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The proliferative potential of hematopoietic stem cells (CFUs) during serial passage in irradiated mice as foci of ectopic hematopoiesis [Article in Russian]

Academic Article
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Overview

authors

  • Deryugina, Elena
  • Drize, N. I.
  • Udalov, G. A.
  • Chertkov, I. L.

publication date

  • December 1988

journal

  • Bulletin of Experimental Biology and Medicine  Journal

abstract

  • During serial passages of hemopoietic tissue as a whole ectopic hemopoietic site under renal capsule of irradiated mice gradual decrease of proliferative potential of CFUs has been observed. The results suggest that the most probable cause of such decline is random loss of precursor cells with high but limited proliferative potential during serial passages of hemopoietic tissue.

subject areas

  • Animals
  • Bone Marrow
  • Bone Marrow Cells
  • Bone Marrow Transplantation
  • Cell Division
  • Colony-Forming Units Assay
  • Female
  • Hematopoiesis, Extramedullary
  • Hematopoietic Stem Cell Transplantation
  • Hematopoietic Stem Cells
  • Kidney
  • Male
  • Mice
  • Mice, Inbred C57BL
  • Mice, Inbred CBA
  • Transplantation, Isogeneic
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Identity

International Standard Serial Number (ISSN)

  • 0007-4888

Digital Object Identifier (DOI)

  • 10.1007/bf00802189

PubMed ID

  • 2905178
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Additional Document Info

start page

  • 1758

end page

  • 1760

volume

  • 106

issue

  • 12

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