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N-methyl, N-propynyl-2-phenylethylamine (MPPE), a selegiline analog, attenuates MPTP-induced dopaminergic toxicity with guaranteed behavioral safety: involvement of inhibitions of mitochondrial oxidative burdens and p53 gene-elicited pro-apoptotic change

Academic Article
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Overview

authors

  • Shin, E. J.
  • Nam, Y.
  • Lee, J. W.
  • Nguyen, P. K. T.
  • Yoo, J. E.
  • Tran, T. V.
  • Jeong, J. H.
  • Jang, Choon-Gon
  • Oh, Y. J.
  • Youdim, M. B. H.
  • Lee, P. H.
  • Nabeshima, T.
  • Kim, H. C.

publication date

  • November 2016

journal

  • Molecular Neurobiology  Journal
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Research

keywords

  • Behavioral safety
  • Mitochondria
  • N-Methyl, N-propynyl-2-phenylethylamine
  • Oxidative stress
  • Parkinson's disease
  • Pro-apoptosis
  • Selegiline
  • p53 gene knockoutmice
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Identity

International Standard Serial Number (ISSN)

  • 0893-7648

Digital Object Identifier (DOI)

  • 10.1007/s12035-015-9527-1

PubMed ID

  • 26563498
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Additional Document Info

start page

  • 6251

end page

  • 6269

volume

  • 53

issue

  • 9

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