recent publications

• academic article

  • Mosnier, L. O., Buijtenhuijs, P., Marx, P. F., Meijers, J. C. M., Bouma, B. N. Identification of thrombin activatable fibrinolysis inhibitor (tafi) in human platelets Blood  2003 101:4844-4846  DOI:10.1182/blood-2002-09-2944  PMID:12595308
  • Reijerkerk, A., Mosnier, L. O., Kranenburg, O., Bouma, B. N., Carmeliet, P., Drixler, T., Meijers, J. C. M., Voest, E. E., Gebbink, Mfbg Amyloid endostatin induces endothelial cell detachment by stimulation of the plasminogen activation system Molecular Cancer Research  2003 1:561-568  PMID:12805403
  • Marx, P. F., Dawson, P. E., Bouma, B. N., Meijers, J. C. M. Plasmin-mediated activation and inactivation of thrombin-activatable fibrinolysis inhibitor Biochemistry  2002 41:6688-6696  DOI:10.1021/bi015982e  PMID:12022872
  • Lisman, T., Mosnier, L. O., Lambert, T., Mauser-Bunschoten, E. P., Meijers, J. C. M., Nieuwenhuis, H. K., de Groot, P. G. Inhibition of fibrinolysis by recombinant factor viia in plasma from patients with severe hemophilia a Blood  2002 99:175-179  DOI:10.1182/blood.V99.1.175  PMID:11756168
  • Mosnier, L. O., Elisen, Mglm, Bouma, B. N., Meijers, J. C. M. Protein c inhibitor regulates the thrombin-thrombomodulin complex in the up- and down regulation of tafi activation Thrombosis and Haemostasis  2001 86:1057-1064  PMID:11686324
  • Mosnier, L. O., Lisman, T., van den Berg, H. M., Nieuwenhuis, H. K., Meijers, J. C. M., Bouma, B. N. The defective down regulation of fibrinolysis in haemophilia a can be restored by increasing the tafi plasma concentration Thrombosis and Haemostasis  2001 86:1035-1039  PMID:11686321
  • Mosnier, L. O., Meijers, J. C. M., Bouma, B. N. The role of protein s in the activation of thrombin activatable fibrinolysis inhibitor (tafi) and regulation of fibrinolysis Thrombosis and Haemostasis  2001 86:1040-1046  PMID:11686322
  • Lisman, T., Leebeek, F. W. G., Mosnier, L. O., Bouma, B. N., Meijers, J. C. M., Janssen, H. L. A., Nieuwenhuis, H. K., De Groot, P. G. Thrombin-activatable fibrinolysis inhibitor deficiency in cirrhosis is not associated with increased plasma fibrinolysis Gastroenterology  2001 121:131-139  DOI:10.1053/gast.2001.25481  PMID:11438502
  • Bouma, B. N., Marx, P. F., Mosnier, L. O., Meijers, J. C. M. Thrombin-activatable fibrinolysis inhibitor (tafi, plasma procarboxypeptidase b, procarboxypeptidase r, procarboxypeptidase u) Thrombosis Research  2001 101:329-354  DOI:10.1016/s0049-3848(00)00411-4  PMID:11297751
  • Mosnier, L. O., Meijers, J. C. M., Bouma, B. N. Regulation of fibrinolysis in plasma by tafi and protein c is dependent on the concentration of thrombomodulin Thrombosis and Haemostasis  2001 85:5-11  PMID:11204587
  • Marx, P. F., Hackeng, T. M., Dawson, P. E., Griffin, J. H., Meijers, J. C. M., Bouma, B. N. Inactivation of active thrombin-activable fibrinolysis inhibitor takes place by a process that involves conformational instability rather than proteolytic cleavage Journal of Biological Chemistry  2000 275:12410-12415  DOI:10.1074/jbc.275.17.12410  PMID:10777524
  • Meijers, J. C. M., Oudijk, E. J. D., Mosnier, L. O., Bos, R., Bouma, B. N., Nieuwenhuis, H. K., Fijnheer, R. Reduced activity of tafi (thrombin-activatable fibrinolysis inhibitor) in acute promyelocytic leukaemia British Journal of Haematology  2000 108:518-523  DOI:10.1046/j.1365-2141.2000.01890.x  PMID:10759708
  • Bouma, B. N., Mosnier, L. O., Meijers, J. C. M., Griffin, J. H. Factor XI dependent and independent activation of thrombin activatable fibrinolysis inhibitor (TAFI) in plasma associated with clot formation Thrombosis and Haemostasis  1999 82:1703-1708  PMID:10613658
  • Mosnier, L. O., von dem Borne, P. A. K., Meijers, J. C. M., Bouma, B. N. Plasma tafi levels influence the clot lysis time in healthy individuals in the presence of an intact intrinsic pathway of coagulation Thrombosis and Haemostasis  1998 80:829-835  PMID:9843179
  • Minnema, M. C., Friederich, P. W., Levi, M., von dem Borne, P. A. K., Mosnier, L. O., Meijers, J. C. M., Biemond, B. J., Hack, C. E., Bouma, B. N., ten Cate, H. Enhancement of rabbit jugular vein thrombolysis by neutralization of factor xi - in vivo evidence for a role of factor xi as an anti-fibrinolytic factor Journal of Clinical Investigation  1998 101:10-14  DOI:10.1172/jci781  PMID:9421460
  • vondemBorne, P. A. K., Mosnier, L. O., Tans, G., Meijers, J. C. M., Bouma, B. N. Factor xi activation by meizothrombin: Stimulation by phospholipid vesicles containing both phosphatidylserine and phosphatidylethanolamine Thrombosis and Haemostasis  1997 78:834-839  PMID:9268180