014 243:800-817  DOI:10.1002/dvdy.24115  PMID:24500875  PMCID:PMC4031292
  • Sui, Z., Nowak, R. B., Bacconi, A., Kim, N. E., Liu, H., Li, J., Wickrema, A., An, X. L., Fowler, V. M. Tropomodulin3-null mice are embryonic lethal with anemia due to impaired erythroid terminal differentiation in the fetal liver Blood  2014 123:758-767  DOI:10.1182/blood-2013-03-492710  PMID:24159174  PMCID:PMC3907761
  • Gokhin, D. S., Nowak, R. B., Kim, N. E., Arnett, E. E., Chen, A. C., Sah, R. L., Clark, J. I., Fowler, V. M. Tmod1 and CP49 synergize to control the fiber cell geometry, transparency, and mechanical stiffness of the mouse lens PLoS One  2012 7:e48734  DOI:10.1371/journal.pone.0048734  PMID:23144950  PMCID:PMC3492431
  • Nowak, R. B., Fowler, V. M. Tropomodulin 1 constrains fiber cell geometry during elongation and maturation in the lens cortex Journal of Histochemistry and Cytochemistry  2012 60:414-427  DOI:10.1369/0022155412440881  PMID:22473940  PMCID:PMC3393074
  • Yamashiro, S., Gokhin, D. S., Kimura, S., Nowak, R. B., Fowler, V. M. Tropomodulins: pointed-end capping proteins that regulate actin filament architecture in diverse cell types Cytoskeleton  2012 69:337-370  DOI:10.1002/cm.21031  PMID:22488942  PMCID:PMC3444156
  • Leonard, M., Zhang, L. P., Zhai, N., Cader, A., Chan, Y., Nowak, R. B., Fowler, V. M., Menko, A. S. Modulation of N-cadherin junctions and their role as epicenters of differentiation-specific actin regulation in the developing lens Developmental Biology  2011 349:363-377  DOI:10.1016/j.ydbio.2010.10.009  PMID:20969840  PMCID:PMC3018542
  • Moyer, J. D., Nowak, R. B., Kim, N. E., Larkin, S. K., Peters, L. L., Hartwig, J., Kuypers, F. A., Fowler, V. M. Tropomodulin 1-null mice have a mild spherocytic elliptocytosis with appearance of tropomodulin 3 in red blood cells and disruption of the membrane skeleton Blood  2010 116:2590-2599  DOI:10.1182/blood-2010-02-268458  PMID:20585041  PMCID:PMC2953891
  • Gokhin, D. S., Lewis, R. A., McKeown, C. R., Nowak, R. B., Kim, N. E., Littlefield, R. S., Lieber, R. L., Fowler, V. M. Tropomodulin isoforms regulate thin filament pointed-end capping and skeletal muscle physiology Journal of Cell Biology  2010 189:95-109  DOI:10.1083/jcb.201001125  PMID:20368620  PMCID:PMC2854367
  • Nowak, R. B., Fischer, R. S., Zoltoski, R. K., Kuszak, J. R., Fowler, V. M. Tropomodulin1 is required for membrane skeleton organization and hexagonal geometry of fiber cells in the mouse lens Journal of Cell Biology  2009 186:915-928  DOI:10.1083/jcb.200905065  PMID:19752024  PMCID:PMC2753162
  • McKeown, C. R., Nowak, R. B., Moyer, J., Sussman, M. A., Fowler, V. M. Tropomodulin1 is required in the heart but not the yolk sac for mouse embryonic development Circulation Research  2008 103:1241-1248  DOI:10.1161/circresaha.108.178749  PMID:18927466  PMCID:PMC2744601