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Inhibition of inflammation with celastrol fails to improve muscle function in dysferlin-deficient A/J mice

Academic Article
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  • Research
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Overview

authors

  • Dillingham, Blythe C.
  • Klimek, M. E. B.
  • Gernapudi, R.
  • Rayavarapu, S.
  • Gallardo, E.
  • Van der Meulen, J. H.
  • Jordan, S.
  • Ampong, B.
  • Gordish-Dressman, H.
  • Spurney, C. F.
  • Nagaraju, K.

publication date

  • September 2015

journal

  • Journal of the Neurological Sciences  Journal

subject areas

  • Analysis of Variance
  • Animals
  • Body Weight
  • Cytokines
  • Disease Models, Animal
  • Dysferlin
  • Echocardiography
  • Female
  • Gene Expression Regulation
  • In Vitro Techniques
  • Inflammation
  • Male
  • Membrane Proteins
  • Mice
  • Mice, Inbred C57BL
  • Mice, Mutant Strains
  • Muscle Strength
  • Muscle, Skeletal
  • Muscular Dystrophies, Limb-Girdle
  • Triterpenes
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Research

keywords

  • Celastrol
  • Dysferlin
  • Inflammation
  • Muscular dystrophy
  • NF-kappa B
  • Skeletal muscle
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Identity

PubMed Central ID

  • PMC4545396

International Standard Serial Number (ISSN)

  • 0022-510X

Digital Object Identifier (DOI)

  • 10.1016/j.jns.2015.06.042

PubMed ID

  • 26119397
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Additional Document Info

start page

  • 157

end page

  • 162

volume

  • 356

issue

  • 1-2

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