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Academic Article
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Overview

authors

  • Saurin, A. J.
  • Borden, K. L. B.
  • Boddy, Michael
  • Freemont, P. S.

publication date

  • June 1996

journal

  • Trends in Biochemical Sciences  Journal

abstract

  • The RING finger is a zinc-binding domain that is found in proteins from plants to humans, but whose function remains largely enigmatic. The domain itself is distinct from other zinc-finger motifs in terms of sequence homology, zinc-ligation scheme and three-dimensional structure. It appears that the RING is involved in mediating protein-protein interactions and in some cases multi-protein complexes, which might depend on the presence of other proteins and/or domains.

subject areas

  • Binding Sites
  • Cysteine
  • DNA-Binding Proteins
  • Major Histocompatibility Complex
  • Metalloproteins
  • Microbodies
  • Models, Molecular
  • Protein Structure, Tertiary
  • Proteins
  • Signal Transduction
  • Zinc
  • Zinc Fingers
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Identity

International Standard Serial Number (ISSN)

  • 0968-0004

Digital Object Identifier (DOI)

  • 10.1016/s0968-0004(96)80017-x

PubMed ID

  • 8744354
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Additional Document Info

start page

  • 208

end page

  • 214

volume

  • 21

issue

  • 6

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