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Mechanism of Action of an Imidopiperidine Inhibitor of Human Polynucleotide Kinase/Phosphatase

Academic Article
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  • Additional Document Info
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Overview

authors

  • Freschauf, G. K.
  • Mani, R. S.
  • Mereniuk, T. R.
  • Fanta, M.
  • Virgen, Cesar Antonio
  • Dianov, G. L.
  • Grassot, J. M.
  • Hall, D. G.
  • Weinfeld, M.

publication date

  • January 2010

journal

  • Journal of Biological Chemistry  Journal

subject areas

  • Adenosine Triphosphate
  • Antineoplastic Agents, Phytogenic
  • Binding Sites
  • Camptothecin
  • Cell Survival
  • Circular Dichroism
  • DNA Ligase ATP
  • DNA Ligases
  • DNA Polymerase beta
  • DNA Repair
  • DNA Repair Enzymes
  • Drug Resistance, Neoplasm
  • Enzyme Inhibitors
  • Etoposide
  • Fluorescence Resonance Energy Transfer
  • Humans
  • Lung Neoplasms
  • Mutagenesis, Site-Directed
  • Phosphotransferases (Alcohol Group Acceptor)
  • Photoelectron Spectroscopy
  • Piperidines
  • Poly-ADP-Ribose Binding Proteins
  • Protein Conformation
  • Pyrroles
  • Radiation-Sensitizing Agents
  • Tumor Cells, Cultured
  • Xenopus Proteins
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Identity

PubMed Central ID

  • PMC2807293

International Standard Serial Number (ISSN)

  • 0021-9258

Digital Object Identifier (DOI)

  • 10.1074/jbc.M109.055764

PubMed ID

  • 19940137
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Additional Document Info

start page

  • 2351

end page

  • 2360

volume

  • 285

issue

  • 4

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