recent publications
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academic article
- Li, Q., Zeng, M., Duan, L., Voss, J. E., Smith, A. J., Pambuccian, S., Shang, L., Wietgrefe, S., Southern, P. J., Reilly, C. S., Skinner, P. J., Zupancic, M. L., et al. Live simian immunodeficiency virus vaccine correlate of protection: local antibody production and concentration on the path of virus entry Journal of Immunology 2014 193:3113-3125 DOI:10.4049/jimmunol.1400820 PMID:25135832 PMCID:PMC4157131
- Madani, N., Princiotto, A. M., Schon, A., LaLonde, J., Feng, Y., Freire, E., Park, J., Courter, J. R., Jones, D. M., Robinson, J., Liao, H. X., Moody, M. A., et al. CD4-mimetic small molecules sensitize human immunodeficiency virus to vaccine-elicited antibodies Journal of Virology 2014 88:6542-6555 DOI:10.1128/jvi.00540-14 PMID:24696475 PMCID:PMC4054336
- Robinson, J., Smith, A., Sturchler, E., Tabrizifard, S., Kamenecka, T., McDonald, P. Development of a high-throughput screening-compatible cell-based functional assay to identify small molecule probes of the galanin 3 receptor (GalR3) Assay and Drug Development Technologies 2013 11:468-477 DOI:10.1089/adt.2013.526 PMID:24116939 PMCID:PMC3804082
- Chakrabarti, B. K., Pancera, M., Phogat, S., O'Dell, S., McKee, K., Guenaga, J., Robinson, J., Mascola, J., Wyatt, R. T. Hiv type 1 env precursor cleavage state affects recognition by both neutralizing and nonneutralizing gp41 antibodies AIDS Research and Human Retroviruses 2011 27:877-887 DOI:10.1089/aid.2010.0281 PMID:21158699 PMCID:PMC3159124
- Peters, P. J., Duenas-Decamp, M. J., Sullivan, W. M., Brown, R., Ankghuambom, C., Luzuriaga, K., Robinson, J., Burton, D. R., Bell, J., Simmonds, P., Ball, J., Clapham, P. R. Variation in hiv-i r5 macrophage-tropism correlates with sensitivity to reagents that block envelope: Cd4 interactions but not with sensitivity to other entry inhibitors Retrovirology 2008 5:5 DOI:10.1186/1742-4690-5-5 PMID:18205925 PMCID:PMC2268948
- Huang, C. C., Lam, S. N., Acharya, P., Tang, M., Xiang, S. H., Hussan, S. S. U., Stanfield, R. L., Robinson, J., Sodroski, J., Wilson, I. A., Wyatt, R., Bewley, C. A., et al. Structures of the ccr5 n terminus and of a tyrosine-sulfated antibody with hiv-1 gp120 and cd4 Science 2007 317:1930-1934 DOI:10.1126/science.1145373 PMID:17901336 PMCID:PMC2278242
- Xiang, S. H., Farzan, M., Si, Z. H., Madani, N., Wang, L., Rosenberg, E., Robinson, J., Sodroski, J. Functional mimicry of a human immunodeficiency virus type 1 coreceptor by a neutralizing monoclonal antibody Journal of Virology 2005 79:6068-6077 DOI:10.1128/jvi.79.10.6068-6077.2005 PMID:15857992
- Huang, C. C., Stricher, F., Martin, L., Decker, J. M., Majeed, S., Barthe, P., Hendrickson, W. A., Robinson, J., Roumestand, C., Sodroski, J., Wyatt, R., Shaw, G. M., et al. Scorpion-toxin mimics of cd4 in complex with human immunodeficiency virus gp120: Crystal structures, molecular mimicry, and neutralization breadth Structure 2005 13:755-768 DOI:10.1016/j.str.2005.03.006 PMID:15893666
- Huang, C. C., Venturi, M., Majeed, S., Moore, M. J., Phogat, S., Zhang, M. Y., Dimitrov, D. S., Hendrickson, W. A., Robinson, J., Sodroski, J., Wyatt, R., Choe, H., et al. Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120 Proceedings of the National Academy of Sciences of the United States of America 2004 101:2706-2711 DOI:10.1073/pnas.0308527100 PMID:14981267 PMCID:PMC365685
- Labrijn, A. F., Poignard, P., Raja, A., Zwick, M. B., Delgado, K., Franti, M., Binley, J., Vivona, V., Grundner, C., Huang, C. C., Venturi, M., Petropoulos, C. J., et al. Access of antibody molecules to the conserved coreceptor binding site on glycoprotein gpl120 is sterically restricted on primary human immunodeficiency virus type 1 Journal of Virology 2003 77:10557-10565 DOI:10.1128/jvi.77.19.10557-10565.2003 PMID:12970440
- Kwong, P. D., Doyle, M. L., Casper, D. J., Cicala, C., Leavitt, S. A., Majeed, S., Steenbeke, T. D., Venturi, M., Chaiken, I., Fung, M., Katinger, H., Parren, Pwlh, et al. HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sites Nature 2002 420:678-682 DOI:10.1038/nature01188 PMID:12478295
- Moulard, M., Phogat, S. K., Shu, Y., Labrijn, A. F., Xiao, X. D., Binley, J. M., Zhang, M. Y., Sidorov, I. A., Broder, C. C., Robinson, J., Parren, Pwhi, Burton, D. R., et al. Broadly cross-reactive hiv-1-neutralizing human monoclonal fab selected for binding to gp120-cd4-ccr5 complexes Proceedings of the National Academy of Sciences of the United States of America 2002 99:6913-6918 DOI:10.1073/pnas.102562599 PMID:11997472 PMCID:PMC124503
- Kwong, P. D., Wyatt, R., Majeed, S., Robinson, J., Sweet, R. W., Sodroski, J., Hendrickson, W. A. Structures of hiv-1 gp120 envelope glycoproteins from laboratory-adapted and primary isolates Structure 2000 8:1329-1339 DOI:10.1016/s0969-2126(00)00547-5 PMID:11188697
- Farzan, M., Vasilieva, N., Schnitzler, C. E., Chung, S., Robinson, J., Gerard, N. P., Gerard, C., Choe, H., Sodroski, J. A tyrosine-sulfated peptide based on the N terminus of CCR5 interacts with a CD4-enhanced epitope of the HIV-1 gp120 envelope glycoprotein and inhibits HIV-1 entry Journal of Biological Chemistry 2000 275:33516-33521 DOI:10.1074/jbc.M007228200 PMID:10938094
- Kwong, P. D., Wyatt, R., Desjardins, E., Robinson, J., Culp, J. S., Hellmig, B. D., Sweet, R. W., Sodroski, J., Hendrickson, W. A. Probability analysis of variational crystallization and its application to gp120, the exterior envelope glycoprotein of type 1 human immunodeficiency virus (hiv-1) Journal of Biological Chemistry 1999 274:4115-4123 DOI:10.1074/jbc.274.7.4115 PMID:9933605
- Kwong, P. D., Wyatt, R., Robinson, J., Sweet, R. W., Sodroski, J., Hendrickson, W. A. Structure of an hiv gp120 envelope glycoprotein in complex with the cd4 receptor and a neutralizing human antibody Nature 1998 393:648-659 PMID:9641677
- Cao, J., Sullivan, N., Desjardin, E., Parolin, C., Robinson, J., Wyatt, R., Sodroski, J. Replication and neutralization of human immunodeficiency virus type 1 lacking the v1 and v2 variable loops of the gp120 envelope glycoprotein Journal of Virology 1997 71:9808-9812 PMID:9371651 PMCID:PMC230295
- Martin, K. A., Wyatt, R., Farzan, M., Choe, H., Marcon, L., Desjardins, E., Robinson, J., Sodroski, J., Gerard, C., Gerard, N. P. CD4-independent binding of SIV gp120 to rhesus CCR5 Science 1997 278:1470-1473 DOI:10.1126/science.278.5342.1470 PMID:9367961
- Baba, T. W., Sodroski, J., ZollaPazner, S., Gorny, M. K., Robinson, J., Posner, M. R., Katinger, H., Barbas, C. F., Burton, D. R., Chou, T. C., Ruprecht, R. M., Li, A. Synergistic neutralization of a chimeric SIV/HIV type 1 virus with combinations of human anti-HIV type 1 envelope monoclonal antibodies or hyperimmune globulins AIDS Research and Human Retroviruses 1997 13:647-656 DOI:10.1089/aid.1997.13.647 PMID:9168233
- Wyatt, R., Moore, J., Accola, M., Desjardin, E., Robinson, J., Sodroski, J. Involvement of the v1/v2 variable loop structure in the exposure of human-immunodeficiency-virus type-1 gp120 epitopes induced by receptor-binding Journal of Virology 1995 69:5723-5733 PMID:7543586 PMCID:PMC189432
- Moore, J. P., Cao, Y. Z., Qing, L., Sattentau, Q. J., Pyati, J., Koduri, R., Robinson, J., Barbas, C. F., Burton, D. R., Ho, D. D. Primary isolates of human-immunodeficiency-virus type-1 are relatively resistant to neutralization by monoclonal-antibodies to gp120, and their neutralization is not predicted by studies with monomeric gp120 Journal of Virology 1995 69:101-109 PMID:7527081 PMCID:PMC188553
- Moore, J. P., Cao, Y. Z., Conley, A. J., Wyatt, R., Robinson, J., Gorny, M. K., Zollapazner, S., Ho, D. D., Koup, R. A. Studies with monoclonal antibodies to the V3 region of HIV-1 gp120 reveal limitations to the utility of solid-phase peptide binding assays Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology 1994 7:332-339 PMID:7510807
- Wyatt, R., Sullivan, N., Thali, M., Repke, H., Ho, D., Robinson, J., Posner, M., Sodroski, J. Functional and immunological characterization of human-immunodeficiency-virus type-1 envelope glycoproteins containing deletions of the major variable regions Journal of Virology 1993 67:4557-4565 PMID:8331723 PMCID:PMC237840
- Wyatt, R., Thali, M., Tilley, S., Pinter, A., Posner, M., Ho, D., Robinson, J., Sodroski, J. Relationship of the human-immunodeficiency-virus type-1 gp120 3rd variable loop to a component of the cd4 binding-site in the 4th conserved region Journal of Virology 1992 66:6997-7004 PMID:1279195 PMCID:PMC240347
- Tan, E. M., Robinson, J., Robitaille, P. Studies on antibodies to histones by immunofluorescence Scandinavian Journal of Immunology 1976 5:811-818 DOI:10.1111/j.1365-3083.1976.tb03030.x PMID:62391