Pd-catalyzed enantioselective C-H iodination: asymmetric synthesis of chiral diarylmethylamines

Academic Article
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publication date

  • 2013

abstract

  • An enantioselective C-H iodination reaction using a mono-N-benzoyl-protected amino acid has been developed for the synthesis of chiral diarylmethylamines. The reaction uses iodine as the sole oxidant and proceeds at ambient temperature and under air.