recent publications
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academic article
- Zhou, T., Lynch, R. M., Chen, L., Acharya, P., Wu, X., Doria-Rose, N. A., Joyce, M. G., Lingwood, D., Soto, C., Bailer, R. T., Ernandes, M. J., Kong, R., et al. Structural repertoire of HIV-1-neutralizing antibodies targeting the CD4 supersite in 14 donors Cell 2015 161:1280-1292 DOI:10.1016/j.cell.2015.05.007 PMID:26004070 PMCID:PMC4683157
- Deng, X., Liang, H., Ulanovskaya, O. A., Ji, Q., Zhou, T., Sun, F., Lu, Z., Hutchison, A. L., Lan, L., Wu, M., Cravatt, B. F., He, C. Steady-state hydrogen peroxide induces glycolysis in Staphylococcus aureus and Pseudomonas aeruginosa Journal of Bacteriology 2014 196:2499-2513 DOI:10.1128/jb.01538-14 PMID:24769698 PMCID:PMC4097596
- Zhou, T., Zhu, J., Yang, Y., Gorman, J., Ofek, G., Srivatsan, S., Druz, A., Lees, C. R., Lu, G., Soto, C., Stuckey, J., Burton, D. R., et al. Transplanting supersites of HIV-1 vulnerability PLoS One 2014 9:e99881 DOI:10.1371/journal.pone.0099881 PMID:24992528 PMCID:PMC4084637
- Liao, H. X., Lynch, R., Zhou, T., Gao, F., Alam, S. M., Boyd, S. D., Fire, A. Z., Roskin, K. M., Schramm, C. A., Zhang, Z., Zhu, J., Shapiro, L., et al. Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus Nature 2013 496:469-476 DOI:10.1038/nature12053 PMID:23552890 PMCID:PMC3637846
- Zhu, J., Wu, X., Zhang, B., McKee, K., O'Dell, S., Soto, C., Zhou, T., Casazza, J. P., NISC Comparative Sequencing Program, Mullikin, J. C., Kwong, P. D., Mascola, J. R., et al. De novo identification of VRC01 class HIV-1-neutralizing antibodies by next-generation sequencing of B-cell transcripts Proceedings of the National Academy of Sciences of the United States of America 2013 110:E4088-E4097 DOI:10.1073/pnas.1306262110 PMID:24106303 PMCID:PMC3808619
- Zhou, T., Zhu, J., Wu, X., Moquin, S., Zhang, B., Acharya, P., Georgiev, I. S., Altae-Tran, H. R., Chuang, G. Y., Joyce, M. G., Kwon, Y. D., Longo, N. S., et al. Multidonor analysis reveals structural elements, genetic determinants, and maturation pathway for HIV-1 neutralization by VRC01-class antibodies Immunity 2013 39:245-258 DOI:10.1016/j.immuni.2013.04.012 PMID:23911655 PMCID:PMC3985390
- Joyce, M. G., Kanekiyo, M., Xu, L., Biertumpfel, C., Boyington, J. C., Moquin, S., Shi, W., Wu, X., Yang, Y., Yang, Z. Y., Zhang, B., Zheng, A., et al. Outer domain of HIV-1 gp120: antigenic optimization, structural malleability, and crystal structure with antibody VRC-PG04 Journal of Virology 2013 87:2294-2306 DOI:10.1128/jvi.02717-12 PMID:23236069 PMCID:PMC3571475
- Li, K., Zhou, T., Liao, L., Yang, Z., Wong, C., Henn, F., Malinow, R., Yates, J. R., Hu, H. L. betaCaMKII in lateral habenula mediates core symptoms of depression Science 2013 341:1016-1020 DOI:10.1126/science.1240729 PMID:23990563 PMCID:PMC3932364
- Kwon, Y. D., Finzi, A., Wu, X., Dogo-Isonagie, C., Lee, L. K., Moore, L. R., Schmidt, S. D., Stuckey, J., Yang, Y., Zhou, T., Zhu, J., Vicic, D. A., et al. Unliganded HIV-1 gp120 core structures assume the CD4-bound conformation with regulation by quaternary interactions and variable loops Proceedings of the National Academy of Sciences of the United States of America 2012 109:5663-5668 DOI:10.1073/pnas.1112391109 PMID:22451932 PMCID:PMC3326499
- Pancera, M., McLellan, J. S., Wu, X., Zhu, J., Changela, A., Schmidt, S. D., Yang, Y., Zhou, T., Phogat, S., Mascola, J. R., Kwong, P. D. Crystal structure of PG16 and chimeric dissection with somatically related PG9: structure-function analysis of two quaternary-specific antibodies that effectively neutralize HIV-1 Journal of Virology 2010 84:8098-8110 DOI:10.1128/jvi.00966-10 PMID:20538861 PMCID:PMC2916520
- Zhou, T., Georgiev, I., Wu, X., Yang, Z. Y., Dai, K., Finzi, A., Kwon, Y. D., Scheid, J. F., Shi, W., Xu, L., Yang, Y., Zhu, J., et al. Structural basis for broad and potent neutralization of HIV-1 by antibody VRC01 Science 2010 329:811-817 DOI:10.1126/science.1192819 PMID:20616231 PMCID:PMC2981354