recent publications
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academic article
- Gao, J. M., Bosco, D. A., Powers, E. T., Kelly, J. W. Localized thermodynamic coupling between hydrogen bonding and microenvironment polarity substantially stabilizes proteins Nature Structural & Molecular Biology 2009 16:684-690 DOI:10.1038/nsmb.1610 PMID:19525973 PMCID:PMC2754385
- Bieschke, J., Zhang, Q. H., Bosco, D. A., Lerner, R. A., Powers, E. T., Wentworth, P., Kelly, J. W. Small molecule oxidation products trigger disease-associated protein misfolding Accounts of Chemical Research 2006 39:611-619 DOI:10.1021/ar0500766 PMID:16981677
- Bosco, D. A., Fowler, D. M., Zhang, Q. H., Nieva, J., Powers, E. T., Wentworth, P., Lerner, R. A., Kelly, J. W. Elevated levels of oxidized cholesterol metabolites in lewy body disease brains accelerate alpha-synuclein fibrilization Nature Chemical Biology 2006 2:249-253 DOI:10.1038/nchembio782 PMID:16565714