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Potential beneficial metabolic interactions between tamoxifen and Isoflavones via cytochrome P450-mediated pathways in female rat liver microsomes

Academic Article
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Overview

authors

  • Chen, J.
  • Halls, S. C.
  • Alfaro, J. F.
  • Zhou, Zhaohui Sunny
  • Hu, M.

publication date

  • November 2004

journal

  • Pharmaceutical Research  Journal

subject areas

  • Algorithms
  • Animals
  • Antineoplastic Agents
  • Chromatography, High Pressure Liquid
  • Cytochrome P-450 Enzyme Inhibitors
  • Cytochrome P-450 Enzyme System
  • Drug Interactions
  • Enzyme Inhibitors
  • Female
  • Genistein
  • In Vitro Techniques
  • Isoflavones
  • Microsomes, Liver
  • Rats
  • Rats, Sprague-Dawley
  • Tamoxifen
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Research

keywords

  • cytochrome P450
  • drug interaction
  • genistein
  • rat liver microsomes
  • tamoxifen
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Identity

International Standard Serial Number (ISSN)

  • 0724-8741

Digital Object Identifier (DOI)

  • 10.1023/B:PHAM.0000048202.92930.61

PubMed ID

  • 15587933
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Additional Document Info

start page

  • 2095

end page

  • 2104

volume

  • 21

issue

  • 11

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