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Early commitment: T cell progenitors in the blood

Academic Article
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Overview

authors

  • Petrie, Howard

publication date

  • January 2007

journal

  • Immunity  Journal

abstract

  • Thymic lymphopoiesis depends on blood-borne, marrow-derived progenitors, but characterization of these cells, and their lineage potentials, has been difficult. In this issue, Krueger and von Boehmer show some blood cells that are already T lineage restricted, suggesting that T lineage commitment can occur pre-thymically.

subject areas

  • Animals
  • Cell Lineage
  • Hematopoietic Stem Cells
  • Humans
  • Lymphopoiesis
  • T-Lymphocytes
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Identity

International Standard Serial Number (ISSN)

  • 1074-7613

Digital Object Identifier (DOI)

  • 10.1016/j.immuni.2007.01.003

PubMed ID

  • 17241955
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Additional Document Info

start page

  • 7

end page

  • 8

volume

  • 26

issue

  • 1

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