Pheromone signaling pathways in yeast

Academic Article
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publication date

  • October 1991

abstract

  • The discovery that the transducing G protein of the Saccharomyces cerevisiae mating pheromone response figures centrally in signal adaptation was the focus of considerable excitement in the past year. Not only does activated G alpha in this system stimulate an adaptive signal but G beta undergoes a desensitizing phosphorylation in response to pheromone signaling.