recent publications
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academic article
- Mosnier, L. O., Buijtenhuijs, P., Marx, P. F., Meijers, J. C. M., Bouma, B. N. Identification of thrombin activatable fibrinolysis inhibitor (tafi) in human platelets Blood 2003 101:4844-4846 DOI:10.1182/blood-2002-09-2944 PMID:12595308
- Reijerkerk, A., Mosnier, L. O., Kranenburg, O., Bouma, B. N., Carmeliet, P., Drixler, T., Meijers, J. C. M., Voest, E. E., Gebbink, Mfbg Amyloid endostatin induces endothelial cell detachment by stimulation of the plasminogen activation system Molecular Cancer Research 2003 1:561-568 PMID:12805403
- Marx, P. F., Dawson, P. E., Bouma, B. N., Meijers, J. C. M. Plasmin-mediated activation and inactivation of thrombin-activatable fibrinolysis inhibitor Biochemistry 2002 41:6688-6696 DOI:10.1021/bi015982e PMID:12022872
- Lisman, T., Mosnier, L. O., Lambert, T., Mauser-Bunschoten, E. P., Meijers, J. C. M., Nieuwenhuis, H. K., de Groot, P. G. Inhibition of fibrinolysis by recombinant factor viia in plasma from patients with severe hemophilia a Blood 2002 99:175-179 DOI:10.1182/blood.V99.1.175 PMID:11756168
- Mosnier, L. O., Elisen, Mglm, Bouma, B. N., Meijers, J. C. M. Protein c inhibitor regulates the thrombin-thrombomodulin complex in the up- and down regulation of tafi activation Thrombosis and Haemostasis 2001 86:1057-1064 PMID:11686324
- Mosnier, L. O., Lisman, T., van den Berg, H. M., Nieuwenhuis, H. K., Meijers, J. C. M., Bouma, B. N. The defective down regulation of fibrinolysis in haemophilia a can be restored by increasing the tafi plasma concentration Thrombosis and Haemostasis 2001 86:1035-1039 PMID:11686321
- Mosnier, L. O., Meijers, J. C. M., Bouma, B. N. The role of protein s in the activation of thrombin activatable fibrinolysis inhibitor (tafi) and regulation of fibrinolysis Thrombosis and Haemostasis 2001 86:1040-1046 PMID:11686322
- Lisman, T., Leebeek, F. W. G., Mosnier, L. O., Bouma, B. N., Meijers, J. C. M., Janssen, H. L. A., Nieuwenhuis, H. K., De Groot, P. G. Thrombin-activatable fibrinolysis inhibitor deficiency in cirrhosis is not associated with increased plasma fibrinolysis Gastroenterology 2001 121:131-139 DOI:10.1053/gast.2001.25481 PMID:11438502
- Bouma, B. N., Marx, P. F., Mosnier, L. O., Meijers, J. C. M. Thrombin-activatable fibrinolysis inhibitor (tafi, plasma procarboxypeptidase b, procarboxypeptidase r, procarboxypeptidase u) Thrombosis Research 2001 101:329-354 DOI:10.1016/s0049-3848(00)00411-4 PMID:11297751
- Mosnier, L. O., Meijers, J. C. M., Bouma, B. N. Regulation of fibrinolysis in plasma by tafi and protein c is dependent on the concentration of thrombomodulin Thrombosis and Haemostasis 2001 85:5-11 PMID:11204587
- Marx, P. F., Hackeng, T. M., Dawson, P. E., Griffin, J. H., Meijers, J. C. M., Bouma, B. N. Inactivation of active thrombin-activable fibrinolysis inhibitor takes place by a process that involves conformational instability rather than proteolytic cleavage Journal of Biological Chemistry 2000 275:12410-12415 DOI:10.1074/jbc.275.17.12410 PMID:10777524
- Meijers, J. C. M., Oudijk, E. J. D., Mosnier, L. O., Bos, R., Bouma, B. N., Nieuwenhuis, H. K., Fijnheer, R. Reduced activity of tafi (thrombin-activatable fibrinolysis inhibitor) in acute promyelocytic leukaemia British Journal of Haematology 2000 108:518-523 DOI:10.1046/j.1365-2141.2000.01890.x PMID:10759708
- Bouma, B. N., Mosnier, L. O., Meijers, J. C. M., Griffin, J. H. Factor XI dependent and independent activation of thrombin activatable fibrinolysis inhibitor (TAFI) in plasma associated with clot formation Thrombosis and Haemostasis 1999 82:1703-1708 PMID:10613658
- Mosnier, L. O., von dem Borne, P. A. K., Meijers, J. C. M., Bouma, B. N. Plasma tafi levels influence the clot lysis time in healthy individuals in the presence of an intact intrinsic pathway of coagulation Thrombosis and Haemostasis 1998 80:829-835 PMID:9843179
- Minnema, M. C., Friederich, P. W., Levi, M., von dem Borne, P. A. K., Mosnier, L. O., Meijers, J. C. M., Biemond, B. J., Hack, C. E., Bouma, B. N., ten Cate, H. Enhancement of rabbit jugular vein thrombolysis by neutralization of factor xi - in vivo evidence for a role of factor xi as an anti-fibrinolytic factor Journal of Clinical Investigation 1998 101:10-14 DOI:10.1172/jci781 PMID:9421460
- vondemBorne, P. A. K., Mosnier, L. O., Tans, G., Meijers, J. C. M., Bouma, B. N. Factor xi activation by meizothrombin: Stimulation by phospholipid vesicles containing both phosphatidylserine and phosphatidylethanolamine Thrombosis and Haemostasis 1997 78:834-839 PMID:9268180