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Linking high-throughput screens to identify MoAs and novel inhibitors of Mycobacterium tuberculosis dihydrofolate reductase

Academic Article
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Overview

authors

  • Maria, J. P. S.
  • Park, Y.
  • Yang, L.
  • Murgolo, N.
  • Altman, M. D.
  • Zuck, P.
  • Adam, Gregory
  • Chamberlin, C.
  • Saradjian, P.
  • Dandliker, P.
  • Boshoff, H. I. M.
  • Barry, C. E.
  • Garlisi, C.
  • Olsen, D. B.
  • Young, K.
  • Glick, M.
  • Nickbarg, E.
  • Kutchukian, P. S.

publication date

  • September 2017

journal

  • ACS Chemical Biology  Journal

subject areas

  • Antitubercular Agents
  • Drug Evaluation, Preclinical
  • Folic Acid Antagonists
  • HeLa Cells
  • High-Throughput Screening Assays
  • Humans
  • Ligands
  • Molecular Docking Simulation
  • Mycobacterium tuberculosis
  • Tetrahydrofolate Dehydrogenase
  • Tuberculosis
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Identity

International Standard Serial Number (ISSN)

  • 1554-8929

Digital Object Identifier (DOI)

  • 10.1021/acschembio.7b00468

PubMed ID

  • 28806050
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Additional Document Info

start page

  • 2448

end page

  • 2456

volume

  • 12

issue

  • 9

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