Early commitment: T cell progenitors in the blood

Academic Article

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Overview

authors

• Petrie, Howard

publication date

• January 2007

journal

• Immunity  Journal

abstract

• Thymic lymphopoiesis depends on blood-borne, marrow-derived progenitors, but characterization of these cells, and their lineage potentials, has been difficult. In this issue, Krueger and von Boehmer show some blood cells that are already T lineage restricted, suggesting that T lineage commitment can occur pre-thymically.

subject areas

• Animals
• Cell Lineage
• Hematopoietic Stem Cells
• Humans
• Lymphopoiesis
• T-Lymphocytes

Identity

International Standard Serial Number (ISSN)

• 1074-7613

Digital Object Identifier (DOI)

• 10.1016/j.immuni.2007.01.003

PubMed ID

• 17241955

Additional Document Info

start page

• 7

end page

• 8

volume

• 26

issue

• 1