Evolving protein stability through genetic selection

Academic Article

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Overview

authors

• Wiseman, R. Luke
• Kelly, Jeffery

publication date

• December 2009

journal

• Molecular Cell  Journal

abstract

• In this issue of Molecular Cell, Foit et al. (2009) probe cellular protein folding using a split beta-lactamase approach for evolving protein stability in the absence of any requirement for function.

subject areas

• Carrier Proteins
• Drug Resistance, Bacterial
• Escherichia coli
• Escherichia coli Proteins
• Evolution, Molecular
• Protein Folding
• Protein Stability
• Selection, Genetic

Identity

International Standard Serial Number (ISSN)

• 1097-2765

Digital Object Identifier (DOI)

• 10.1016/j.molcel.2009.11.023

PubMed ID

• 20005835

Additional Document Info

start page

• 730

end page

• 731

volume

• 36

issue

• 5