recent publications

• academic article

  • Sugama, S., Takenouchi, T., Fujita, M., Kitani, H., Conti, B., Hashimoto, M. Corticosteroids limit microglial activation occurring during acute stress Neuroscience  2013 232:13-20  DOI:10.1016/j.neuroscience.2012.12.012  PMID:23262242
  • Morrison, B. E., Marcondes, M. C. G., Nomura, D. K., Sanchez-Alavez, M., Sanchez-Gonzalez, A., Saar, I., Kim, K. S., Bartfai, T., Maher, P., Sugama, S., Conti, B. Cutting edge: IL-13Rα1 expression in dopaminergic neurons contributes to their oxidative stress-mediated loss following chronic peripheral treatment with lipopolysaccharide Journal of Immunology  2012 189:5498-5502  DOI:10.4049/jimmunol.1102150  PMID:23169588  PMCID:PMC3545403
  • Takenouchi, T., Iwamaru, Y., Sugama, S., Tsukimoto, M., Fujita, M., Sekigawa, A., Sekiyama, K., Sato, M., Kojima, S., Conti, B., Hashimoto, M., Kitani, H. The activation of P2X7 receptor induces cathepsin D-dependent production of a 20-kDa form of IL-1 beta under acidic extracellular pH in LPS-primed microglial cells Journal of Neurochemistry  2011 117:712-723  DOI:10.1111/j.1471-4159.2011.07240.x  PMID:21395581
  • Alboni, S., Cervia, D., Sugama, S., Conti, B. Interleukin 18 in the CNS Journal of Neuroinflammation  2010 7:9  DOI:10.1186/1742-2094-7-9  PMID:20113500  PMCID:PMC2830964
  • Alboni, S., Cervia, D., Ross, B., Montanari, C., Gonzalez, A. S., Sanchez-Alavez, M., Marcondes, M. C. G., De Vries, D., Sugama, S., Brunello, N., Blom, J., Tascedda, F., et al. Mapping of the full length and the truncated interleukin-18 receptor alpha in the mouse brain Journal of Neuroimmunology  2009 214:43-54  DOI:10.1016/j.jneuroim.2009.06.016  PMID:19640592  PMCID:PMC2745497
  • Sugama, S., Takenouchi, T., Fujita, M., Conti, B., Hashimoto, M. Differential microglial activation between acute stress and lipopolysaccharide treatment Journal of Neuroimmunology  2009 207:24-31  DOI:10.1016/j.jneuroim.2008.11.007  PMID:19111355
  • Sugama, S., Conti, B. Interleukin-18 and stress Brain Research Reviews  2008 58:85-95  DOI:10.1016/j.brainresrev.2007.11.003  PMID:18295340
  • Zorriila, E. P., Sanchez-Alavez, M., Sugama, S., Brennan, M., Fernandez, R., Bartfai, T., Conti, B. Interleukin-18 controls energy homeostasis by suppressing appetite and feed efficiency Proceedings of the National Academy of Sciences of the United States of America  2007 104:11097-11102  DOI:10.1073/pnas.0611523104  PMID:17578927  PMCID:PMC1904154
  • Sugama, S., Fujita, M., Hashimoto, M., Conti, B. Stress induced morphological microglial activation in the rodent brain: Involvement of interleukin-18 Neuroscience  2007 146:1388-1399  DOI:10.1016/j.neuroscience.2007.02.043  PMID:17433555
  • Wang, N., Sugama, S., Conti, B., Teramoto, A., Shibasaki, T. Interleukin-18 mRNA expression in the rat pituitary gland Journal of Neuroimmunology  2006 173:117-125  DOI:10.1016/j.jneuroim.2005.12.009  PMID:16460811
  • Sugama, S., Wang, N., Shimokawa, N., Koibuchi, N., Fujita, M., Hashimoto, M., Dhabhar, F. S., Conti, B. The adrenal gland is a source of stress-induced circulating IL-18 Journal of Neuroimmunology  2006 172:59-65  DOI:10.1016/j.jneuroim.2005.11.001  PMID:16359733
  • Conti, B., Sugama, S., Lucero, J., Winsky-Sommerer, R., Wirz, S. A., Maher, P., Andrews, Z., Barr, A. M., Morale, M. C., Paneda, C., Pemberton, J., Gaidarova, S., et al. Uncoupling protein 2 protects dopaminergic neurons from acute 1,2,3,6-methyl-phenyl-tetrahydropyridine toxicity Journal of Neurochemistry  2005 93:493-501  DOI:10.1111/j.1471-4159.2005.03052.x  PMID:15816872
  • Solforosi, L., Criado, J. R., McGavern, D. B., Wirz, S., Sanchez-Alavez, M., Sugama, S., DeGiorgio, L. A., Volpe, B. T., Wiseman, E., Abalos, G., Masliah, E., Gilden, D., et al. Cross-linking cellular prion protein triggers neuronal apoptosis in vivo Science  2004 303:1514-1516  DOI:10.1126/science.1094273  PMID:14752167
  • Sugama, S., Wirz, S. A., Barr, A. M., Conti, B., Bartfai, T., Shibasaki, T. Interleukin-18 null mice show diminished microglial activation and reduced dopaminergic neuron loss following acute 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine treatment Neuroscience  2004 128:451-458  DOI:10.1016/j.neuroscience.2004.07.020  PMID:15350655
  • Sugama, S., Cho, B. P., Baker, H., Joh, T. H., Lucero, J., Conti, B. Neurons of the superior nucleus of the medial habenula and ependymal cells express IL-18 in rat CNS Brain Research  2002 958:1-9  DOI:10.1016/s0006-8993(02)03363-2  PMID:12468024
  • Sugama, S., Kim, Y. S., Baker, H., Tinti, C., Kim, H., Joh, T. H., Conti, B. Tissue-specific expression of rat IL-18 gene and response to adrenocorticotropic hormone treatment Journal of Immunology  2000 165:6287-6292  PMID:11086064
  • Conti, B., Sugama, S., Kim, Y., Tinti, C., Kim, H., Baker, H., Volpe, B., Attardi, B., Joh, T. Modulation of IL-18 production in the adrenal cortex following acute ACTH or chronic corticosterone treatment Neuroimmunomodulation  2000 8:1-7  DOI:10.1159/000026445  PMID:10859481