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The kinetic mechanism of the hairpin ribozyme in vivo: Influence of RNA helix stability on intracellular cleavage kinetics

Academic Article
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Overview

authors

  • Donahue, C. P.
  • Yadava, R. S.
  • Nesbitt, S. M.
  • Fedor, Martha

publication date

  • January 2000

journal

  • Journal of Molecular Biology  Journal

subject areas

  • Base Pairing
  • Base Sequence
  • DNA Primers
  • Hydrolysis
  • Kinetics
  • Molecular Sequence Data
  • Nucleic Acid Conformation
  • Osmolar Concentration
  • RNA, Catalytic
  • Thermodynamics
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Research

keywords

  • RNA catalysis
  • enzyme mechanism
  • hairpin ribozyme
  • intracellular kinetics
  • mRNA degradation
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Identity

International Standard Serial Number (ISSN)

  • 0022-2836

Digital Object Identifier (DOI)

  • 10.1006/jmbi.1999.3380

PubMed ID

  • 10623557
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Additional Document Info

start page

  • 693

end page

  • 707

volume

  • 295

issue

  • 3

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