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The C9orf72-interacting protein Smcr8 is a negative regulator of autoimmunity and lysosomal exocytosis

Academic Article
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  • Research
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Overview

authors

  • Zhang, Y.
  • Burberry, A.
  • Wang, J. Y.
  • Sandoe, J.
  • Ghosh, Sulagna
  • Udeshi, N. D.
  • Svinkina, T.
  • Mordes, D. A.
  • Mok, J.
  • Charlton, M.
  • Li, Q. Z.
  • Carr, S. A.
  • Eggan, K.

publication date

  • July 2018

journal

  • Genes & Development  Journal

subject areas

  • Amyotrophic Lateral Sclerosis
  • Animals
  • Autoimmunity
  • C9orf72 Protein
  • Carrier Proteins
  • Exocytosis
  • Gene Expression Regulation
  • Humans
  • Lymph Nodes
  • Lysosomal-Associated Membrane Protein 1
  • Lysosomes
  • Macrophages
  • Mice
  • Mice, Knockout
  • Mutation
  • Protein Isoforms
  • Protein Stability
  • Splenomegaly
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Research

keywords

  • C9ORF72
  • SMCR8
  • amyotrophic lateral sclerosis (ALS)
  • autoimmunity
  • autophagy
  • lysosome
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Identity

PubMed Central ID

  • PMC6075033

International Standard Serial Number (ISSN)

  • 0890-9369

Digital Object Identifier (DOI)

  • 10.1101/gad.313932.118

PubMed ID

  • 29950492
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Additional Document Info

start page

  • 929

end page

  • 943

volume

  • 32

issue

  • 13-14

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