recent publications

• academic article

  • Hsu, C., Boysen, M., Gritton, L. D., Frosst, P. D., Nemerow, G. R., Von Seggern, D. J. In vitro dendritic cell infection by pseudotyped adenoviral vectors does not correlate with their in vivo immunogenicity Virology  2005 332:1-7  DOI:10.1016/j.virol.2004.11.014  PMID:15661134
  • Wu, E., Trauger, S. A., Pache, L., Mullen, T. M., Von Seggern, D. J., Siuzdak, G., Nemerow, G. R. Membrane cofactor protein is a receptor for adenoviruses associated with epidemic keratoconjunctivitis Journal of Virology  2004 78:3897-3905  DOI:10.1128/jvi.78.8.3897-3905.2004  PMID:15047806
  • Wu, E., Pache, L., Von Seggern, D. J., Mullen, T. M., Mikyas, Y., Stewart, P. L., Nemerow, G. R. Flexibility of the adenovirus fiber is required for efficient receptor interaction Journal of Virology  2003 77:7225-7235  DOI:10.1128/jvi.77.13.7225-7235.2003  PMID:12805421
  • Von Seggern, D. J., Aguilar, E., Kinder, K., Fleck, S. K., Armas, J. C. G., Stevenson, S. C., Ghazal, P., Nemerow, G. R., Friedlander, M. In vivo transduction of photoreceptors or ciliary body by intravitreal injection of pseudotyped adenoviral vectors Molecular Therapy  2003 7:27-34  DOI:10.1016/s1525-0016(02)00030-8  PMID:12573615
  • Nicklin, S. A., Dishart, K. L., Buening, H., Reynolds, P. N., Hallek, M., Nemerow, G. R., Von Seggern, D. J., Baker, A. H. Transductional and transcriptional targeting of cancer cells using genetically engineered viral vectors Cancer Letters  2003 201:165-173  DOI:10.1016/j.canlet.2003.07.003  PMID:14607330
  • Wu, E., Fernandez, J., Fleck, S. K., Von Seggern, D. J., Huang, S., Nemerow, G. R. A 50-kDa membrane protein mediates sialic acid-independent binding and infection of conjunctival cells by adenovirus type 37 Virology  2001 279:78-89  DOI:10.1006/viro.2000.0703  PMID:11145891
  • Nicklin, S. A., Von Seggern, D. J., Work, L. M., Pek, D. C. K., Dominiczak, A. F., Nemerow, G. R., Baker, A. H. Ablating adenovirus type 5 fiber-car binding and hi loop insertion of the sigyplp peptide generate an endothelial cell-selective adenovirus Molecular Therapy  2001 4:534-542  DOI:10.1006/mthe.2001.0489  PMID:11735337
  • Jakubczak, J. L., Rollence, M. L., Stewart, D. A., Jafari, J. D., Von Seggern, D. J., Nemerow, G. R., Stevenson, S. C., Hallenbeck, P. L. Adenovirus type 5 viral particles pseudotyped with mutagenized fiber proteins show diminished infectivity of coxsackie b-adenovirus receptor-bearing cells Journal of Virology  2001 75:2972-2981  DOI:10.1128/jvi.75.6.2972-2981.2001  PMID:11222722
  • Chiu, C. Y., Wu, E., Brown, S. L., Von Seggern, D. J., Nemerow, G. R., Stewart, P. L. Structural analysis of a fiber-pseudotyped adenovirus with ocular tropism suggests differential modes of cell receptor interactions Journal of Virology  2001 75:5375-5380  DOI:10.1128/jvi.75.11.5375-5380.2001  PMID:11333920
  • Von Seggern, D. J., Huang, S., Fleck, S. K., Stevenson, S. C., Nemerow, G. R. Adenovirus vector pseudotyping in fiber-expressing cell lines: Improved transduction of epstein-barr virus-transformed b cells Journal of Virology  2000 74:354-362  PMID:10590124  PMCID:PMC111546
  • Li, E., Brown, S. L., Von Seggern, D. J., Brown, G. B., Nemerow, G. R. Signaling antibodies complexed with adenovirus circumvent car and integrin interactions and improve gene delivery Gene Therapy  2000 7:1593-1599  DOI:10.1038/sj.gt.3301271  PMID:11021598
  • Von Seggern, D. J., Kehler, J., Endo, R. I., Nemerow, G. R. Complementation of a fibre mutant adenovirus by packaging cell lines stably expressing the adenovirus type 5 fibre protein Journal of General Virology  1998 79:1461-1468  PMID:9634089