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A naturally occurring brominated furanone covalently modifies and inactivates LuxS

Academic Article
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  • Research
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Overview

authors

  • Zang, T.
  • Lee, B. W.
  • Cannon, L. M.
  • Ritter, K. A.
  • Dai, S.
  • Ren, D.
  • Wood, T. K.
  • Zhou, Zhaohui Sunny

publication date

  • November 2009

journal

  • Bioorganic & Medicinal Chemistry Letters  Journal

subject areas

  • Anti-Bacterial Agents
  • Bacterial Proteins
  • Bromine
  • Carbon-Sulfur Lyases
  • Enzyme Inhibitors
  • Furans
  • Rhodophyta
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Research

keywords

  • AI-2
  • Autoinducer
  • Biofilm
  • Brominated furanone
  • Covalent modification
  • Enzyme inhibition
  • Halogenated furanone
  • LuxS
  • Natural products
  • Quorum sensing
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Identity

PubMed Central ID

  • PMC2760616

International Standard Serial Number (ISSN)

  • 0960-894X

Digital Object Identifier (DOI)

  • 10.1016/j.bmcl.2009.08.095

PubMed ID

  • 19775890
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Additional Document Info

start page

  • 6200

end page

  • 6204

volume

  • 19

issue

  • 21

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