related to degree

• Johnson, Jeffrey R, Ph.D. in Biochemistry, Scripps Research 2002 - 2007

authors

• Johnson, Jeffrey R
• Florens, L.
• Carucci, D. J.
• Yates III, John

publication date

• March 2004

journal

• Journal of Proteome Research  Journal

abstract

• The recent completion of human, Anopheles gambiae, and Plasmodium falciparum genomes relevant to the study of human malaria allows the application of modern proteomic technologies to complement previously implemented conventional approaches. Proteomic analysis has been employed to elucidate global protein expression profiles, subcellular localization of gene products, and host-pathogen interactions that are central to disease pathogenesis and treatment. The high-throughput nature of these techniques is in accord with the pace of drug and vaccine development that have the potential to directly reduce the morbidity and mortality of disease.

subject areas

• Animals
• Anopheles
• Chromatography, Liquid
• Electrophoresis, Gel, Two-Dimensional
• Genome, Human
• Humans
• Malaria
• Mass Spectrometry
• Peptides
• Plasmodium falciparum
• Proteome
• Proteomics

keywords

• Plasmodium falciparum
• malaria
• mass spectrometry
• proteomics

International Standard Serial Number (ISSN)

• 1535-3893

Digital Object Identifier (DOI)

• 10.1021/pr0340781

PubMed ID

• 15113107

start page

• 296

end page

• 306

volume

• 3

issue

• 2