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Mouse liver-specific CD8(+) T-cells encounter their cognate antigen and acquire capacity to destroy target hepatocytes

Academic Article
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  • Research
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Overview

authors

  • Chabot, S.
  • Fakhfakh, A.
  • Beland, K.
  • Lamarre, A.
  • Oldstone, Michael
  • Alvarez, F.
  • Djilali-Saiah, I.

publication date

  • May 2013

journal

  • Journal of Autoimmunity  Journal

subject areas

  • Animals
  • Antigens, Viral
  • Apoptosis
  • CD8-Positive T-Lymphocytes
  • Cells, Cultured
  • Cytotoxicity, Immunologic
  • Disease Models, Animal
  • Female
  • Hepatitis, Autoimmune
  • Hepatocytes
  • Liver
  • Lymphocytic choriomeningitis virus
  • Male
  • Mice
  • Mice, Inbred C57BL
  • Mice, Transgenic
  • Nucleoproteins
  • Organ Specificity
  • Transgenes
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Research

keywords

  • Autoimmune hepatitis
  • Autoreactive CD8(+) T-cells
  • Peripheral tolerance mechanisms
  • Transgenic mouse model
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Identity

PubMed Central ID

  • PMC4465814

International Standard Serial Number (ISSN)

  • 0896-8411

Digital Object Identifier (DOI)

  • 10.1016/j.jaut.2012.10.002

PubMed ID

  • 23137675
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Additional Document Info

start page

  • 19

end page

  • 28

volume

  • 42

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