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Pd-catalyzed enantioselective C-H iodination: asymmetric synthesis of chiral diarylmethylamines

Academic Article
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Overview

related to degree

  • Chu, Ling, Ph.D. in Chemistry, Scripps Research 2012 - 2017

authors

  • Wang, X. C.
  • Moore, C. E.
  • Rheingold, A. L.
  • Yu, Jin-Quan
  • Chu, Ling

publication date

  • 2013

journal

  • Journal of the American Chemical Society  Journal

abstract

  • An enantioselective C-H iodination reaction using a mono-N-benzoyl-protected amino acid has been developed for the synthesis of chiral diarylmethylamines. The reaction uses iodine as the sole oxidant and proceeds at ambient temperature and under air.

subject areas

  • Catalysis
  • Crystallography, X-Ray
  • Methylamines
  • Models, Molecular
  • Molecular Structure
  • Organometallic Compounds
  • Palladium
  • Stereoisomerism
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Identity

International Standard Serial Number (ISSN)

  • 0002-7863

Digital Object Identifier (DOI)

  • 10.1021/ja408864c

PubMed ID

  • 24151991
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Additional Document Info

start page

  • 16344

end page

  • 16347

volume

  • 135

issue

  • 44

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