recent publications

• academic article

  • Manna, J. D., Wepy, J. A., Hsu, K. L., Chang, J. W., Cravatt, B. F., Marnett, L. J. Identification of the major prostaglandin glycerol ester hydrolase in human cancer cells Journal of Biological Chemistry  2014 289:33741-33753  DOI:10.1074/jbc.M114.582353  PMID:25301951  PMCID:PMC4256310
  • Sun, X. F., Wang, H. B., Okabe, M., Mackie, K., Kingsley, P. J., Marnett, L. J., Cravatt, B. F., Dey, S. K. Genetic loss of FAAH compromises male fertility in mice Biology of Reproduction  2009 80:235-242  DOI:10.1095/biolreprod.108.072736  PMID:18987328  PMCID:PMC2804815
  • Turman, M. V., Kingsley, P. J., Rouzer, C. A., Cravatt, B. F., Marnett, L. J. Oxidative metabolism of a fatty acid amide hydrolase-regulated lipid, arachidonoyltaurine Biochemistry  2008 47:3917-3925  DOI:10.1021/bi702530z  PMID:18311922  PMCID:PMC2760074
  • Vila, A., Rosengarth, A., Piomelli, D., Cravatt, B., Marnett, L. J. Hydrolysis of prostaglandin glycerol esters by the endocannabinoid-hydrolyzing enzymes, monoacylglycerol lipase and fatty acid amide hydrolase Biochemistry  2007 46:9578-9585  DOI:10.1021/bi7005898  PMID:17649977
  • Wang, H. B., Xie, H. R., Sun, X. F., Kingsley, P. J., Marnett, L. J., Cravatt, B. F., Dey, S. K. Differential regulation of endocannabinoid synthesis and degradation in the uterus during embryo implantation Prostaglandins & Other Lipid Mediators  2007 83:62-74  DOI:10.1016/j.prostaglandins.2006.09.009  PMID:17259073  PMCID:PMC1805469
  • Wang, H., Xie, H., Guo, Y., Zhang, H., Takahashi, T., Kingsley, P. J., Marnett, L. J., Das, S. K., Cravatt, B. F., Dey, S. K. Fatty acid amide hydrolase deficiency limits early pregnancy events Journal of Clinical Investigation  2006 116:2122-2131  DOI:10.1172/jci28621  PMID:16886060  PMCID:PMC1523389
  • Niedernhofer, L. J., Daniels, J. S., Rouzer, C. A., Greene, R. E., Marnett, L. J. Malondialdehyde, a product of lipid peroxidation, is mutagenic in human cells Journal of Biological Chemistry  2003 278:31426-31433  DOI:10.1074/jbc.M212549200  PMID:12775726
  • Niedernhofer, L. J., Riley, M., SchnetzBoutaud, N., Sanduwaran, G., Chaudhary, A. K., Reddy, G. R., Marnett, L. J. Temperature-dependent formation of a conjugate between tris(hydroxymethyl)aminomethane buffer and the malondialdehyde-DNA adduct pyrimidopurinone Chemical Research in Toxicology  1997 10:556-561  DOI:10.1021/tx960191c  PMID:9168253