Chaperoning ribosome assembly

Academic Article

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Overview

authors

• Karbstein, Katrin

publication date

• 2010

journal

• Journal of Cell Biology  Journal

abstract

• Chaperones help proteins fold in all cellular compartments, and many associate directly with ribosomes, capturing nascent chains to assist their folding and prevent aggregation. In this issue, new data from Koplin et al. (2010. J. Cell Biol. doi: 10.1083/jcb.200910074) and Albanèse et al. (2010. J. Cell Biol. doi: 10.1083/jcb.201001054) suggest that in addition to promoting protein folding, the chaperones ribosome-associated complex (RAC), nascent chain-associated complex (NAC), and Jjj1 also help in the assembly of ribosomes.

subject areas

• Models, Biological
• Molecular Chaperones
• Protein Folding
• Ribosomes
• Saccharomyces cerevisiae Proteins

Identity

PubMed Central ID

• PMC2854375

International Standard Serial Number (ISSN)

• 0021-9525

Digital Object Identifier (DOI)

• 10.1083/jcb.201002102

PubMed ID

• 20368615

Additional Document Info

start page

• 11

end page

• 12

volume

• 189

issue

• 1