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A survey of ancient conserved non-coding elements in the PAX6 locus reveals a landscape of interdigitated cis-regulatory archipelagos

Academic Article
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Overview

authors

  • Bhatia, S.
  • Monahan, J.
  • Ravi, V.
  • Gautier, P.
  • Murdoch, E.
  • Brenner, Sydney
  • van Heyningen, V.
  • Venkatesh, B.
  • Kleinjan, D. A.

publication date

  • March 2014

journal

  • Developmental Biology  Journal

subject areas

  • Animals
  • Animals, Genetically Modified
  • Base Sequence
  • Cell Line
  • Chickens
  • Conserved Sequence
  • Enhancer Elements, Genetic
  • Eye
  • Eye Proteins
  • Gene Expression Regulation, Developmental
  • Genes, Developmental
  • Gnathostoma
  • Homeodomain Proteins
  • Humans
  • Mice
  • Opossums
  • Paired Box Transcription Factors
  • Promoter Regions, Genetic
  • RNA, Untranslated
  • Regulatory Sequences, Nucleic Acid
  • Repressor Proteins
  • Sequence Analysis, DNA
  • Sharks
  • Xenopus
  • Zebrafish
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Research

keywords

  • Ancient conserved gnathostome enhancers
  • Elephant shark
  • Long-range enhancers
  • PAX6
  • Regulatory archipelagos
  • Reporter transgenics
  • cis-Regulatory landscape
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Identity

International Standard Serial Number (ISSN)

  • 0012-1606

Digital Object Identifier (DOI)

  • 10.1016/j.ydbio.2014.01.007

PubMed ID

  • 24440152
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Additional Document Info

start page

  • 214

end page

  • 228

volume

  • 387

issue

  • 2

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