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Carbohydrate mimetics: a new strategy for tackling the problem of carbohydrate-mediated biological recognition

Academic Article
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Overview

authors

  • Sears, Pamela
  • Wong, Chi-Huey

publication date

  • 1999

journal

  • Angewandte Chemie-International Edition  Journal

abstract

  • Useful strategies for the design of molecules to mimic carbohydrates have been developed over the past few years. Mimics of the target may contain new functional groups, a new scaffold, or both (in the schematic representation the natural ligand is shown on the left and the modified version on the right). Many examples of successful carbohydrate mimetics that interfere with sugar-protein and sugar-nucleic acid interactions are known.
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Research

keywords

  • carbohydrate mimetics
  • carbohydrates
  • sialic acids
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Identity

International Standard Serial Number (ISSN)

  • 1433-7851

Digital Object Identifier (DOI)

  • 10.1002/(SICI)1521-3773(19990816)38:16<2300::AID-ANIE2300>3.0.CO;2-6

PubMed ID

  • 10458780
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Additional Document Info

start page

  • 2300

end page

  • 2324

volume

  • 38

issue

  • 16

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