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Disruption of TET2 promotes the therapeutic efficacy of CD19-targeted T cells

Academic Article
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  • Additional Document Info
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Overview

authors

  • Fraietta, J. A.
  • Nobles, C. L.
  • Sammons, M. A.
  • Lundh, S.
  • Carty, S. A.
  • Reich, T. J.
  • Cogdill, A. P.
  • Morrissette, J. J. D.
  • DeNizio, J. E.
  • Reddy, S.
  • Hwang, Y.
  • Gohil, M.
  • Kulikovskaya, I.
  • Nazimuddin, F.
  • Gupta, M.
  • Chen, F.
  • Everett, J. K.
  • Alexander, K. A.
  • Lin-Shiao, E.
  • Gee, M. H.
  • Liu, X.
  • Young, R. M.
  • Ambrose, D.
  • Wang, Y.
  • Xu, J.
  • Jordan, M. S.
  • Marcucci, Katherine
  • Levine, B. L.
  • Garcia, K. C.
  • Zhao, Y.
  • Kalos, M.
  • Porter, D. L.
  • Kohli, R. M.
  • Lacey, S. F.
  • Berger, S. L.
  • Bushman, F. D.
  • June, C. H.
  • Melenhorst, J. J.

publication date

  • June 2018

journal

  • Nature  Journal

subject areas

  • 5-Methylcytosine
  • Adoptive Transfer
  • Aged
  • Alleles
  • Antigens, CD19
  • Cell Differentiation
  • Clinical Trials as Topic
  • Clone Cells
  • Dioxygenases
  • Epigenesis, Genetic
  • HEK293 Cells
  • Humans
  • Immunotherapy
  • Leukemia, Lymphocytic, Chronic, B-Cell
  • Male
  • Mutation
  • Recombinant Fusion Proteins
  • T-Lymphocytes
  • Transgenes
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Identity

PubMed Central ID

  • PMC6320248

International Standard Serial Number (ISSN)

  • 0028-0836

Digital Object Identifier (DOI)

  • 10.1038/s41586-018-0178-z

PubMed ID

  • 29849141
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Additional Document Info

start page

  • 307

end page

  • 312

volume

  • 558

issue

  • 7709

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