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Selective inhibition of oncogenic KRAS output with small molecules targeting the inactive state

Academic Article
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  • Overview
  • Identity
  • Additional Document Info
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Overview

authors

  • Patricelli, Matt
  • Janes, M. R.
  • Li, L. S.
  • Hansen, R.
  • Peters, U.
  • Kessler, L. V.
  • Chen, Y.
  • Kucharski, J. M.
  • Feng, J.
  • Ely, T.
  • Chen, J. H.
  • Firdaus, S. J.
  • Babbar, A.
  • Ren, P. D.
  • Liu, Y.

publication date

  • March 2016

journal

  • Cancer Discovery  Journal

subject areas

  • Antineoplastic Agents
  • Biomarkers
  • Cell Line, Tumor
  • Cell Transformation, Neoplastic
  • Dose-Response Relationship, Drug
  • Drug Screening Assays, Antitumor
  • Humans
  • Ligands
  • Models, Biological
  • Models, Molecular
  • Molecular Conformation
  • Protein Kinase Inhibitors
  • Recombinant Proteins
  • Signal Transduction
  • Structure-Activity Relationship
  • ras Proteins
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Identity

International Standard Serial Number (ISSN)

  • 2159-8274

Digital Object Identifier (DOI)

  • 10.1158/2159-8290.cd-15-1105

PubMed ID

  • 26739882
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Additional Document Info

start page

  • 316

end page

  • 329

volume

  • 6

issue

  • 3

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